PANTHER Gene Information

Gene Symbol(s):

add-2

Organism:

Caenorhabditis elegans

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Gene Name:

Adducin-related protein 2

Gene ID:

WBGene00000073

Protein ID:

Q20952

Persistent Id:

PTN000072656

Alternate Ids:

Z75953(EMBL)	AAD49860(EMBL-CDS)
F57F5.4a(Ensembl_TRS)	ADD2(Synonym)
F57F5.4a(Ensembl_PRO)	add-2(Symbol)
179647(GeneID)	F57F5.4a(WormBase_TRS)
WBGene00000073(WormBase)	CE06002(WormBase_PRO)
ADD2_CAEEL(UniProtKB-ID)	WBGene00000073(Ensembl)
10719865(GI)	NP_001041130(refSeq)
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PANTHER Classification

PANTHER Family:	ADDUCIN (PTHR10672)
PANTHER Subfamily:	ADDUCIN-RELATED PROTEIN 2 (PTHR10672:SF42)
PANTHER GO-slim Molecular Function:	actin filament binding
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	postsynaptic density cytoskeleton plasma membrane
PANTHER protein class:	non-motor actin binding protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	actin filament binding, actin binding
GO BP Complete:	-
GO CC Complete:	postsynaptic density, cytoskeleton, cytoplasm, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Signal Transduction, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Signaling by Rho GTPases, RHOD GTPase cycle, RHO GTPase cycle, Transport of small molecules, Miscellaneous transport and binding events, RHOF GTPase cycle

