PANTHER Gene Information

Gene Symbol(s):

TRIM3

Organism:

Canis lupus familiaris

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Gene Name:

RING-type E3 ubiquitin transferase

Gene ID:

ENSCAFG00845008173.1

Protein ID:

A0A8I3RVW6

Persistent Id:

PTN000715142

Alternate Ids:

ENSCAFT00845014376(Ensembl_TRS)	XP_534038(refSeq)
ENSCAFG00845008173(Ensembl)	A0A8I3RVW6(Synonym)
ENSCAFP00845011134(Ensembl_PRO)	73988285(GI)
A0A8I3RVW6_CANLF(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED (PTHR24104)
PANTHER Subfamily:	TRIPARTITE MOTIF-CONTAINING PROTEIN 3 (PTHR24104:SF21)
PANTHER GO-slim Molecular Function:	ubiquitin protein ligase activity
PANTHER GO-slim Biological Process:	protein polyubiquitination proteasome-mediated ubiquitin-dependent protein catabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	ubiquitin-protein ligase

Pathway Categories:

Alzheimer disease-presenilin pathway

Tripartite motif-containing protein 3

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	zinc ion binding, identical protein binding, ubiquitin protein ligase activity
GO BP Complete:	positive regulation of toll-like receptor 3 signaling pathway, proteasome-mediated ubiquitin-dependent protein catabolic process, protein polyubiquitination, neural precursor cell proliferation, protein K63-linked ubiquitination
GO CC Complete:	Golgi apparatus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=10064\|UniProtKB=O75382	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000013289.3\|UniProtKB=G3RBV0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000007728.4\|UniProtKB=F7C974	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1860040\|UniProtKB=Q9R1R2	Mus musculus	LDO
RAT\|RGD=70074\|UniProtKB=O70277	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000003565.5\|UniProtKB=A7MB36	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000059302.1\|UniProtKB=A0A287B897	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000056285.1\|UniProtKB=A0A9L0TCR6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000004634.6\|UniProtKB=A0A2I2U851	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000018582.4\|UniProtKB=F7FDA8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000001409.3\|UniProtKB=F7D344	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010001617.1\|UniProtKB=A0A8V0X2Y8	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010088.4\|UniProtKB=H9GFZ1	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000015325.3\|UniProtKB=H9GM75	Anolis carolinensis	LDO
XENLA\|Gene=trim3.S\|UniProtKB=A0A8J1MCR1	Xenopus laevis	LDO
XENLA\|Gene=trim3.L\|UniProtKB=A0A1L8HJV3	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5826034\|UniProtKB=F6TSI0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000003504.2\|UniProtKB=A0A3B3IML7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-080522-4\|UniProtKB=E7F1U3	Danio rerio	LDO
ORYLA\|Ensembl=ENSORLG00000004188.2\|UniProtKB=A0A3B3HRZ8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-070112-1132\|UniProtKB=A0A8M2B1X4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000008640.1\|UniProtKB=W5MQ45	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000012056.2\|UniProtKB=F6Z0X9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000005321.1\|UniProtKB=F7BPN8	Ciona intestinalis	O
BRAFL\|Gene=LOC118413625\|UniProtKB=A0A9J7KYW4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427258\|UniProtKB=A0A9J7M2J8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422926\|UniProtKB=A0A9J7N258	Branchiostoma floridae	O
BRAFL\|Gene=LOC118407546\|UniProtKB=A0A9J7HR11	Branchiostoma floridae	O
BRAFL\|Gene=LOC118432513\|UniProtKB=A0A9J7MFU8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118408724\|UniProtKB=A0A9J7KL64	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431812\|UniProtKB=A0A9J7ME97	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431520\|UniProtKB=A0A9J7MEP0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118416255\|UniProtKB=A0A9J7L6V8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118423263\|UniProtKB=A0A9J7N2M2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118419218\|UniProtKB=A0A9J7LEP1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422507\|UniProtKB=A0A9J7LQ32	Branchiostoma floridae	O
BRAFL\|Gene=LOC118412317\|UniProtKB=A0A9J7MKJ9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118420452\|UniProtKB=A0A9J7MVQ0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418771\|UniProtKB=A0A9J7LD99	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC592222\|UniProtKB=A0A7M7NKF8	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00003559\|UniProtKB=P34611	Caenorhabditis elegans	O
DROME\|FlyBase=FBgn0010300\|UniProtKB=Q8MQJ9	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029444\|UniProtKB=A0A453YZF6	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_299638\|UniProtKB=E9FRJ8	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW011089\|UniProtKB=B7Q429	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG112963\|UniProtKB=T1EFN6	helobdella robusta	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_304797\|UniProtKB=E9FUX5	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020206\|UniProtKB=B7Q0E4	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW006426\|UniProtKB=B7PPF0	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG171205\|UniProtKB=T1F3X8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG166266\|UniProtKB=T1EXY6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG181506\|UniProtKB=T1FH26	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG82746\|UniProtKB=T1G4W0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG170901\|UniProtKB=T1F3K6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG166256\|UniProtKB=T1EXY4	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG171321\|UniProtKB=T1F440	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG172965\|UniProtKB=T1F681	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG171300\|UniProtKB=T1F421	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG110232\|UniProtKB=T1EF07	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g245515\|UniProtKB=A7SIN0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g119814\|UniProtKB=A7SIM9	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g197055\|UniProtKB=A7RH37	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g160201\|UniProtKB=A7RLP9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g199481\|UniProtKB=A7RMX0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g88772\|UniProtKB=A7RP84	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g199475\|UniProtKB=A7RMW4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g215519\|UniProtKB=A7SPQ3	Nematostella vectensis	O
ENTH1\|EnsemblGenome=CL6EHI_198840\|UniProtKB=C4LWT0	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_023460\|UniProtKB=C4LUQ5	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_053120\|UniProtKB=C4M3D0	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_086360\|UniProtKB=C4M8Y4	Entamoeba histolytica	O
DICPU\|EnsemblGenome=DICPUDRAFT_153743\|UniProtKB=F0ZPN2	Dictyostelium purpureum	O