PANTHER Gene Information

Gene Symbol(s):

PPARD

Organism:

Canis lupus familiaris

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Gene Name:

Peroxisome proliferator-activated receptor delta

Gene ID:

ENSCAFG00030015370

Protein ID:

Q0ZAQ8

Persistent Id:

PTN000638197

Alternate Ids:

ENSCAFG00040015805(Ensembl)	115502562(GI)
XM_005627075(refSeq)	PPARD_CANLF(UniProtKB-ID)
PPARD(Symbol)	Peroxisome proliferator-activated receptor beta(Synonym)
CHEMBL1932904(ChEMBL)	ENSCAFT00040029299(Ensembl_TRS)
481756(GeneID)	ENSCAFP00040025452(Ensembl_PRO)
DQ648277(EMBL)	ABG36929(EMBL-CDS)
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PANTHER Classification

PANTHER Family:	NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily:	PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA (PTHR24082:SF15)
PANTHER GO-slim Molecular Function:	DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding signaling receptor activity
PANTHER GO-slim Biological Process:	negative regulation of transcription by RNA polymerase II negative regulation of inflammatory response regulation of lipid metabolic process cell differentiation regulation of localization fatty acid metabolic process hormone-mediated signaling pathway positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class:	C4 zinc finger nuclear receptor

Pathway Categories:

Wnt signaling pathway

Wnt Target Genes

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	nuclear receptor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific
GO BP Complete:	negative regulation of transcription by RNA polymerase II, negative regulation of inflammatory response, cell differentiation, negative regulation of cholesterol storage, positive regulation of transcription by RNA polymerase II, positive regulation of fatty acid metabolic process, fatty acid metabolic process, hormone-mediated signaling pathway
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Gene expression (Transcription), Generic Transcription Pathway, Nuclear Receptor transcription pathway, Signaling by Retinoic Acid, Metabolism of lipids, Signaling by Nuclear Receptors, Signal Transduction, Pyruvate metabolism, Pyruvate metabolism and Citric Acid (TCA) cycle, Carnitine metabolism, The citric acid (TCA) cycle and respiratory electron transport, Fatty acid metabolism, RNA Polymerase II Transcription, Metabolism, Regulation of pyruvate dehydrogenase (PDH) complex

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9235\|UniProtKB=Q03181	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000018082.6\|UniProtKB=H2R2N3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000016781.3\|UniProtKB=G3RKU1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000015904.4\|UniProtKB=G7MRT0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=101884\|UniProtKB=P35396	Mus musculus	LDO
RAT\|RGD=3370\|UniProtKB=Q99ND3	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000017542.6\|UniProtKB=A4IFL4	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000001539.5\|UniProtKB=A0A8X9AEJ2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000008227.4\|UniProtKB=F6WAT9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000025234.4\|UniProtKB=A0A2I2U3X3	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000013778.4\|UniProtKB=F6TVN5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000050623.1\|UniProtKB=A0A6I8PFN0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010027545.1\|UniProtKB=A0A3Q3AXA2	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000002228.4\|UniProtKB=G1KAH9	Anolis carolinensis	LDO
XENLA\|Gene=ppard\|UniProtKB=P37233	Xenopus laevis	O
XENLA\|Gene=ppard.S\|UniProtKB=A0A8J1MB60	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-481495\|UniProtKB=A0A6I8SH51	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000006636.2\|UniProtKB=A0A3B3HFH4	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-990415-212\|UniProtKB=F8W3D2	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-000112-47\|UniProtKB=A9C4A5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011628.1\|UniProtKB=W5N0Y1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000013188.2\|UniProtKB=Q4H2X6	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118405726\|UniProtKB=A0A9J7HKH0	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC579208\|UniProtKB=A0A7M7RDK4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC576339\|UniProtKB=A0A7M7NVX1	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003601\|UniProtKB=Q10902	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG04060\|UniProtKB=A8WW43	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003606\|UniProtKB=Q20765	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028390\|UniProtKB=A8X108	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00004786\|UniProtKB=P41830	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038735\|UniProtKB=A8XVU5	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG19536\|UniProtKB=A8XVU6	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG17178\|UniProtKB=A8XQM1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003675\|UniProtKB=Q9XUK7	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13679\|UniProtKB=A8XIG9	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00029816\|UniProtKB=A8X5D8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00272173\|UniProtKB=A0A2A6BTX7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0000568\|UniProtKB=P13055	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029560\|UniProtKB=A0A453Z0D2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003935\|UniProtKB=D6WHQ0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC031236\|UniProtKB=A0A139WCF5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_205205\|UniProtKB=E9FSB9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020016\|UniProtKB=B7Q233	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG81466\|UniProtKB=T1G4E6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67484\|UniProtKB=T1FZ14	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67463\|UniProtKB=T1FZ12	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g108851\|UniProtKB=A7S8G8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g101676\|UniProtKB=A7S286	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g152310\|UniProtKB=A7TAF5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g149683\|UniProtKB=A7T846	Nematostella vectensis	O