PANTHER Gene Information

Gene Symbol(s):

tig-3

Organism:

Caenorhabditis elegans

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Gene Name:

TGF-beta family profile domain-containing protein

Gene ID:

CELE_Y46E12BL.1

Protein ID:

A0A8S4QGI4

Persistent Id:

PTN008983486

Alternate Ids:

BX284602(EMBL)	A0A8S4QGI4(Synonym)
A0A8S4QGI4_CAEEL(UniProtKB-ID)	CAH2172265(EMBL-CDS)
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PANTHER Classification

PANTHER Family:	TGF-BETA FAMILY (PTHR11848)
PANTHER Subfamily:	INHIBIN BETA CHAIN (PTHR11848:SF309)
PANTHER GO-slim Molecular Function:	cytokine activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	growth factor

Pathway Categories:

Activin beta signaling pathway

activin beta

BMP/activin signaling pathway-drosophila

BMP/activin orthologous ligands

TGF-beta signaling pathway

Transforming growth factor beta

BMP/activin signaling pathway-drosophila

BMP/activin orthologous ligands

Activin beta signaling pathway

activin beta

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	growth factor activity, cytokine activity
GO BP Complete:	signal transduction
GO CC Complete:	extracellular space, extracellular region

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6067\|UniProtKB=P09529	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000046739.1\|UniProtKB=A0A2I3TNV9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000015308.3\|UniProtKB=G3RH13	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000060196.1\|UniProtKB=A0A5F8ALK5	Macaca mulatta	O
MOUSE\|MGI=MGI=96571\|UniProtKB=Q04999	Mus musculus	O
RAT\|RGD=2913\|UniProtKB=P17491	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000049058.1\|UniProtKB=A0A3Q1LMU4	Bos taurus	O
BOVIN\|Gene=INHBB\|UniProtKB=P42917	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000038610.2\|UniProtKB=A0A287BPF5	Sus scrofa	O
PIG\|Gene=INHBB\|UniProtKB=P04088	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000014285.3\|UniProtKB=F7A1Y1	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000042797.2\|UniProtKB=A0A337RU16	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845027084.1\|UniProtKB=A0A8I3SAJ4	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000042727.1\|UniProtKB=A0A5F8HIU4	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000042798.1\|UniProtKB=A0A6I8NNB7	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010018937.1\|UniProtKB=R4GIS0	Gallus gallus	O
CHICK\|Gene=INHBB\|UniProtKB=P27093	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000004094.4\|UniProtKB=R4GDL9	Anolis carolinensis	O
XENLA\|Gene=inhbb.S\|UniProtKB=A0A1L8ENH9	Xenopus laevis	O
XENLA\|Gene=inhbb.L\|UniProtKB=Q91350	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000044060\|UniProtKB=A0A803JF31	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000001340.2\|UniProtKB=H2L746	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-990415-2\|UniProtKB=B0S7E0	Danio rerio	O
DANRE\|Gene=LOC100332902\|UniProtKB=A0A8M2BK93	Danio rerio	O
DANRE\|Gene=LOC101887111\|UniProtKB=A0A8M2BK69	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000002019.1\|UniProtKB=W5M1T3	lepisosteus oculatus	O
HUMAN\|HGNC=6065\|UniProtKB=P05111	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000012964.3\|UniProtKB=H2QJH4	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000003603.3\|UniProtKB=G3QM12	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000007483.4\|UniProtKB=Q5SEJ5	Macaca mulatta	O
MOUSE\|MGI=MGI=96569\|UniProtKB=Q04997	Mus musculus	O
RAT\|RGD=2912\|UniProtKB=P17490	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000009972\|UniProtKB=P07994	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000020771\|UniProtKB=P04087	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000015864.3\|UniProtKB=F6UTU7	Equus caballus	O
HORSE\|Gene=INHA\|UniProtKB=P55101	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000006667.5\|UniProtKB=M3W6A9	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845030507.1\|UniProtKB=A0A8I3SCQ0	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000047853.1\|UniProtKB=A0A5F8GV02	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000042869.1\|UniProtKB=A0A6I8MXM2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010021163.1\|UniProtKB=A0A8V0ZI36	Gallus gallus	O
