PANTHER Gene Information

Gene Symbol(s):

Tb11.02.0820

Organism:

Trypanosoma brucei

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Gene Name:

Ras-family member, GTP-binding protein, putative

Gene ID:

Tb11.02.0820

Protein ID:

Q386H9

Persistent Id:

PTN002258413

Alternate Ids:

71754999(GI)	EAN79302(EMBL-CDS)
3664173(GeneID)	XP_828414(refSeq)
Q386H9_TRYB2(UniProtKB-ID)	Q386H9(Synonym)
CH464491(EMBL)
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PANTHER Classification

PANTHER Family:	RAS-RELATED GTP BINDING RAG/GTR YEAST (PTHR11259)
PANTHER Subfamily:	RAS-RELATED GTP-BINDING PROTEIN (PTHR11259:SF1)
PANTHER GO-slim Molecular Function:	anion binding nucleotide binding GTPase activity carbohydrate derivative binding
PANTHER GO-slim Biological Process:	positive regulation of TORC1 signaling cellular response to starvation negative regulation of autophagy
PANTHER GO-slim Cellular Component:	nucleus catalytic complex lysosome
PANTHER protein class:	small GTPase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	GTP binding, GTPase activity
GO BP Complete:	positive regulation of TORC1 signaling, negative regulation of autophagy, cellular response to starvation
GO CC Complete:	nucleus, Gtr1-Gtr2 GTPase complex, lysosome

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=19901\|UniProtKB=Q5VZM2	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000021955.5\|UniProtKB=H2R4Q2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000011501.3\|UniProtKB=G3R786	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000017635.4\|UniProtKB=H9EUC2	Macaca mulatta	O
MOUSE\|MGI=MGI=3038613\|UniProtKB=Q6NTA4	Mus musculus	O
RAT\|RGD=619805\|UniProtKB=Q63487	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000012980.6\|UniProtKB=G5E5G3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000037228.3\|UniProtKB=I3LK13	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000006020.4\|UniProtKB=F7A8T2	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000013932.6\|UniProtKB=M3WJR9	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845030377.1\|UniProtKB=A0A8I3QXU8	Canis lupus familiaris	O
HUMAN\|HGNC=16963\|UniProtKB=Q7L523	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020798.4\|UniProtKB=H2QX14	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000021937.2\|UniProtKB=G3S7I4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000018395.4\|UniProtKB=G7NFY4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1915691\|UniProtKB=Q80X95	Mus musculus	LDO
RAT\|RGD=619804\|UniProtKB=Q63486	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000038064.3\|UniProtKB=E1BGP6	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000033543\|UniProtKB=Q3SX43	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000005174.4\|UniProtKB=F2Z5Q5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000005729.4\|UniProtKB=A0A3Q2H8X1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000022742.3\|UniProtKB=M3X4R7	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845014185.1\|UniProtKB=A0A8I3NIS5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000011337.4\|UniProtKB=F6W377	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000022007.3\|UniProtKB=F7F5L1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010011898.1\|UniProtKB=A0A8V0YF42	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000006339.3\|UniProtKB=H9GBB0	Anolis carolinensis	LDO
XENLA\|Gene=rraga.S\|UniProtKB=Q6IP38	Xenopus laevis	LDO
XENLA\|Gene=rraga.L\|UniProtKB=A0AUU5	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5756345\|UniProtKB=Q6GLA8	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009278.2\|UniProtKB=H2LZR3	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-4083\|UniProtKB=Q7ZUI2	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000014979.1\|UniProtKB=W5NCT3	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007876.3\|UniProtKB=F6TGX2	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_123649\|UniProtKB=C3ZF20	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC588042\|UniProtKB=A0A7M7HIG0	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00006414\|UniProtKB=Q22743	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00025891\|UniProtKB=A8WT67	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00272452\|UniProtKB=A0A2A6BZ21	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0037647\|UniProtKB=Q9VHJ4	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002991\|UniProtKB=Q7QD78	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC010924\|UniProtKB=D6WMU5	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_301559\|UniProtKB=E9G9U2	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW011735\|UniProtKB=B7Q6G8	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG78026\|UniProtKB=T1G369	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g188861\|UniProtKB=A7SEE4	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG49549\|UniProtKB=B3RIE8	Trichoplax adhaerens	LDO
YEAST\|SGD=S000004590\|UniProtKB=Q00582	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR446W\|UniProtKB=Q752X7	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000174018\|UniProtKB=A0A1D8PI64	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_A10098g\|UniProtKB=Q6CHD2	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_08796\|UniProtKB=Q5ASD4	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G09650\|UniProtKB=Q4WUU0	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU01099\|UniProtKB=Q1K878	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_02002\|UniProtKB=A7E9M2	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_11119\|UniProtKB=Q0UAU5	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC337.13c\|UniProtKB=O74824	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_00457\|UniProtKB=B6JVP2	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNA07810\|UniProtKB=Q5KN41	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_11426\|UniProtKB=A0A0D1EBS2	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_04801\|UniProtKB=E3K443	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_92709\|UniProtKB=F4PEG8	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_178770\|UniProtKB=C4LUU1	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0288701\|UniProtKB=Q54IK1	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_35824\|UniProtKB=F0ZPW4	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_13_1560\|UniProtKB=Q4QFZ8	Leishmania major	LDO
PARTE\|EnsemblGenome=GSPATT00000262001\|UniProtKB=Q6BFW9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000846001\|UniProtKB=Q3SDS6	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_261527\|UniProtKB=B8BVH8	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GWU9_PHYRM\|UniProtKB=H3GWU9	Phytophthora ramorum	LDO