PANTHER Gene Information   
Gene Symbol(s): act-1
Organism: Caenorhabditis elegans
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Gene Name: Actin-1
Gene ID: WBGene00000063
Protein ID: P0DM41
Persistent Id: PTN000233442
Alternate Ids:
CE13148(WormBase_PRO) 519881597(GI)
CAA34717(EMBL-CDS) 179535(GeneID)
3.6.4.- {ECO:0000250|UniProtKB:P68137}(EC) WBGene00000063(Ensembl)
ACT1_CAEEL(UniProtKB-ID) NP_505817(refSeq)
T04C12.6(Ensembl_TRS) ACT1(Synonym)
T04C12.6(Ensembl_PRO) act-1(Symbol)
WBGene00000063(WormBase) T04C12(WormBase_TRS)
X16796(EMBL) P10985(AltAccession)
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PANTHER Classification
PANTHER Family: ACTIN (PTHR11937)
PANTHER Subfamily: ACTIN-1-RELATED (PTHR11937:SF471)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process: mitotic cytokinesis
PANTHER GO-slim Cellular Component: actin cytoskeleton
PANTHER protein class: actin and actin related protein
Pathway Categories: Cadherin signaling pathway
   Filamentous F-actin
Alzheimer disease-presenilin pathway
   actin
Inflammation mediated by chemokine and cytokine signaling pathway
   F-actin
Cytoskeletal regulation by Rho GTPase
   Actin
Nicotinic acetylcholine receptor signaling pathway
   Actin
Huntington disease
   Actin

GO MF Complete: nucleotide binding, ATP binding, structural constituent of cytoskeleton, hydrolase activity
GO BP Complete: cortical actin cytoskeleton organization, mitotic cytokinesis, embryo development ending in birth or egg hatching
GO CC Complete: striated muscle thin filament, cytoskeleton, cytoplasm, actin cytoskeleton
Reactome Pathways: MAPK1/MAPK3 signaling, Gap junction degradation, Signal Transduction, Innate Immune System, Signaling by Rho GTPases, Signaling by VEGF, Nervous system development, RHO GTPases Activate WASPs and WAVEs, Developmental Biology, Vesicle-mediated transport, RHOF GTPase cycle, Membrane Trafficking, Response to elevated platelet cytosolic Ca2+, EPH-ephrin mediated repulsion of cells, Fcgamma receptor (FCGR) dependent phagocytosis, Regulation of actin dynamics for phagocytic cup formation, EPHB-mediated forward signaling, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Axon guidance, Signaling by Receptor Tyrosine Kinases, Immune System, MAP2K and MAPK activation, RAF/MAP kinase cascade, L1CAM interactions, Platelet activation, signaling and aggregation, Hemostasis, MAPK family signaling cascades, Recycling pathway of L1, VEGFA-VEGFR2 Pathway, RHO GTPases Activate Formins, Cell junction organization, Cell-Cell communication, EPH-Ephrin signaling, Clathrin-mediated endocytosis, Cell-extracellular matrix interactions, Formation of annular gap junctions, RHO GTPase Effectors, Platelet degranulation , RHO GTPase cycle, RHO GTPases activate IQGAPs, Gap junction trafficking, Gap junction trafficking and regulation