PANTHER Gene Information   
Gene Symbol(s): PRKCZ
Organism: Gallus gallus
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Gene Name: Protein kinase C
Gene ID: ENSGALG00010020059.1
Protein ID: E1BQN6
Persistent Id: PTN000684136
Alternate Ids:
E1BQN6_CHICK(UniProtKB-ID) XM_417561(refSeq)
ENSGALP00010028583(Ensembl_PRO) 971429262(GI)
ENSGALG00010020059(Ensembl) 419399(GeneID)
E1BQN6(Synonym) ENSGALT00010048475(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: SERINE/THREONINE-PROTEIN KINASE (PTHR24356)
PANTHER Subfamily: PROTEIN KINASE C ZETA TYPE (PTHR24356:SF170)  
PANTHER GO-slim Molecular Function: protein serine/threonine kinase activity
PANTHER GO-slim Biological Process: peptidyl-serine phosphorylation
intracellular signal transduction
PANTHER GO-slim Cellular Component:
PANTHER protein class: non-receptor serine/threonine protein kinase
Pathway Categories: Gonadotropin-releasing hormone receptor pathway
   PKCs
Histamine H1 receptor mediated signaling pathway
   Protein kinase C
Inflammation mediated by chemokine and cytokine signaling pathway
   Protein kinase C, zeta
Inflammation mediated by chemokine and cytokine signaling pathway
   Protein kinase C
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
   Protein kinase C
Wnt signaling pathway
   Protein Kinase C
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
   Protein kinase C
Oxytocin receptor mediated signaling pathway
   Protein kinase C
FGF signaling pathway
   Protein kinase C
Thyrotropin-releasing hormone receptor signaling pathway
   Protein kinase C
Angiogenesis
   Protein kinase B
VEGF signaling pathway
   Protein kinase C
Endothelin signaling pathway
   protein kinase c
Alzheimer disease-amyloid secretase pathway
   Protein kinase C
EGF receptor signaling pathway
   PKC
5HT2 type receptor mediated signaling pathway
   Protein kinase C
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: diacylglycerol-dependent, calcium-independent serine/threonine kinase activity, ATP binding, metal ion binding, protein serine/threonine kinase activity, calcium,diacylglycerol-dependent serine/threonine kinase activity
GO BP Complete: positive regulation of T-helper 2 cell differentiation, microtubule cytoskeleton organization, negative regulation of insulin receptor signaling pathway, cellular response to insulin stimulus, positive regulation of interleukin-13 production, neuron projection extension, positive regulation of ERK1 and ERK2 cascade, establishment of cell polarity, negative regulation of protein-containing complex assembly, positive regulation of interleukin-10 production, positive regulation of interleukin-4 production, intracellular signal transduction, protein localization to plasma membrane, positive regulation of interleukin-5 production, positive regulation of T-helper 2 cell cytokine production
GO CC Complete: nuclear envelope, bicellular tight junction, microtubule organizing center, cytosol, nuclear matrix, vesicle, apical cortex, myelin sheath abaxonal region, axon hillock, apical plasma membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Signaling by VEGF, VEGFA-VEGFR2 Pathway, Signaling by Rho GTPases, Signaling by TGFB family members, Signaling by TGF-beta Receptor Complex, Signaling by Receptor Tyrosine Kinases, TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition), Signaling by Nuclear Receptors, Signal Transduction, Estrogen-stimulated signaling through PRKCZ, VEGFR2 mediated cell proliferation, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, ESR-mediated signaling, Extra-nuclear estrogen signaling, RHO GTPases Activate NADPH Oxidases, RHO GTPase Effectors

Orthologs