PANTHER Gene Information   
Gene Symbol(s): act-4
Organism: Caenorhabditis elegans
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Gene Name: Actin-4
Gene ID: WBGene00000066
Protein ID: P10986
Persistent Id: PTN000233444
Alternate Ids:
ACT4_CAEEL(UniProtKB-ID) CCD83476(EMBL-CDS)
3.6.4.- {ECO:0000250|UniProtKB:P68137}(EC) NM_076440(refSeq)
ACT4(Synonym) WBGene00000066(Ensembl)
act-4(Symbol) M03F4.2a(Ensembl_TRS)
M03F4.2a(WormBase_TRS) M03F4.2a(Ensembl_PRO)
Q7YSY2(AltAccession) WBGene00000066(WormBase)
552064(GI) X16799(EMBL)
180767(GeneID) CE12358(WormBase_PRO)
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PANTHER Classification
PANTHER Family: ACTIN (PTHR11937)
PANTHER Subfamily: ACTIN-1-RELATED (PTHR11937:SF471)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process: mitotic cytokinesis
PANTHER GO-slim Cellular Component: actin cytoskeleton
PANTHER protein class: actin and actin related protein
Pathway Categories: Cadherin signaling pathway
   Filamentous F-actin
Alzheimer disease-presenilin pathway
   actin
Inflammation mediated by chemokine and cytokine signaling pathway
   F-actin
Cytoskeletal regulation by Rho GTPase
   Actin
Nicotinic acetylcholine receptor signaling pathway
   Actin
Huntington disease
   Actin

GO MF Complete: nucleotide binding, ATP binding, structural constituent of cytoskeleton, hydrolase activity
GO BP Complete: mitotic cytokinesis, actin cytoskeleton organization
GO CC Complete: striated muscle thin filament, cytoskeleton, cytoplasm, membrane raft, actin cytoskeleton
Reactome Pathways: MAPK1/MAPK3 signaling, Gap junction degradation, Signal Transduction, Innate Immune System, Signaling by Rho GTPases, Signaling by VEGF, Nervous system development, RHO GTPases Activate WASPs and WAVEs, Developmental Biology, Vesicle-mediated transport, RHOF GTPase cycle, Membrane Trafficking, Response to elevated platelet cytosolic Ca2+, EPH-ephrin mediated repulsion of cells, Fcgamma receptor (FCGR) dependent phagocytosis, Regulation of actin dynamics for phagocytic cup formation, EPHB-mediated forward signaling, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Axon guidance, Signaling by Receptor Tyrosine Kinases, Immune System, MAP2K and MAPK activation, RAF/MAP kinase cascade, L1CAM interactions, Platelet activation, signaling and aggregation, Hemostasis, MAPK family signaling cascades, Recycling pathway of L1, VEGFA-VEGFR2 Pathway, RHO GTPases Activate Formins, Cell junction organization, Cell-Cell communication, EPH-Ephrin signaling, Clathrin-mediated endocytosis, Cell-extracellular matrix interactions, Formation of annular gap junctions, RHO GTPase Effectors, Platelet degranulation , RHO GTPase cycle, RHO GTPases activate IQGAPs, Gap junction trafficking, Gap junction trafficking and regulation