PANTHER Gene Information

Gene Symbol(s):

hlh-10

Organism:

Caenorhabditis elegans

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Gene Name:

Helix-loop-helix protein 10

Gene ID:

WBGene00001954

Protein ID:

Q23579

Persistent Id:

PTN001516519

Alternate Ids:

NM_073000(refSeq)	HLH10_CAEEL(UniProtKB-ID)
WBGene00001954(WormBase)	191402(GeneID)
WBGene00001954(Ensembl)	2023454620(GI)
BX284605(EMBL)	CCD69798(EMBL-CDS)
ZK682(WormBase_TRS)	CE47615(WormBase_PRO)
CeABF-1{ECO:0000303\|PubMed:11691930}(Synonym)	ZK682.4(Ensembl_TRS)
ZK682.4(Ensembl_PRO)	hlh-10{ECO:0000312\|WormBase:ZK682.4}(Symbol)
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PANTHER Classification

PANTHER Family:	BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST (PTHR23349)
PANTHER Subfamily:	HELIX-LOOP-HELIX PROTEIN 10 (PTHR23349:SF109)
PANTHER GO-slim Molecular Function:	DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process:	regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class:	basic helix-loop-helix transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, transcription corepressor activity, protein heterodimerization activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding, protein dimerization activity, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	negative regulation of transcription by RNA polymerase II, developmental process, regulation of transcription by RNA polymerase II
GO CC Complete:	nucleus, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=32322\|UniProtKB=Q7RTU7	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000049318.1\|UniProtKB=A0A2I3S988	Pan troglodytes	O
MACMU\|Ensembl=ENSMMUG00000045410.2\|UniProtKB=A0A1D5QV41	Macaca mulatta	O
MOUSE\|MGI=MGI=102934\|UniProtKB=Q64124	Mus musculus	O
RAT\|RGD=1588254\|UniProtKB=G3V8X3	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000009816.6\|UniProtKB=E1B9U0	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000034551.2\|UniProtKB=A0A287B335	Sus scrofa	O
FELCA\|Ensembl=ENSFCAG00000041246.2\|UniProtKB=A0A337SE52	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845009375.1\|UniProtKB=A0A8I3N2A5	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000047264.1\|UniProtKB=A0A6I8NTX8	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010009458.1\|UniProtKB=A0A8V0XXN0	Gallus gallus	O
CHICK\|Gene=SCX\|UniProtKB=P59101	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000012688.4\|UniProtKB=H9GJ55	Anolis carolinensis	O
XENLA\|Gene=scx.L\|UniProtKB=A5H9T7	Xenopus laevis	O
XENLA\|Gene=scx.S\|UniProtKB=C0J6N0	Xenopus laevis	O
XENTR\|Gene=scx\|UniProtKB=A0A8J0R888	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000006041.2\|UniProtKB=H2LNG5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-090806-1\|UniProtKB=A0A8N7T827	Danio rerio	O
DANRE\|Gene=scxa\|UniProtKB=A0A8M1NCA2	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000007444.1\|UniProtKB=W5MKW9	lepisosteus oculatus	O
HUMAN\|HGNC=11627\|UniProtKB=Q12870	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000030668.3\|UniProtKB=H2R966	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000015133.3\|UniProtKB=G3RGL3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000056387.1\|UniProtKB=A0A5F7ZNS1	Macaca mulatta	O
MOUSE\|MGI=MGI=104664\|UniProtKB=Q60756	Mus musculus	O
RAT\|RGD=1308464\|UniProtKB=D3ZEK9	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000005750.5\|UniProtKB=A2VE98	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000036940.3\|UniProtKB=A0A286ZU17	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000002411.3\|UniProtKB=F6VFW8	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000042662.2\|UniProtKB=A0A337S977	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845015657.1\|UniProtKB=A0A8I3RYY1	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000019526.5\|UniProtKB=A0A5F8GUD4	Monodelphis domestica	O
CHICK\|Gene=TCF15\|UniProtKB=P79782	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010013861.1\|UniProtKB=A0A8V0YNT0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000011172.3\|UniProtKB=H9GH86	Anolis carolinensis	O
XENLA\|Gene=tcf15.S\|UniProtKB=A0A8J0TZD4	Xenopus laevis	O
XENLA\|Gene=tcf15.L\|UniProtKB=Q5SE74	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-488935\|UniProtKB=Q28HQ5	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000015082.2\|UniProtKB=H2MJQ3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-980605-20\|UniProtKB=Q9YHA3	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000002219.1\|UniProtKB=W5M2H6	lepisosteus oculatus	O
MONDO\|Ensembl=ENSMODG00000043501.1\|UniProtKB=A0A5F8HBA1	Monodelphis domestica	O
CHICK\|Ensembl=ENSGALG00010009224.1\|UniProtKB=A0A8V0XWH3	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000042491.1\|UniProtKB=A0A803ST56	Anolis carolinensis	O
XENLA\|Gene=LOC108708957\|UniProtKB=A0A8J1MEL2	Xenopus laevis	O
XENLA\|Gene=LOC108708419\|UniProtKB=A0A8J0UFZ7	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000034723\|UniProtKB=A0A6I8QIC7	Xenopus tropicalis	O
DANRE\|ZFIN=ZDB-GENE-050208-498\|UniProtKB=K7DYE4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000001058.1\|UniProtKB=W5LYI5	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000000045.3\|UniProtKB=Q4H2Z7	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_126491\|UniProtKB=C3YC00	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_101984\|UniProtKB=C3ZX20	Branchiostoma floridae	O
BRAFL\|Gene=LOC118424513\|UniProtKB=A0A9J7N469	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC100894088\|UniProtKB=A0A7M7LPM9	Strongylocentrotus purpuratus	O
CAEBR\|Gene_ORFName=CBG19244\|UniProtKB=A8XV62	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00206222\|UniProtKB=A0A2A6BY93	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0053557\|UniProtKB=Q59E67	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP013406\|UniProtKB=F5HJS7	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC015754\|UniProtKB=D2A3T4	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_227979\|UniProtKB=E9HA92	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG91618\|UniProtKB=T1G863	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g199398\|UniProtKB=A7RMR1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g106073\|UniProtKB=A7S669	Nematostella vectensis	O
CRYNJ\|EnsemblGenome=CNH00430\|UniProtKB=Q5KCB3	Cryptococcus neoformans	O