PANTHER Gene Information

Gene Symbol(s):

ADD1

Organism:

Canis lupus familiaris

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Gene Name:

Adducin 1

Gene ID:

ENSCAFG00845012015.1

Protein ID:

A0A8I3NA95

Persistent Id:

PTN001321351

Alternate Ids:

ENSCAFT00845021454(Ensembl_TRS)	ENSCAFG00845012015(Ensembl)
A0A8I3NA95_CANLF(UniProtKB-ID)	A0A8I3NA95(Synonym)
ENSCAFP00845016861(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	ADDUCIN (PTHR10672)
PANTHER Subfamily:	ALPHA-ADDUCIN (PTHR10672:SF4)
PANTHER GO-slim Molecular Function:	actin filament binding
PANTHER GO-slim Biological Process:	barbed-end actin filament capping regulation of epithelial cell differentiation positive regulation of cellular component organization positive regulation of cell development
PANTHER GO-slim Cellular Component:	adherens junction focal adhesion postsynaptic density cytoskeleton plasma membrane
PANTHER protein class:	non-motor actin binding protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	actin filament binding, structural constituent of cytoskeleton
GO BP Complete:	multicellular organism growth, positive regulation of establishment of endothelial barrier, barbed-end actin filament capping, positive regulation of adherens junction organization, erythrocyte differentiation, cytoskeleton organization, cellular response to calcium ion, in utero embryonic development, homeostasis of number of cells within a tissue, cell morphogenesis, cell volume homeostasis, hemoglobin metabolic process
GO CC Complete:	postsynaptic density, adherens junction, cytoskeleton, nuclear body, synapse, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Miscellaneous transport and binding events, Programmed Cell Death, Apoptotic execution phase, Apoptosis, Apoptotic cleavage of cellular proteins, Caspase-mediated cleavage of cytoskeletal proteins, Transport of small molecules

Orthologs

ID	Organism	Type
HUMAN\|HGNC=243\|UniProtKB=P35611	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000015850.7\|UniProtKB=H2QP46	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007407.3\|UniProtKB=G3QWT5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000008379.4\|UniProtKB=F7HMH8	Macaca mulatta	LDO
MOUSE\|MGI=MGI=87918\|UniProtKB=Q9QYC0	Mus musculus	LDO
RAT\|RGD=2041\|UniProtKB=Q63028	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000021128.5\|UniProtKB=E1BHK2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000008692.5\|UniProtKB=A0A286ZR45	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000013136.4\|UniProtKB=A0A3Q2H191	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000024752.4\|UniProtKB=M3XD22	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000003815.3\|UniProtKB=A0A5F8GU51	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000001783.3\|UniProtKB=A0A6I8NWR8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010016011.1\|UniProtKB=A0A8V0YW97	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000005207.4\|UniProtKB=A0A803TYC2	Anolis carolinensis	LDO
XENLA\|Gene=add1.L\|UniProtKB=A0A8J1MQ78	Xenopus laevis	O
XENLA\|Gene=add1.S\|UniProtKB=A0A8J1LIK7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-995030\|UniProtKB=A0A8J0T1E9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000005724.2\|UniProtKB=H2LMC7	Oryzias latipes	LDO
DANRE\|Gene=add1\|UniProtKB=A0A8M9PQG8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011644.1\|UniProtKB=W5N114	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000009296.3\|UniProtKB=F7B9Q3	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118414126\|UniProtKB=A0A9J7MNI9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118414726\|UniProtKB=A0A9J7L3A7	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC115924095\|UniProtKB=A0A7M7NUH2	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00000073\|UniProtKB=Q20952	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00041723\|UniProtKB=A8Y444	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00000072\|UniProtKB=Q9U9K0	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG14555\|UniProtKB=A8XK67	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00113134\|UniProtKB=A0A8R1YNX9	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0263391\|UniProtKB=Q02645	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004852\|UniProtKB=Q7Q954	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC004497\|UniProtKB=D6WCE9	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_299609\|UniProtKB=E9HJ66	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_299616\|UniProtKB=E9HJ67	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW000621\|UniProtKB=B7P1C8	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG185073\|UniProtKB=T1FMD1	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG115400\|UniProtKB=T1EG79	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g204900\|UniProtKB=A7S0I0	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g99928\|UniProtKB=A7S0I1	Nematostella vectensis	LDO
SCHPO\|PomBase=SPBC1289.14\|UniProtKB=Q7LKY2	Schizosaccharomyces pombe	LDO
DICDI\|dictyBase=DDB_G0282009\|UniProtKB=Q54T47	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_74198\|UniProtKB=F0Z726	Dictyostelium purpureum	LDO
GOSHI\|Gene=LOC107944025\|UniProtKB=A0A1U8N645	Gossypium hirsutum	LDO
STRCO\|Gene_OrderedLocusName=SCO4787\|UniProtKB=Q9L0H0	Streptomyces coelicolor	LDO
GLOVI\|Gene=Q7NDE9_GLOVI\|UniProtKB=Q7NDE9	Gloeobacter violaceus	LDO
BRADU\|Gene=Q89Q13_BRADU\|UniProtKB=Q89Q13	Bradyrhizobium diazoefficiens	LDO
BRADU\|Gene=Q89M14_BRADU\|UniProtKB=Q89M14	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=Q89QQ9_BRADU\|UniProtKB=Q89QQ9	Bradyrhizobium diazoefficiens	O
PSEAE\|EnsemblGenome=PA3430\|UniProtKB=Q9HYH5	Pseudomonas aeruginosa	LDO
PSEAE\|EnsemblGenome=PA0224\|UniProtKB=Q9I6R4	Pseudomonas aeruginosa	O