PANTHER Gene Information   
Gene Symbol(s): NOS2
Organism: Canis lupus familiaris
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Gene Name: Nitric oxide synthase, inducible
Gene ID: NOS2
Protein ID: O62699
Persistent Id: PTN004515774
Alternate Ids:
3098283(GI) NOS2(Synonym)
NOS2_CANLF(UniProtKB-ID) NP_001300777(refSeq)
AF032909(EMBL) O97604(AltAccession)
1.14.13.39 {ECO:0000250|UniProtKB:P35228}(EC) AAC15587(EMBL-CDS)
NOS2(Symbol) 403822(GeneID)
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PANTHER Classification
PANTHER Family: NITRIC OXIDE SYNTHASE-RELATED (PTHR19384)
PANTHER Subfamily: NITRIC OXIDE SYNTHASE, INDUCIBLE (PTHR19384:SF56)  
PANTHER GO-slim Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor
carbohydrate derivative binding
flavin adenine dinucleotide binding
PANTHER GO-slim Biological Process: response to hormone
cellular nitrogen compound biosynthetic process
intracellular signaling cassette
response to lipopolysaccharide
positive regulation of lyase activity
positive regulation of cyclase activity
L-amino acid metabolic process
defense response to bacterium
inflammatory response
amino acid catabolic process
positive regulation of phosphate metabolic process
positive regulation of nucleobase-containing compound metabolic process
proteinogenic amino acid metabolic process
arginine metabolic process
negative regulation of blood pressure
positive regulation of cellular biosynthetic process
PANTHER GO-slim Cellular Component: cytosol
nucleus
plasma membrane
PANTHER protein class: oxidoreductase
Pathway Categories: PI3 kinase pathway
   NOS

GO MF Complete: calmodulin binding, NADP binding, nitric-oxide synthase activity, FMN binding, metal ion binding, flavin adenine dinucleotide binding, heme binding
GO BP Complete: peptidyl-cysteine S-nitrosylation, nitric oxide mediated signal transduction, negative regulation of blood pressure, regulation of cytokine production involved in inflammatory response, response to hormone, defense response to bacterium, arginine catabolic process, inflammatory response, positive regulation of interleukin-8 production, superoxide metabolic process, response to lipopolysaccharide, nitric oxide biosynthetic process, prostaglandin secretion, positive regulation of interleukin-6 production
GO CC Complete: nucleus, cytosol, plasma membrane
Reactome Pathways: -