PANTHER Gene Information   
Gene Symbol(s): GATA2
Organism: Canis lupus familiaris
View Gene in Tree
Tree
Tree
Gene Name: GATA binding protein 2
Gene ID: ENSCAFG00845018934.1
Protein ID: A0A8I3S3Q3
Persistent Id: PTN000007708
Alternate Ids:
A0A8I3S3Q3_CANLF(UniProtKB-ID) ENSCAFT00845033436(Ensembl_TRS)
ENSCAFG00845018934(Ensembl) A0A8I3S3Q3(Synonym)
ENSCAFP00845026175(Ensembl_PRO)
Show All

PANTHER Classification
PANTHER Family: TRANSCRIPTION FACTOR GATA FAMILY MEMBER (PTHR10071)
PANTHER Subfamily: ENDOTHELIAL TRANSCRIPTION FACTOR GATA-2 (PTHR10071:SF149)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process: positive regulation of multicellular organismal process
positive regulation of developmental process
regulation of angiogenesis
negative regulation of transcription by RNA polymerase II
cell fate commitment
positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class: DNA-binding transcription factor
Pathway Categories: Gonadotropin-releasing hormone receptor pathway
   GATA2/4
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: zinc ion binding, RNA polymerase II-specific DNA-binding transcription factor binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, C2H2 zinc finger domain binding, DNA-binding transcription activator activity, RNA polymerase II-specific, chromatin binding, DNA-binding transcription factor activity, RNA polymerase II-specific, transcription coactivator binding
GO BP Complete: negative regulation of brown fat cell differentiation, cell differentiation in hindbrain, thyroid-stimulating hormone-secreting cell differentiation, transcription by RNA polymerase II, neuron maturation, positive regulation of miRNA transcription, ventral spinal cord interneuron differentiation, central nervous system neuron development, positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis, negative regulation of Notch signaling pathway, positive regulation of transcription by RNA polymerase II, positive regulation of cell migration involved in sprouting angiogenesis, positive regulation of erythrocyte differentiation, embryonic placenta development, hematopoietic progenitor cell differentiation, positive regulation of angiogenesis, negative regulation of transcription by RNA polymerase II, brown fat cell differentiation, neuroblast proliferation, negative regulation of neuroblast proliferation, negative regulation of macrophage differentiation, regulation of forebrain neuron differentiation, somatic stem cell population maintenance, negative regulation of endothelial cell apoptotic process, cell fate determination, eosinophil fate commitment, semicircular canal development, vascular wound healing, glandular epithelial cell maturation, commitment of neuronal cell to specific neuron type in forebrain, hematopoietic stem cell homeostasis, positive regulation of megakaryocyte differentiation, negative regulation of hematopoietic progenitor cell differentiation, definitive hemopoiesis, negative regulation of gene expression, GABAergic neuron differentiation, urogenital system development, regulation of primitive erythrocyte differentiation, homeostasis of number of cells within a tissue, positive regulation of gene expression, inner ear morphogenesis, cell fate commitment
GO CC Complete: nucleus, transcription regulator complex, cytoplasm, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Gene expression (Transcription), Generic Transcription Pathway, Transcriptional regulation by RUNX1, RUNX1 regulates transcription of genes involved in differentiation of HSCs, Hemostasis, RNA Polymerase II Transcription, Factors involved in megakaryocyte development and platelet production

Orthologs