PANTHER Gene Information

Gene Symbol(s):

Ubx

Organism:

Drosophila melanogaster

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Gene Name:

Homeotic protein ultrabithorax

Gene ID:

FBgn0003944

Protein ID:

P83949

Persistent Id:

PTN000674948

Alternate Ids:

Q9VER4(AltAccession)	23171495(GI)
FBgn0003944(Ensembl)	UBX_DROME(UniProtKB-ID)
K01959(EMBL)	AAA84412(EMBL-CDS)
Ubx(Symbol)	UBX(Synonym)
42034(GeneID)	FBgn0003944(FlyBase)
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PANTHER Classification

PANTHER Family:	HOMEOBOX PROTEIN HOX (PTHR45659)
PANTHER Subfamily:	HOMEOTIC PROTEIN ULTRABITHORAX (PTHR45659:SF21)
PANTHER GO-slim Molecular Function:	DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process:	negative regulation of transcription by RNA polymerase II anterior/posterior pattern specification
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	homeodomain transcription factor

Pathway Categories:

Wnt signaling pathway

Wnt Target Genes

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	transcription coregulator binding, DNA binding, protein domain specific binding, protein binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, cis-regulatory region sequence-specific DNA binding, sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	imaginal disc-derived leg morphogenesis, regulation of cell fate specification, specification of segmental identity, thorax, midgut development, specification of animal organ identity, dorsal vessel aortic cell fate commitment, haltere development, anterior/posterior pattern specification, positive regulation of muscle organ development, regulation of DNA-templated transcription, muscle cell fate specification, somatic muscle development, open tracheal system development, mesodermal cell fate specification, anterior Malpighian tubule development, negative regulation of transcription by RNA polymerase II, heart development, regulation of imaginal disc growth, negative regulation of DNA-templated transcription, positive regulation of DNA-templated transcription, endoderm formation, cell fate determination
GO CC Complete:	nucleus, transcription regulator complex, polytene chromosome band, transcription repressor complex, protein-DNA complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=5116\|UniProtKB=P09067	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000009355.6\|UniProtKB=H2QDC1	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000023582.2\|UniProtKB=G3S8F3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000051420.1\|UniProtKB=A0A5F7ZKH5	Macaca mulatta	O
MOUSE\|MGI=MGI=96186\|UniProtKB=P09079	Mus musculus	O
RAT\|RGD=1562292\|UniProtKB=D3ZMA1	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000045835.2\|UniProtKB=G3MYX4	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000017540.5\|UniProtKB=F1RWG0	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000012439.3\|UniProtKB=F6SJ66	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000039068.3\|UniProtKB=A0A2I2V4A0	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845009832.1\|UniProtKB=A0A8I3NPD1	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000012338.2\|UniProtKB=F7E2D8	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000051056.1\|UniProtKB=A0A6I8P890	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010023394.1\|UniProtKB=Q5I188	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000042998.1\|UniProtKB=A0A803TV01	Anolis carolinensis	O
XENLA\|Gene=hoxb5.S\|UniProtKB=A0A1L8EL08	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-1005991\|UniProtKB=F6Q943	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000017041.2\|UniProtKB=Q3V618	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000022001.1\|UniProtKB=Q3V611	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-000823-6\|UniProtKB=P09013	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-980526-70\|UniProtKB=P09014	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000013440.1\|UniProtKB=W5N7G2	lepisosteus oculatus	O
HUMAN\|HGNC=5118\|UniProtKB=P09629	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000009357.6\|UniProtKB=H2QDC3	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002637\|UniProtKB=A1YFA5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000055324.1\|UniProtKB=A0A5F7ZWP8	Macaca mulatta	O
MOUSE\|MGI=MGI=96188\|UniProtKB=P09024	Mus musculus	O
RAT\|RGD=1559918\|UniProtKB=P18864	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000005546.4\|UniProtKB=F1N1K1	Bos taurus	O
BOVIN\|Gene=HOXB7\|UniProtKB=Q9TT89	Bos taurus	O
PIG\|Ensembl=ENSSSCG00005025942.1\|UniProtKB=F1RWG2	Sus scrofa	O
FELCA\|Ensembl=ENSFCAG00000002118.4\|UniProtKB=M3VXX8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845009899.1\|UniProtKB=A0A8I3NDH2	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000044053.1\|UniProtKB=A0A5F8H5Q3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000051269.1\|UniProtKB=A0A6I8NBH3	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010023381.1\|UniProtKB=A0A1D5PE06	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000041279.1\|UniProtKB=A0A803TRP5	Anolis carolinensis	O
DANRE\|ZFIN=ZDB-GENE-000329-2\|UniProtKB=Q8AWY9	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000013448.1\|UniProtKB=W5N7H0	lepisosteus oculatus	O
