PANTHER Gene Information

Gene Symbol(s):

HOXA5

Organism:

Canis lupus familiaris

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Gene Name:

Homeobox A5

Gene ID:

ENSCAFG00845011359.1

Protein ID:

A0A8I3N8Z2

Persistent Id:

PTN000674702

Alternate Ids:

545522814(GI)	ENSCAFT00845020126(Ensembl_TRS)
482370(GeneID)	XM_005628657(refSeq)
ENSCAFG00845011359(Ensembl)	ENSCAFP00845015776(Ensembl_PRO)
A0A8I3N8Z2_CANLF(UniProtKB-ID)	A0A8I3N8Z2(Synonym)
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PANTHER Classification

PANTHER Family:	HOMEOBOX PROTEIN HOX (PTHR45659)
PANTHER Subfamily:	HOMEOBOX PROTEIN HOX-A5 (PTHR45659:SF10)
PANTHER GO-slim Molecular Function:	DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process:	anterior/posterior pattern specification regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	homeodomain transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	multicellular organism growth, lung-associated mesenchyme development, negative regulation of angiogenesis, epithelial tube branching involved in lung morphogenesis, lung goblet cell differentiation, anterior/posterior pattern specification, negative regulation of erythrocyte differentiation, positive regulation of transcription by RNA polymerase II, cell-cell signaling involved in mammary gland development, mammary gland epithelial cell differentiation, lung alveolus development, mammary gland alveolus development, regulation of mammary gland epithelial cell proliferation, cell migration, intestinal epithelial cell maturation, positive regulation of myeloid cell differentiation, mesenchymal-epithelial cell signaling, embryonic skeletal system morphogenesis, bronchiole development, regulation of transcription by RNA polymerase II, trachea cartilage morphogenesis, respiratory system process, thyroid gland development, positive regulation of gene expression, positive regulation of apoptotic process
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=5106\|UniProtKB=P20719	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000019015.3\|UniProtKB=H2QUB6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000002217.3\|UniProtKB=G3QIH3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000061471.1\|UniProtKB=A0A5F8A1H7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=96177\|UniProtKB=P09021	Mus musculus	LDO
RAT\|RGD=620609\|UniProtKB=P52949	Rattus norvegicus	LDO
BOVIN\|Gene=HOXA5\|UniProtKB=Q2HJ67	Bos taurus	LDO
BOVIN\|Ensembl=ENSBTAG00000012211.5\|UniProtKB=A0A452DJA1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000016703.4\|UniProtKB=F6Q7H3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000000461.4\|UniProtKB=F7DK44	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000045684.2\|UniProtKB=A0A337SUM0	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000000483.5\|UniProtKB=F6UA74	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000009167.4\|UniProtKB=F7EJA8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010001813\|UniProtKB=Q6B3N0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010364.4\|UniProtKB=H9GGC2	Anolis carolinensis	LDO
XENLA\|Gene=hoxa5.S\|UniProtKB=A0A1L8FR89	Xenopus laevis	O
XENLA\|Gene=hoxa5.L\|UniProtKB=A0A1L8FW27	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-486061\|UniProtKB=F7D5Q3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007942.2\|UniProtKB=Q3V607	Oryzias latipes	LDO
ORYLA\|Ensembl=ENSORLG00000012387.2\|UniProtKB=H2MAF2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000017036.2\|UniProtKB=H2MRD8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000023188.1\|UniProtKB=H2LJY5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000026145.1\|UniProtKB=A0A3B3HRL3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-000823-9\|UniProtKB=Q9YGT6	Danio rerio	LDO
DANRE\|ZFIN=ZDB-GENE-980526-533\|UniProtKB=P09074	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-000822-1\|UniProtKB=Q9PWM5	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000011824.1\|UniProtKB=W5N1M9	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000011819.1\|UniProtKB=W5N1M1	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118403105\|UniProtKB=A0A9J7HFR5	Branchiostoma floridae	O
BRAFL\|Gene=AmphiHox8\|UniProtKB=A9GC97	Branchiostoma floridae	O
BRAFL\|Gene=AmphiHox7\|UniProtKB=A9GCA1	Branchiostoma floridae	O
STRPU\|EnsemblGenome=GeneID_373356\|UniProtKB=P13545	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC588358\|UniProtKB=A0A7M7RDT6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC574804\|UniProtKB=A0A7M7LLG5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446743\|UniProtKB=A0A7M7LWN1	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00001174\|UniProtKB=P17486	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG00023\|UniProtKB=A8WM58	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00023539\|UniProtKB=Q9GZ03	Caenorhabditis briggsae	O
DROME\|FlyBase=FBgn0003944\|UniProtKB=P83949	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP004661\|UniProtKB=Q7PGA9	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC000903\|UniProtKB=Q8T939	Tribolium castaneum	O
DROME\|FlyBase=FBgn0000014\|UniProtKB=P29555	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP004662\|UniProtKB=O76762	Anopheles gambiae	O
DROME\|FlyBase=FBgn0001077\|UniProtKB=P02835	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0260642\|UniProtKB=P02833	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP013157\|UniProtKB=F5HK01	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP004660\|UniProtKB=O76761	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC000916\|UniProtKB=D6W935	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC000894\|UniProtKB=D6W912	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC000912\|UniProtKB=Q95UR2	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347212\|UniProtKB=E9G1J0	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347209\|UniProtKB=E9G1J3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347228\|UniProtKB=E9G1J7	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347208\|UniProtKB=E9G1J1	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG76830\|UniProtKB=T1G2P8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG78362\|UniProtKB=T1G3B0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG116524\|UniProtKB=T1EGF6	helobdella robusta	O
HELRO\|Gene=LOX2\|UniProtKB=Q01622	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG183449\|UniProtKB=T1FJP2	helobdella robusta	O