PANTHER Gene Information   
Gene Symbol(s): Ppard
Organism: Rattus norvegicus
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Gene Name: Peroxisome proliferator-activated receptor delta
Gene ID: 3370
Protein ID: Q99ND3
Persistent Id: PTN000638194
Alternate Ids:
Q99ND3_RAT(UniProtKB-ID) XM_006256167(refSeq)
25682(GeneID) ENSRNOT00000042539(Ensembl_TRS)
3370(RGD) ENSRNOP00000045974(Ensembl_PRO)
ENSRNOG00000000503(Ensembl) 564397174(GI)
Q99ND3(Synonym)
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PANTHER Classification
PANTHER Family: NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily: PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA (PTHR24082:SF15)  
PANTHER GO-slim Molecular Function: DNA-binding transcription repressor activity, RNA polymerase II-specific
RNA polymerase II cis-regulatory region sequence-specific DNA binding
signaling receptor activity
PANTHER GO-slim Biological Process: negative regulation of transcription by RNA polymerase II
negative regulation of inflammatory response
regulation of lipid metabolic process
cell differentiation
regulation of localization
fatty acid metabolic process
hormone-mediated signaling pathway
positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class: C4 zinc finger nuclear receptor
Pathway Categories: Wnt signaling pathway
   Wnt Target Genes

GO MF Complete: NF-kappaB binding, DNA binding, DNA-binding transcription factor activity, zinc ion binding, linoleic acid binding, fatty acid binding, nuclear receptor activity, metal ion binding, lipid binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, sequence-specific double-stranded DNA binding, transcription coactivator binding
GO BP Complete: decidualization, fatty acid beta-oxidation, response to glucose, negative regulation of collagen biosynthetic process, wound healing, epithelial cell proliferation, fatty acid transport, negative regulation of cell growth, positive regulation of DNA-templated transcription, apoptotic process, energy homeostasis, cellular response to hypoxia, regulation of epithelial cell proliferation, cellular response to nutrient levels, fatty acid oxidation, negative regulation of myoblast differentiation, positive regulation of gene expression, negative regulation of epithelial cell proliferation, positive regulation of myoblast proliferation, response to activity, cell-substrate adhesion, positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction, cell population proliferation, negative regulation of miRNA transcription, apoptotic signaling pathway, axon ensheathment, vasodilation, placenta development, proteoglycan metabolic process, negative regulation of transcription by RNA polymerase II, heart development, phosphatidylinositol 3-kinase/protein kinase B signal transduction, positive regulation of fatty acid oxidation, negative regulation of smooth muscle cell proliferation, fat cell proliferation, positive regulation of fat cell proliferation, negative regulation of smooth muscle cell migration, positive regulation of insulin secretion involved in cellular response to glucose stimulus, intracellular receptor signaling pathway, keratinocyte migration, keratinocyte proliferation, phospholipid biosynthetic process, regulation of fat cell differentiation, embryo implantation, regulation of cell population proliferation, positive regulation of skeletal muscle tissue regeneration, regulation of transcription by RNA polymerase II, adipose tissue development, cellular response to lipopolysaccharide, positive regulation of epidermis development, negative regulation of apoptotic process, lipid metabolic process, cell differentiation, response to vitamin A, regulation of skeletal muscle satellite cell proliferation
GO CC Complete: nucleus, chromatin
Reactome Pathways: Pyruvate metabolism, Signaling by Retinoic Acid, Carnitine metabolism, Signal Transduction, Fatty acid metabolism, Pyruvate metabolism and Citric Acid (TCA) cycle, RNA Polymerase II Transcription, Metabolism, Nuclear Receptor transcription pathway, The citric acid (TCA) cycle and respiratory electron transport, Regulation of pyruvate dehydrogenase (PDH) complex, Metabolism of lipids, Signaling by Nuclear Receptors, Generic Transcription Pathway, Gene expression (Transcription)