Orthologs

ID	Organism	Type
HUMAN\|HGNC=244\|UniProtKB=P35612	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000012032.6\|UniProtKB=A0A2J8N4B6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000005184.3\|UniProtKB=A0A2I2YDZ2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000010592.4\|UniProtKB=F7CGX1	Macaca mulatta	O
MOUSE\|MGI=MGI=87919\|UniProtKB=Q9QYB8	Mus musculus	O
RAT\|RGD=2042\|UniProtKB=Q05764	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000009076.6\|UniProtKB=F1MXA4	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000020736.4\|UniProtKB=I3L5B0	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000024568.4\|UniProtKB=A0A9L0RFJ3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000023197.4\|UniProtKB=M3XBW4	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845027938.1\|UniProtKB=A0A8I3Q364	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000011394.4\|UniProtKB=A0A5F8GGI0	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000043850.1\|UniProtKB=A0A6I8PH29	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010019291.1\|UniProtKB=A0A8V0ZA30	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000005866.4\|UniProtKB=R4GCI4	Anolis carolinensis	O
XENLA\|Gene=add2.L\|UniProtKB=A0A1L8H1E0	Xenopus laevis	O
XENLA\|Gene=add2.S\|UniProtKB=A0A1L8GS92	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-986535\|UniProtKB=A4IIR0	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000030229.1\|UniProtKB=A0A3B3HYP8	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-080718-4\|UniProtKB=F1QTE3	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015316.1\|UniProtKB=W5NDY9	lepisosteus oculatus	O
HUMAN\|HGNC=245\|UniProtKB=Q9UEY8	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000002935.7\|UniProtKB=H2R3Y3	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000025164.2\|UniProtKB=A0A2I2ZPJ2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000006233.4\|UniProtKB=A0A5K1UIG8	Macaca mulatta	O
MOUSE\|MGI=MGI=1351615\|UniProtKB=Q9QYB5	Mus musculus	O
RAT\|RGD=2043\|UniProtKB=Q62847	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000003265.6\|UniProtKB=A0A3Q1NDE1	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000010621.5\|UniProtKB=A0A4X1TEQ8	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000013629.4\|UniProtKB=A0A9L0T0N0	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000004880.6\|UniProtKB=A0A337SED7	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845028244.1\|UniProtKB=A0A8I3PX64	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000010623.4\|UniProtKB=F7DP92	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000001601.4\|UniProtKB=A0A6I8NBA3	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010020211.1\|UniProtKB=A0A8V0ZCD1	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000006070.4\|UniProtKB=G1KF70	Anolis carolinensis	O
XENLA\|Gene=add3.L\|UniProtKB=Q4KLW7	Xenopus laevis	O
XENLA\|Gene=add3.S\|UniProtKB=A0A8J0T5A2	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5923007\|UniProtKB=A0A6I8RRT6	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000006001.2\|UniProtKB=A0A3B3HJU8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000015152.2\|UniProtKB=A0A3B3HIK6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-080718-6\|UniProtKB=A0A8M1P3L7	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030131-2721\|UniProtKB=A0A2R8Q5P5	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000012377.1\|UniProtKB=W5N3N2	lepisosteus oculatus	O
HUMAN\|HGNC=243\|UniProtKB=P35611	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000015850.7\|UniProtKB=H2QP46	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000007407.3\|UniProtKB=G3QWT5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000008379.4\|UniProtKB=F7HMH8	Macaca mulatta	O
MOUSE\|MGI=MGI=87918\|UniProtKB=Q9QYC0	Mus musculus	O
RAT\|RGD=2041\|UniProtKB=Q63028	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000021128.5\|UniProtKB=E1BHK2	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000008692.5\|UniProtKB=A0A286ZR45	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000013136.4\|UniProtKB=A0A3Q2H191	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000024752.4\|UniProtKB=M3XD22	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845012015.1\|UniProtKB=A0A8I3NA95	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000003815.3\|UniProtKB=A0A5F8GU51	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000001783.3\|UniProtKB=A0A6I8NWR8	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010016011.1\|UniProtKB=A0A8V0YW97	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000005207.4\|UniProtKB=A0A803TYC2	Anolis carolinensis	O
XENLA\|Gene=add1.L\|UniProtKB=A0A8J1MQ78	Xenopus laevis	O
XENLA\|Gene=add1.S\|UniProtKB=A0A8J1LIK7	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-995030\|UniProtKB=A0A8J0T1E9	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000005724.2\|UniProtKB=H2LMC7	Oryzias latipes	O
DANRE\|Gene=add1\|UniProtKB=A0A8M9PQG8	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000011644.1\|UniProtKB=W5N114	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000009296.3\|UniProtKB=F7B9Q3	Ciona intestinalis	O
BRAFL\|Gene=LOC118414126\|UniProtKB=A0A9J7MNI9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118414726\|UniProtKB=A0A9J7L3A7	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC115924095\|UniProtKB=A0A7M7NUH2	Strongylocentrotus purpuratus	O
CAEBR\|WormBase=WBGene00041723\|UniProtKB=A8Y444	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00113134\|UniProtKB=A0A8R1YNX9	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0263391\|UniProtKB=Q02645	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP004852\|UniProtKB=Q7Q954	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC004497\|UniProtKB=D6WCE9	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_299609\|UniProtKB=E9HJ66	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_299616\|UniProtKB=E9HJ67	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW000621\|UniProtKB=B7P1C8	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG185073\|UniProtKB=T1FMD1	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG115400\|UniProtKB=T1EG79	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g204900\|UniProtKB=A7S0I0	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g99928\|UniProtKB=A7S0I1	Nematostella vectensis	O
SCHPO\|PomBase=SPBC1289.14\|UniProtKB=Q7LKY2	Schizosaccharomyces pombe	O
DICDI\|dictyBase=DDB_G0282009\|UniProtKB=Q54T47	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_74198\|UniProtKB=F0Z726	Dictyostelium purpureum	O
GOSHI\|Gene=LOC107944025\|UniProtKB=A0A1U8N645	Gossypium hirsutum	O
STRCO\|Gene_OrderedLocusName=SCO4787\|UniProtKB=Q9L0H0	Streptomyces coelicolor	O
GLOVI\|Gene=Q7NDE9_GLOVI\|UniProtKB=Q7NDE9	Gloeobacter violaceus	O
BRADU\|Gene=Q89Q13_BRADU\|UniProtKB=Q89Q13	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=Q89M14_BRADU\|UniProtKB=Q89M14	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=Q89QQ9_BRADU\|UniProtKB=Q89QQ9	Bradyrhizobium diazoefficiens	O
PSEAE\|EnsemblGenome=PA3430\|UniProtKB=Q9HYH5	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA0224\|UniProtKB=Q9I6R4	Pseudomonas aeruginosa	O