HUMAN\|HGNC=5117\|UniProtKB=P17509	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000009356.4\|UniProtKB=H2QDC2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002634.3\|UniProtKB=G3QJJ5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000062283.1\|UniProtKB=F7HN78	Macaca mulatta	O
MOUSE\|MGI=MGI=96187\|UniProtKB=P09023	Mus musculus	O
RAT\|RGD=1562142\|UniProtKB=D3ZLU8	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000050006.1\|UniProtKB=A0A3Q1NG70	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000017539.5\|UniProtKB=F1RWG1	Sus scrofa	O
FELCA\|Ensembl=ENSFCAG00000034768.3\|UniProtKB=A0A2I2V0Z8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845009871.1\|UniProtKB=A0A8I3N2L2	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000012334.4\|UniProtKB=F7E2G1	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000050952.1\|UniProtKB=A0A6I8NKU1	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010023383.1\|UniProtKB=A0A1D5PZQ6	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000034900.1\|UniProtKB=A0A803TCM1	Anolis carolinensis	O
XENLA\|Gene=hoxb6.L\|UniProtKB=A0A1L8ES26	Xenopus laevis	O
XENLA\|Gene=hoxb6.S\|UniProtKB=Q05AW4	Xenopus laevis	O
DANRE\|ZFIN=ZDB-GENE-000823-7\|UniProtKB=Q9YGT4	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-990415-106\|UniProtKB=P15861	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000013443.1\|UniProtKB=W5N7G7	lepisosteus oculatus	O
HUMAN\|HGNC=5128\|UniProtKB=P09630	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000022997.4\|UniProtKB=H2Q635	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000001628.3\|UniProtKB=G3QGY7	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000046055.2\|UniProtKB=F7HTX2	Macaca mulatta	O
MOUSE\|MGI=MGI=96197\|UniProtKB=P10629	Mus musculus	O
RAT\|RGD=620626\|UniProtKB=A0A8I6GM16	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000009238.5\|UniProtKB=F1MEU5	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000030585.4\|UniProtKB=A0A4X1WBT9	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000003682.4\|UniProtKB=F6Y566	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000032656.3\|UniProtKB=A0A2I2UX54	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845018203.1\|UniProtKB=A0A8I3NVN6	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000043586.1\|UniProtKB=A0A5F8HGN7	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000046423.1\|UniProtKB=A0A6I8NRL5	Ornithorhynchus anatinus	O
ANOCA\|Ensembl=ENSACAG00000010917.3\|UniProtKB=G1KKM7	Anolis carolinensis	O
XENLA\|Gene=hoxc6.S\|UniProtKB=A0A8J0UI33	Xenopus laevis	O
XENLA\|Gene=hoxc6\|UniProtKB=P02832	Xenopus laevis	O
XENLA\|Gene=hoxc6.L\|UniProtKB=A0A1L8HIF0	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-478131\|UniProtKB=A0A8J0QYS1	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000025750.1\|UniProtKB=H2LV23	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-990415-113\|UniProtKB=P15862	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000006348.1\|UniProtKB=W5MH05	lepisosteus oculatus	O
HUMAN\|HGNC=5107\|UniProtKB=P31267	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000039535.2\|UniProtKB=H2REI2	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000049275.1\|UniProtKB=A0A2I3RPG5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002218.3\|UniProtKB=G3QIH5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000061724.1\|UniProtKB=A0A5F8A595	Macaca mulatta	O
MOUSE\|MGI=MGI=96178\|UniProtKB=P09092	Mus musculus	O
RAT\|RGD=1590236\|UniProtKB=G3V6T4	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000024341.5\|UniProtKB=E1B7T2	Bos taurus	O
HORSE\|Ensembl=ENSECAG00000000575.3\|UniProtKB=F7CXU1	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000034134.3\|UniProtKB=A0A2I2UFH4	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845011371.1\|UniProtKB=A0A8I3RWG5	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000000472.3\|UniProtKB=F6UAS0	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000009168.4\|UniProtKB=F7EBY1	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010001819\|UniProtKB=Q5YLH5	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000010349.3\|UniProtKB=A0A803TBN1	Anolis carolinensis	O
XENLA\|Gene=LOC108719928\|UniProtKB=A0A1L8FR85	Xenopus laevis	O
XENLA\|Gene=LOC108718898\|UniProtKB=A0A1L8FW71	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-481964\|UniProtKB=A0A6I8QY84	Xenopus tropicalis	O
HUMAN\|HGNC=5108\|UniProtKB=P31268	Homo sapiens	O
PANTR\|Gene=HOXA7\|UniProtKB=A2T7F3	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000047796.1\|UniProtKB=H2QUB7	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002220.3\|UniProtKB=G3QIH6	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000013458.4\|UniProtKB=F6YGS3	Macaca mulatta	O
MOUSE\|MGI=MGI=96179\|UniProtKB=P02830	Mus musculus	O
BOVIN\|Ensembl=ENSBTAG00000001455.6\|UniProtKB=E1B8D8	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000016701.5\|UniProtKB=I3LKE3	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000054772.1\|UniProtKB=A0A9L0TEL4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000022150.4\|UniProtKB=M3WZ10	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845011385.1\|UniProtKB=A0A8I3NDF7	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000038697.1\|UniProtKB=A0A5F8GL29	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000046422.1\|UniProtKB=A0A6I8P3C7	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010001826\|UniProtKB=Q90VZ9	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000010322.3\|UniProtKB=H9GGA6	Anolis carolinensis	O
