PANTHER Gene Information

Gene Symbol(s):

zgc:55886

Organism:

Danio rerio

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Gene Name:

Ubiquitin-conjugating enzyme E2 D2

Gene ID:

ZDB-GENE-120312-1

Protein ID:

Q7ZUK1

Persistent Id:

PTN000631249

Alternate Ids:

41351441(GI)	ENSDART00000063837(Ensembl_TRS)
ENSDARG00000043484(Ensembl)	AAH48896(EMBL-CDS)
Q7ZUK1_DANRE(UniProtKB-ID)	Q7ZUK1(Synonym)
NM_200959(refSeq)	BC065678(EMBL)
393934(GeneID)	ZDB-GENE-120312-1(ZFIN)
ENSDARP00000063836(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	UBIQUITIN-CONJUGATING ENZYME E2 (PTHR24068)
PANTHER Subfamily:	UBIQUITIN-CONJUGATING ENZYME E2D N-TERMINAL LIKE 1-RELATED (PTHR24068:SF532)
PANTHER GO-slim Molecular Function:	ubiquitin conjugating enzyme activity ubiquitin protein ligase binding
PANTHER GO-slim Biological Process:	ubiquitin-dependent protein catabolic process protein polyubiquitination
PANTHER GO-slim Cellular Component:	nucleus ubiquitin ligase complex
PANTHER protein class:	ubiquitin-protein ligase

Pathway Categories:

Ubiquitin proteasome pathway

Ubiquitin-conjugating enzyme E2

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	nucleotide binding, ATP binding, ubiquitin conjugating enzyme activity, transferase activity
GO BP Complete:	protein polyubiquitination, negative regulation of smoothened signaling pathway, ubiquitin-dependent protein catabolic process
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Adaptive Immune System, Death Receptor Signaling, Neddylation, Protein ubiquitination, Metabolism of proteins, Signal Transduction, Antigen processing: Ubiquitination & Proteasome degradation, Immune System, TNF signaling, Class I MHC mediated antigen processing & presentation, Post-translational protein modification, Regulation of TNFR1 signaling, Synthesis of active ubiquitin: roles of E1 and E2 enzymes

