PANTHER Gene Information

Gene Symbol(s):

raga-1

Organism:

Caenorhabditis elegans

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Gene Name:

GTP-binding protein

Gene ID:

WBGene00006414

Protein ID:

Q22743

Persistent Id:

PTN000136062

Alternate Ids:

BX284602(EMBL)	Q22743_CAEEL(UniProtKB-ID)
CE02361(WormBase_PRO)	T24F1(WormBase_TRS)
WBGene00006414(Ensembl)	WBGene00006414(WormBase)
3880123(GI)	Q22743(Synonym)
CAA90136(EMBL-CDS)	NM_064014(refSeq)
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PANTHER Classification

PANTHER Family:	RAS-RELATED GTP BINDING RAG/GTR YEAST (PTHR11259)
PANTHER Subfamily:	RAS-RELATED GTP-BINDING PROTEIN (PTHR11259:SF1)
PANTHER GO-slim Molecular Function:	anion binding nucleotide binding GTPase activity carbohydrate derivative binding
PANTHER GO-slim Biological Process:	positive regulation of TORC1 signaling cellular response to starvation negative regulation of autophagy
PANTHER GO-slim Cellular Component:	nucleus catalytic complex lysosome
PANTHER protein class:	small GTPase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	GTP binding, GTPase activity
GO BP Complete:	multicellular organismal reproductive process, positive regulation of TORC1 signaling, determination of adult lifespan, negative regulation of autophagy, cellular response to starvation, positive regulation of TOR signaling, positive regulation of multicellular organism growth
GO CC Complete:	nucleus, Gtr1-Gtr2 GTPase complex, lysosome

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Amino acids regulate mTORC1, mTORC1-mediated signalling, Cellular responses to stress, Signal Transduction, MTOR signalling, Intracellular signaling by second messengers, RNA Polymerase II Transcription, Macroautophagy, Autophagy, Transcriptional Regulation by TP53, Energy dependent regulation of mTOR by LKB1-AMPK, Regulation of PTEN gene transcription, Generic Transcription Pathway, Gene expression (Transcription), Cellular response to starvation, TP53 Regulates Metabolic Genes, Cellular responses to stimuli, PTEN Regulation, PIP3 activates AKT signaling

Orthologs

ID	Organism	Type
HUMAN\|HGNC=19901\|UniProtKB=Q5VZM2	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000021955.5\|UniProtKB=H2R4Q2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000011501.3\|UniProtKB=G3R786	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000017635.4\|UniProtKB=H9EUC2	Macaca mulatta	O
MOUSE\|MGI=MGI=3038613\|UniProtKB=Q6NTA4	Mus musculus	O
RAT\|RGD=619805\|UniProtKB=Q63487	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000012980.6\|UniProtKB=G5E5G3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000037228.3\|UniProtKB=I3LK13	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000006020.4\|UniProtKB=F7A8T2	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000013932.6\|UniProtKB=M3WJR9	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845030377.1\|UniProtKB=A0A8I3QXU8	Canis lupus familiaris	O
HUMAN\|HGNC=16963\|UniProtKB=Q7L523	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020798.4\|UniProtKB=H2QX14	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000021937.2\|UniProtKB=G3S7I4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000018395.4\|UniProtKB=G7NFY4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1915691\|UniProtKB=Q80X95	Mus musculus	LDO
RAT\|RGD=619804\|UniProtKB=Q63486	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000038064.3\|UniProtKB=E1BGP6	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000033543\|UniProtKB=Q3SX43	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000005174.4\|UniProtKB=F2Z5Q5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000005729.4\|UniProtKB=A0A3Q2H8X1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000022742.3\|UniProtKB=M3X4R7	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845014185.1\|UniProtKB=A0A8I3NIS5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000011337.4\|UniProtKB=F6W377	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000022007.3\|UniProtKB=F7F5L1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010011898.1\|UniProtKB=A0A8V0YF42	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000006339.3\|UniProtKB=H9GBB0	Anolis carolinensis	LDO
XENLA\|Gene=rraga.S\|UniProtKB=Q6IP38	Xenopus laevis	LDO
XENLA\|Gene=rraga.L\|UniProtKB=A0AUU5	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5756345\|UniProtKB=Q6GLA8	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009278.2\|UniProtKB=H2LZR3	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-4083\|UniProtKB=Q7ZUI2	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000014979.1\|UniProtKB=W5NCT3	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007876.3\|UniProtKB=F6TGX2	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_123649\|UniProtKB=C3ZF20	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC588042\|UniProtKB=A0A7M7HIG0	Strongylocentrotus purpuratus	LDO
CAEBR\|WormBase=WBGene00025891\|UniProtKB=A8WT67	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00272452\|UniProtKB=A0A2A6BZ21	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0037647\|UniProtKB=Q9VHJ4	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002991\|UniProtKB=Q7QD78	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC010924\|UniProtKB=D6WMU5	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_301559\|UniProtKB=E9G9U2	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW011735\|UniProtKB=B7Q6G8	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG78026\|UniProtKB=T1G369	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g188861\|UniProtKB=A7SEE4	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG49549\|UniProtKB=B3RIE8	Trichoplax adhaerens	LDO
YEAST\|SGD=S000004590\|UniProtKB=Q00582	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR446W\|UniProtKB=Q752X7	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000174018\|UniProtKB=A0A1D8PI64	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_A10098g\|UniProtKB=Q6CHD2	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_08796\|UniProtKB=Q5ASD4	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G09650\|UniProtKB=Q4WUU0	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU01099\|UniProtKB=Q1K878	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_02002\|UniProtKB=A7E9M2	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_11119\|UniProtKB=Q0UAU5	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC337.13c\|UniProtKB=O74824	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_00457\|UniProtKB=B6JVP2	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNA07810\|UniProtKB=Q5KN41	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_11426\|UniProtKB=A0A0D1EBS2	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_04801\|UniProtKB=E3K443	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_92709\|UniProtKB=F4PEG8	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_178770\|UniProtKB=C4LUU1	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0288701\|UniProtKB=Q54IK1	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_35824\|UniProtKB=F0ZPW4	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_13_1560\|UniProtKB=Q4QFZ8	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.02.0820\|UniProtKB=Q386H9	Trypanosoma brucei	LDO
PARTE\|EnsemblGenome=GSPATT00000262001\|UniProtKB=Q6BFW9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000846001\|UniProtKB=Q3SDS6	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_261527\|UniProtKB=B8BVH8	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GWU9_PHYRM\|UniProtKB=H3GWU9	Phytophthora ramorum	LDO