PANTHER Gene Information   
Gene Symbol(s): UBE2D2
Organism: Canis lupus familiaris
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Gene Name: Ubiquitin conjugating enzyme E2 D2
Gene ID: ENSCAFG00845000981.1
Protein ID: A0A8I3MJ82
Persistent Id: PTN000631239
Alternate Ids:
ENSCAFP00845001321(Ensembl_PRO) A0A8I3MJ82(Synonym)
ENSCAFT00845001673(Ensembl_TRS) ENSCAFG00845000981(Ensembl)
A0A8I3MJ82_CANLF(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: UBIQUITIN-CONJUGATING ENZYME E2 (PTHR24068)
PANTHER Subfamily: UBIQUITIN-CONJUGATING ENZYME E2D N-TERMINAL LIKE 1-RELATED (PTHR24068:SF532)  
PANTHER GO-slim Molecular Function: ubiquitin conjugating enzyme activity
ubiquitin protein ligase binding
PANTHER GO-slim Biological Process: ubiquitin-dependent protein catabolic process
protein polyubiquitination
PANTHER GO-slim Cellular Component: nucleus
ubiquitin ligase complex
PANTHER protein class: ubiquitin-protein ligase
Pathway Categories: Ubiquitin proteasome pathway
   Ubiquitin-conjugating enzyme E2
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP binding, ubiquitin protein ligase activity, ubiquitin conjugating enzyme activity
GO BP Complete: protein K48-linked ubiquitination, ubiquitin-dependent protein catabolic process, protein autoubiquitination
GO CC Complete: nucleus, protein-containing complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Protein ubiquitination, Signaling by CSF3 (G-CSF), FCERI mediated NF-kB activation, Toll-like Receptor Cascades, Inactivation of CSF3 (G-CSF) signaling, Death Receptor Signaling, Toll Like Receptor 4 (TLR4) Cascade, Immune System, Class I MHC mediated antigen processing & presentation, Antigen processing: Ubiquitination & Proteasome degradation, Neddylation, Synthesis of active ubiquitin: roles of E1 and E2 enzymes, E3 ubiquitin ligases ubiquitinate target proteins, IKK complex recruitment mediated by RIP1, Metabolism of proteins, TRIF(TICAM1)-mediated TLR4 signaling , Cellular response to hypoxia, Fc epsilon receptor (FCERI) signaling, Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha, CLEC7A (Dectin-1) signaling, Peroxisomal protein import, TNF signaling, Adaptive Immune System, Downstream TCR signaling, Innate Immune System, Signal Transduction, TCR signaling, Protein localization, Cytokine Signaling in Immune system, Cellular responses to stimuli, MyD88-independent TLR4 cascade , Post-translational protein modification, Regulation of TNFR1 signaling, C-type lectin receptors (CLRs), Cellular responses to stress

Orthologs