Orthologs

ID	Organism	Type
MOUSE\|MGI=MGI=3646570\|UniProtKB=A2AFH1	Mus musculus	LDO
MOUSE\|MGI=MGI=1922347\|UniProtKB=A2AFH2	Mus musculus	LDO
RAT\|RGD=41199544\|UniProtKB=D3ZL88	Rattus norvegicus	LDO
HORSE\|Ensembl=ENSECAG00000026911.4\|UniProtKB=A0A9L0TG06	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845000981.1\|UniProtKB=A0A8I3MJ82	Canis lupus familiaris	LDO
XENLA\|Gene=ube2d3.S\|UniProtKB=A0A8J1M3J5	Xenopus laevis	LDO
HUMAN\|HGNC=12475\|UniProtKB=P62837	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000017303.6\|UniProtKB=A0A2I3S6N5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000001368.3\|UniProtKB=A0A2I2ZGC8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000062143.1\|UniProtKB=A0A5F8A332	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1930715\|UniProtKB=P62838	Mus musculus	LDO
RAT\|RGD=1591897\|UniProtKB=P62839	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000004161\|UniProtKB=Q1RMX2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000012469.2\|UniProtKB=A0A4X1W2Y5	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000037699.3\|UniProtKB=A0A8W4FRB3	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000036711.3\|UniProtKB=A0A5G2R1D9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000026911.4\|UniProtKB=A0A9L0TG06	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000022060.4\|UniProtKB=M3WU76	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845000981.1\|UniProtKB=A0A8I3MJ82	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000049776.1\|UniProtKB=A0A5F8HBV9	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000040467.1\|UniProtKB=A0A6I8P7I3	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010011952.1\|UniProtKB=A0A8V0YFD9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000002183.4\|UniProtKB=G1KAB3	Anolis carolinensis	LDO
XENLA\|Gene=ube2d2\|UniProtKB=P62840	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000026032.1\|UniProtKB=A0A3B3I5T7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000009695.2\|UniProtKB=H2M178	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000012054.1\|UniProtKB=W5N2H5	lepisosteus oculatus	LDO
STRPU\|EnsemblGenome=LOC575665\|UniProtKB=A0A7M7LP02	Strongylocentrotus purpuratus	O
TRIAD\|EnsemblGenome=TriadG33263\|UniProtKB=B3SCF2	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG33233\|UniProtKB=B3SCE8	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_17710\|UniProtKB=A9UR38	Monosiga brevicollis	O
EMENI\|EnsemblGenome=ANIA_00883\|UniProtKB=Q5BEZ7	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G15570\|UniProtKB=Q4WRP6	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU07665\|UniProtKB=Q7S9N5	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_06530\|UniProtKB=Q0UNY4	Phaeosphaeria nodorum	O
CRYNJ\|EnsemblGenome=CNA02640\|UniProtKB=Q5KPI9	Cryptococcus neoformans	O
BATDJ\|Gene_ORFName=BATDEDRAFT_26696\|UniProtKB=F4P874	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_22905\|UniProtKB=F4NW55	Batrachochytrium dendrobatidis	O
YEAST\|SGD=S000002466\|UniProtKB=P15732	Saccharomyces cerevisiae	O
YEAST\|SGD=S000000286\|UniProtKB=P15731	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AER173C\|UniProtKB=Q756T0	Eremothecium gossypii	O
CANAL\|CGD=CAL0000178162\|UniProtKB=A0A1D8PU40	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_D15312g\|UniProtKB=Q6C907	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_02761\|UniProtKB=Q5B9M0	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G06030\|UniProtKB=Q4WWI8	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02289\|UniProtKB=Q7RVS7	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_11173\|UniProtKB=A7F0Q4	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_02749\|UniProtKB=Q0UZR5	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC119.02\|UniProtKB=P46595	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_04573\|UniProtKB=B6K767	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CND02120\|UniProtKB=Q5KIQ6	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNF02760\|UniProtKB=Q5KF72	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_00982\|UniProtKB=A0A0D1E680	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_02279\|UniProtKB=E3JXP3	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_14888\|UniProtKB=F4PEG9	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_070750\|UniProtKB=C4M5T2	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0284865\|UniProtKB=Q94490	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_48481\|UniProtKB=F0ZPB2	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0290547\|UniProtKB=Q54FX4	Dictyostelium discoideum	O
LEIMA\|EnsemblGenome=LMJF_35_1300\|UniProtKB=Q9GNC1	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.5.1000\|UniProtKB=Q57W45	Trypanosoma brucei	O
GIAIC\|Gene_ORFName=GL50803_0015252\|UniProtKB=A0A644F7I8	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_191220\|UniProtKB=A2EFK5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_043860\|UniProtKB=A2E0E6	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_153580\|UniProtKB=A2EPR3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_467860\|UniProtKB=A2E0M6	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_257610\|UniProtKB=A2F4E2	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_076890\|UniProtKB=A2D9T6	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_1203900\|UniProtKB=Q8I607	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00013520001\|UniProtKB=A0D4V6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00004931001\|UniProtKB=A0BJ41	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000658001\|UniProtKB=A0BUC8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00039052001\|UniProtKB=A0CVS4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00038076001\|UniProtKB=A0CFR8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00007512001\|UniProtKB=A0CH05	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00006096001\|UniProtKB=A0C0C6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002619001\|UniProtKB=A0DQA2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00012058001\|UniProtKB=A0D0D9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00003257001\|UniProtKB=A0DZ21	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00031081001\|UniProtKB=A0BQN5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00013765001\|UniProtKB=A0D5L8	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_22432\|UniProtKB=B8C0C0	Thalassiosira pseudonana	O
PHYRM\|Gene=H3G8P2_PHYRM\|UniProtKB=H3G8P2	Phytophthora ramorum	O
PHYRM\|Gene=H3HAQ5_PHYRM\|UniProtKB=H3HAQ5	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_16g693700v5\|UniProtKB=A8JBJ3	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00089p00096280\|UniProtKB=W1P1R2	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_53G00060\|UniProtKB=A0A0K9NWT1	Zostera marina	O
MUSAM\|EnsemblGenome=Ma01_g09760\|UniProtKB=A0A804HS88	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma09_g28520\|UniProtKB=A0A804KPP2	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma09_g12320\|UniProtKB=A0A804KIS4	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma03_g11680\|UniProtKB=A0A804IB03	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma09_g28520\|UniProtKB=A0A804KPP2	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_031414mg\|UniProtKB=K3ZXT2	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3002G155500\|UniProtKB=C5X897	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb309020\|UniProtKB=B4FCQ9	Zea mays	O
SETIT\|EnsemblGenome=SETIT_019237mg\|UniProtKB=K3YY87	Setaria italica	O
MAIZE\|EnsemblGenome=Zm00001eb097550\|UniProtKB=B6U4K0	Zea mays	O
ORYSJ\|EnsemblGenome=Os09g0293400\|UniProtKB=Q69JN7	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_4g27430v3\|UniProtKB=I1IP59	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0471520\|UniProtKB=A0A8I6XP97	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS5D02G181400\|UniProtKB=A0A3B6MQQ7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G174300\|UniProtKB=A0A3B6LL01	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G177100\|UniProtKB=A0A3B6KHB9	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_025412\|UniProtKB=A0A1U7Z3R7	Nelumbo nucifera	O
NELNU\|Gene=LOC104609421\|UniProtKB=A0A1U8B034	Nelumbo nucifera	O
PRUPE\|EnsemblGenome=PRUPE_1G008300\|UniProtKB=A0A251QRV4	Prunus persica	O
NELNU\|Gene=LOC104594343\|UniProtKB=A0A1U7ZWL5	Nelumbo nucifera	O
TOBAC\|Gene=LOC107788577\|UniProtKB=A0A1S3ZMY8	Nicotiana tabacum	O
EUCGR\|EnsemblGenome=EUGRSUZ_E04235\|UniProtKB=A0A059CB82	Eucalyptus grandis	O
THECC\|EnsemblGenome=TCM_034533\|UniProtKB=A0A061FFI9	Theobroma cacao	O
POPTR\|Gene_ORFName=POPTR_017G055300\|UniProtKB=A0A3N7G574	Populus trichocarpa	O
RICCO\|Gene_ORFName=RCOM_1019510\|UniProtKB=B9RWH5	Ricinus communis	O
PRUPE\|EnsemblGenome=PRUPE_4G150600\|UniProtKB=M5X5F5	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_187468\|UniProtKB=D8SFW4	Selaginella moellendorffii	O
MARPO\|EnsemblGenome=MARPO_0140s0024\|UniProtKB=A0A2R6W6L2	Marchantia polymorpha	O