XENLA\|Gene=hoxa7\|UniProtKB=P09071	Xenopus laevis	O
XENLA\|Gene=hoxa7.S\|UniProtKB=A0A1L8FRB9	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-483655\|UniProtKB=F7D5P6	Xenopus tropicalis	O
HUMAN\|HGNC=5127\|UniProtKB=Q00444	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000052329.1\|UniProtKB=K7CBJ4	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000001629.3\|UniProtKB=G3QGY9	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000062271.1\|UniProtKB=G7N762	Macaca mulatta	O
MOUSE\|MGI=MGI=96196\|UniProtKB=P32043	Mus musculus	O
RAT\|RGD=1307584\|UniProtKB=D3ZP88	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000009634.5\|UniProtKB=E1BHR6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00005014225.1\|UniProtKB=A0A4X1WAM0	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000004151.3\|UniProtKB=F6WR44	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000032832.3\|UniProtKB=A0A2I2UXE6	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845018144.1\|UniProtKB=A0A8I3PAE7	Canis lupus familiaris	O
ANOCA\|Ensembl=ENSACAG00000010927.4\|UniProtKB=G1KKN3	Anolis carolinensis	O
HUMAN\|HGNC=5106\|UniProtKB=P20719	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000019015.3\|UniProtKB=H2QUB6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002217.3\|UniProtKB=G3QIH3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000061471.1\|UniProtKB=A0A5F8A1H7	Macaca mulatta	O
MOUSE\|MGI=MGI=96177\|UniProtKB=P09021	Mus musculus	O
RAT\|RGD=620609\|UniProtKB=P52949	Rattus norvegicus	O
BOVIN\|Gene=HOXA5\|UniProtKB=Q2HJ67	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000012211.5\|UniProtKB=A0A452DJA1	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000016703.4\|UniProtKB=F6Q7H3	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000000461.4\|UniProtKB=F7DK44	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000045684.2\|UniProtKB=A0A337SUM0	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845011359.1\|UniProtKB=A0A8I3N8Z2	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000000483.5\|UniProtKB=F6UA74	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000009167.4\|UniProtKB=F7EJA8	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010001813\|UniProtKB=Q6B3N0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000010364.4\|UniProtKB=H9GGC2	Anolis carolinensis	O
XENLA\|Gene=hoxa5.S\|UniProtKB=A0A1L8FR89	Xenopus laevis	O
XENLA\|Gene=hoxa5.L\|UniProtKB=A0A1L8FW27	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-486061\|UniProtKB=F7D5Q3	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000007942.2\|UniProtKB=Q3V607	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000012387.2\|UniProtKB=H2MAF2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000017036.2\|UniProtKB=H2MRD8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000023188.1\|UniProtKB=H2LJY5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000026145.1\|UniProtKB=A0A3B3HRL3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-000823-9\|UniProtKB=Q9YGT6	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-980526-533\|UniProtKB=P09074	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-000822-1\|UniProtKB=Q9PWM5	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000011824.1\|UniProtKB=W5N1M9	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000011819.1\|UniProtKB=W5N1M1	lepisosteus oculatus	O
BRAFL\|Gene=LOC118403105\|UniProtKB=A0A9J7HFR5	Branchiostoma floridae	O
BRAFL\|Gene=AmphiHox8\|UniProtKB=A9GC97	Branchiostoma floridae	O
BRAFL\|Gene=AmphiHox7\|UniProtKB=A9GCA1	Branchiostoma floridae	O
STRPU\|EnsemblGenome=GeneID_373356\|UniProtKB=P13545	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC588358\|UniProtKB=A0A7M7RDT6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC574804\|UniProtKB=A0A7M7LLG5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446743\|UniProtKB=A0A7M7LWN1	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00001174\|UniProtKB=P17486	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG00023\|UniProtKB=A8WM58	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00023539\|UniProtKB=Q9GZ03	Caenorhabditis briggsae	O
ANOGA\|EnsemblGenome=AGAP004661\|UniProtKB=Q7PGA9	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC000903\|UniProtKB=Q8T939	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_347212\|UniProtKB=E9G1J0	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347209\|UniProtKB=E9G1J3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347228\|UniProtKB=E9G1J7	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347208\|UniProtKB=E9G1J1	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG76830\|UniProtKB=T1G2P8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG78362\|UniProtKB=T1G3B0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG116524\|UniProtKB=T1EGF6	helobdella robusta	O
HELRO\|Gene=LOX2\|UniProtKB=Q01622	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG183449\|UniProtKB=T1FJP2	helobdella robusta	O