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Gene Symbol(s):
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FGF4
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| Organism: |
Canis lupus familiaris |
| View Gene in Tree |
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| Gene Name: |
Fibroblast growth factor
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| Gene ID: |
ENSCAFG00845015112.1
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| Protein ID: |
J9P3I7
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| Persistent Id: |
PTN001352922 |
| Alternate Ids: |
| ENSCAFP00845021246(Ensembl_PRO) |
J9P3I7(Synonym) |
| XP_540801(refSeq) |
483680(GeneID) |
| 73983565(GI) |
J9P3I7_CANLF(UniProtKB-ID) |
| LR130457(EMBL) |
ENSCAFG00845015112(Ensembl) |
| ENSCAFT00845026999(Ensembl_TRS) |
VDK11037(EMBL-CDS) |
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Show All
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| GO MF Complete: |
growth factor activity, fibroblast growth factor receptor binding
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| GO BP Complete: |
cranial suture morphogenesis, apoptotic process involved in morphogenesis, chondroblast differentiation, positive regulation of cell population proliferation, fibroblast growth factor receptor signaling pathway, epithelial cell apoptotic process, neurogenesis, odontogenesis of dentin-containing tooth, positive regulation of MAPK cascade, positive regulation of transcription by RNA polymerase II, cartilage condensation, positive regulation of cell division, cellular response to leukemia inhibitory factor, positive regulation of gene expression, negative regulation of apoptotic process, positive regulation of stem cell proliferation, positive regulation of ERK1 and ERK2 cascade, stem cell proliferation, somatic stem cell population maintenance, regulation of endothelial cell chemotaxis to fibroblast growth factor, regulation of cell migration, mesenchymal cell proliferation, embryonic hindlimb morphogenesis
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| GO CC Complete: |
extracellular space, cytoplasm
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| Reactome Pathways: |
Signaling by FGFR3, PI3K Cascade, Phospholipase C-mediated cascade; FGFR4, FGFRL1 modulation of FGFR1 signaling, Signaling by FGFR4, Phospholipase C-mediated cascade; FGFR3, FRS-mediated FGFR2 signaling, IRS-related events triggered by IGF1R, Insulin receptor signalling cascade, Signaling by Insulin receptor, IGF1R signaling cascade, Phospholipase C-mediated cascade; FGFR2, FGFR1c ligand binding and activation, FGFR3c ligand binding and activation, FGFR2c ligand binding and activation, FRS-mediated FGFR3 signaling, MAPK1/MAPK3 signaling, SHC-mediated cascade:FGFR3, IRS-mediated signalling, Downstream signaling of activated FGFR3, PI-3K cascade:FGFR2, Downstream signaling of activated FGFR2, Negative regulation of FGFR3 signaling, SHC-mediated cascade:FGFR2, Negative regulation of FGFR4 signaling, FRS-mediated FGFR1 signaling, Signal Transduction, PIP3 activates AKT signaling, Intracellular signaling by second messengers, Signaling by FGFR2, Phospholipase C-mediated cascade: FGFR1, Signaling by FGFR1, Downstream signaling of activated FGFR1, PI-3K cascade:FGFR4, SHC-mediated cascade:FGFR1, PI-3K cascade:FGFR1, RAF/MAP kinase cascade, Signaling by FGFR, Signaling by Receptor Tyrosine Kinases, Negative regulation of FGFR2 signaling, Negative regulation of FGFR1 signaling, FGFR3 ligand binding and activation, FRS-mediated FGFR4 signaling, PI-3K cascade:FGFR3, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, FGFR4 ligand binding and activation, FGFR2 ligand binding and activation, FGFR1 ligand binding and activation, Downstream signaling of activated FGFR4, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), Negative regulation of the PI3K/AKT network, SHC-mediated cascade:FGFR4, MAPK family signaling cascades
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