PANTHER Gene Information   
Gene Symbol(s): FGF4
Organism: Sus scrofa
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Gene Name: Fibroblast growth factor
Gene ID: ENSSSCG00000012870.4
Protein ID: F1RY80
Persistent Id: PTN001352920
Alternate Ids:
F1RY80_PIG(UniProtKB-ID) AB745732(EMBL)
BAM77405(EMBL-CDS) F1RY80(Synonym)
XP_003122466(refSeq) 440647174(GI)
ENSSSCP00000013681(Ensembl_PRO) 100518595(GeneID)
ENSSSCG00000012870(Ensembl) ENSSSCT00000014067(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: FIBROBLAST GROWTH FACTOR (PTHR11486)
PANTHER Subfamily: FIBROBLAST GROWTH FACTOR 4 (PTHR11486:SF31)  
PANTHER GO-slim Molecular Function: growth factor activity
fibroblast growth factor receptor binding
PANTHER GO-slim Biological Process: regulation of cell migration
fibroblast growth factor receptor signaling pathway
positive regulation of protein phosphorylation
cell differentiation
positive regulation of MAPK cascade
positive regulation of gene expression
positive regulation of cell population proliferation
animal organ morphogenesis
PANTHER GO-slim Cellular Component: extracellular space
cytoplasm
PANTHER protein class: growth factor
Pathway Categories: FGF signaling pathway
   fibroblast growth factor
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: growth factor activity, fibroblast growth factor receptor binding
GO BP Complete: cranial suture morphogenesis, apoptotic process involved in morphogenesis, chondroblast differentiation, positive regulation of cell population proliferation, fibroblast growth factor receptor signaling pathway, epithelial cell apoptotic process, neurogenesis, odontogenesis of dentin-containing tooth, positive regulation of MAPK cascade, positive regulation of transcription by RNA polymerase II, cartilage condensation, positive regulation of cell division, cellular response to leukemia inhibitory factor, positive regulation of gene expression, negative regulation of apoptotic process, positive regulation of stem cell proliferation, positive regulation of ERK1 and ERK2 cascade, stem cell proliferation, somatic stem cell population maintenance, regulation of endothelial cell chemotaxis to fibroblast growth factor, regulation of cell migration, mesenchymal cell proliferation, embryonic hindlimb morphogenesis
GO CC Complete: extracellular space, cytoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: SHC-mediated cascade:FGFR4, Signal Transduction, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), FRS-mediated FGFR4 signaling, Signaling by FGFR, Negative regulation of FGFR4 signaling, Signaling by FGFR1, Phospholipase C-mediated cascade: FGFR1, Downstream signaling of activated FGFR4, FRS-mediated FGFR1 signaling, FGFR1c ligand binding and activation, Intracellular signaling by second messengers, MAPK1/MAPK3 signaling, PI3K Cascade, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, IRS-related events triggered by IGF1R, Signaling by FGFR4, SHC-mediated cascade:FGFR1, FGFR4 ligand binding and activation, Downstream signaling of activated FGFR1, PI-3K cascade:FGFR4, PI-3K cascade:FGFR1, Phospholipase C-mediated cascade; FGFR4, IRS-mediated signalling, Negative regulation of FGFR1 signaling, Negative regulation of the PI3K/AKT network, MAPK family signaling cascades, Signaling by Insulin receptor, FGFRL1 modulation of FGFR1 signaling, FGFR1 ligand binding and activation, Signaling by Receptor Tyrosine Kinases, Insulin receptor signalling cascade, IGF1R signaling cascade, RAF/MAP kinase cascade, PIP3 activates AKT signaling

Orthologs