CHICK\|Gene=INHA\|UniProtKB=P43031	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000042878.1\|UniProtKB=A0A803T6Y0	Anolis carolinensis	O
XENLA\|Gene=LOC100127301\|UniProtKB=A9JS42	Xenopus laevis	O
XENLA\|Gene=inha.L\|UniProtKB=A9JS55	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-853910\|UniProtKB=Q4V787	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000002184.2\|UniProtKB=H2LA10	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060503-554\|UniProtKB=Q1LYE4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009276.1\|UniProtKB=W5MSF5	lepisosteus oculatus	O
HUMAN\|HGNC=6066\|UniProtKB=P08476	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000044337.1\|UniProtKB=H2QUH0	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000042209.1\|UniProtKB=A0A2I2ZMR9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000061466.1\|UniProtKB=G7MLF8	Macaca mulatta	LDO
MOUSE\|MGI=MGI=96570\|UniProtKB=Q04998	Mus musculus	LDO
RAT\|RGD=62074\|UniProtKB=P18331	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000048508\|UniProtKB=P07995	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000035077\|UniProtKB=P03970	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022448.4\|UniProtKB=A0A3Q2LFL1	Equus caballus	LDO
HORSE\|Gene=INHBA\|UniProtKB=P55102	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000010866\|UniProtKB=Q6X2S4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845018632.1\|UniProtKB=A0A8I3P2Y0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000002721.5\|UniProtKB=H9H613	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000010700.5\|UniProtKB=F6SCP7	Ornithorhynchus anatinus	LDO
CHICK\|Gene=INHBA\|UniProtKB=P27092	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010007868.1\|UniProtKB=A0A8V0XUA9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000017576.4\|UniProtKB=G1KU54	Anolis carolinensis	LDO
XENLA\|Gene=inhba.S\|UniProtKB=A0A1L8FRS5	Xenopus laevis	O
XENLA\|Gene=inhba.L\|UniProtKB=A0A1L8FWM6	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-491002\|UniProtKB=F6XFQ8	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000008081.2\|UniProtKB=H2LVL2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050525-2\|UniProtKB=A1L1T8	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000025793.1\|UniProtKB=A0A3B3HN83	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-000210-21\|UniProtKB=Q8QGE3	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011979.1\|UniProtKB=W5N270	lepisosteus oculatus	LDO
HUMAN\|HGNC=30142\|UniProtKB=Q99988	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000010707.4\|UniProtKB=H2QFT1	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000016924.3\|UniProtKB=G3RL77	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000050122.1\|UniProtKB=A0A5F7ZP77	Macaca mulatta	O
MOUSE\|MGI=MGI=1346047\|UniProtKB=Q9Z0J7	Mus musculus	O
RAT\|RGD=2674\|UniProtKB=Q9Z0J6	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000015618.6\|UniProtKB=E1BBL5	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000034260.2\|UniProtKB=D3Y269	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000039579.2\|UniProtKB=A0A3Q2GZK8	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000009733.4\|UniProtKB=M3WC01	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845022411.1\|UniProtKB=A0A8I3PB42	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000023947.3\|UniProtKB=A0A5F8HDP5	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000001923.2\|UniProtKB=A0A6I8NY58	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010027172.1\|UniProtKB=A0A8V1AF44	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000040409.1\|UniProtKB=A0A803TDR7	Anolis carolinensis	O
XENLA\|Gene=gdf15.L\|UniProtKB=A0A8J0V1Q7	Xenopus laevis	O
XENLA\|Gene=gdf15.S\|UniProtKB=A0A1L8HNP6	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5714902\|UniProtKB=A0A803JR63	Xenopus tropicalis	O
DANRE\|Gene=LOC101886665\|UniProtKB=A0A8M9PIY4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000007803.1\|UniProtKB=W5MM58	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000001470.1\|UniProtKB=W5LZX5	lepisosteus oculatus	O
HUMAN\|HGNC=6068\|UniProtKB=P55103	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000005130.4\|UniProtKB=H2Q6B1	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000022398.2\|UniProtKB=G3S8C9	Gorilla gorilla gorilla	O
MOUSE\|MGI=MGI=105932\|UniProtKB=P55104	Mus musculus	O
RAT\|RGD=621194\|UniProtKB=Q9WUK5	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000019084.5\|UniProtKB=E1B7M7	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000037446.2\|UniProtKB=A0A286ZIJ6	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000010945.4\|UniProtKB=F7DPX5	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000032733.3\|UniProtKB=A0A2I2U528	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845011778.1\|UniProtKB=A0A8I3N9C1	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000006001.4\|UniProtKB=H9H666	Monodelphis domestica	O
CHICK\|Ensembl=ENSGALG00010025533.1\|UniProtKB=A0A8V0ZY31	Gallus gallus	O
HUMAN\|HGNC=24029\|UniProtKB=P58166	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000005132.3\|UniProtKB=H2Q6B2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002772.3\|UniProtKB=G3QJX2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000001124.4\|UniProtKB=F6TA61	Macaca mulatta	O
MOUSE\|MGI=MGI=109269\|UniProtKB=O08717	Mus musculus	O
RAT\|RGD=621196\|UniProtKB=O88959	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000006599.4\|UniProtKB=E1BFT5	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000000442.4\|UniProtKB=F1SKG1	Sus scrofa	O
FELCA\|Ensembl=ENSFCAG00000003217.5\|UniProtKB=M3VZY2	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845011799.1\|UniProtKB=A0A8I3NAL4	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000039683.1\|UniProtKB=A0A6I8NPR8	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000043557.1\|UniProtKB=A0A6I8N4W5	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010025546.1\|UniProtKB=A0A3Q2TUG3	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000035671.1\|UniProtKB=A0A803T6C6	Anolis carolinensis	O
XENLA\|Gene=inhbc.2.L\|UniProtKB=A0A1L8HI52	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-1217521\|UniProtKB=A0A6I8RMP3	Xenopus tropicalis	O
XENLA\|Gene=inhbc.1.S\|UniProtKB=A0A1L8H9U5	Xenopus laevis	O
XENLA\|Gene=inhbc.1.L\|UniProtKB=Q91696	Xenopus laevis	O
ORYLA\|Ensembl=ENSORLG00000005461.2\|UniProtKB=H2LLG3	Oryzias latipes	O
DANRE\|Gene=LOC100329520\|UniProtKB=A0A8M1RDL3	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000005963.1\|UniProtKB=W5MFP1	lepisosteus oculatus	O
BRAFL\|Gene=LOC118423922\|UniProtKB=A0A9J7N3A4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC100147806\|UniProtKB=B2YGG4	Strongylocentrotus purpuratus	LDO
CAEBR\|Gene_ORFName=CBG20656\|UniProtKB=A8XYB0	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00107742\|UniProtKB=A0A2A6C891	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00278464\|UniProtKB=A0A454Y4J7	Pristionchus pacificus	LDO
PRIPA\|EnsemblGenome=WBGene00272968\|UniProtKB=A0A454XJT7	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00273955\|UniProtKB=A0A2A6B6K2	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00096903\|UniProtKB=A0A2A6C8S7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0024913\|UniProtKB=O61643	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP000342\|UniProtKB=A0A1S4G8N6	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC015808\|UniProtKB=D2A422	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_305466\|UniProtKB=E9FWU5	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW008819\|UniProtKB=B7PZ52	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW016200\|UniProtKB=B7P4B4	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG111242\|UniProtKB=T1EF97	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g196852\|UniProtKB=A7RGJ4	Nematostella vectensis	O