PANTHER Gene Information

Gene Symbol(s):

tek

Organism:

Danio rerio

View Gene in Tree


Tree	Reduced Tree

Gene Name:

receptor protein-tyrosine kinase

Gene ID:

tek

Protein ID:

A0A8M3ARU2

Persistent Id:

PTN009099240

Alternate Ids:

A0A8M3ARU2(Synonym)	A0A8M3ARU2_DANRE(UniProtKB-ID)
XM_009301113(refSeq)	688552950(GI)
30747(GeneID)
Show All

PANTHER Classification

PANTHER Family:	TYROSINE-PROTEIN KINASE RECEPTOR (PTHR24416)
PANTHER Subfamily:	ANGIOPOIETIN-1 RECEPTOR (PTHR24416:SF125)
PANTHER GO-slim Molecular Function:	transmembrane receptor protein tyrosine kinase activity
PANTHER GO-slim Biological Process:	angiogenesis regulation of angiogenesis endothelial cell proliferation positive regulation of cell migration positive regulation of multicellular organismal process positive regulation of kinase activity positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction transmembrane receptor protein tyrosine kinase signaling pathway positive regulation of developmental process positive regulation of MAPK cascade
PANTHER GO-slim Cellular Component:	plasma membrane receptor complex
PANTHER protein class:	transmembrane signal receptor

Pathway Categories:

Angiogenesis

Tie-2

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	transmembrane receptor protein tyrosine kinase activity
GO BP Complete:	angiogenesis, multicellular organism development, endothelial cell proliferation, cell surface receptor protein tyrosine kinase signaling pathway, positive regulation of MAPK cascade, positive regulation of endothelial cell migration, positive regulation of angiogenesis, positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO CC Complete:	receptor complex, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11724\|UniProtKB=Q02763	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020835.6\|UniProtKB=A0A2I3RZH3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015924.3\|UniProtKB=G3RIN5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000006080.4\|UniProtKB=F6VW12	Macaca mulatta	LDO
MOUSE\|MGI=MGI=98664\|UniProtKB=Q02858	Mus musculus	LDO
RAT\|RGD=620980\|UniProtKB=D3ZCD0	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000020148\|UniProtKB=Q06807	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000005122.6\|UniProtKB=K7GQ34	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000016566.4\|UniProtKB=A0A9L0T8J6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000002830.6\|UniProtKB=M3VZ78	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845018055.1\|UniProtKB=A0A8I3S0B4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000004269.4\|UniProtKB=F6TEV1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000013231.4\|UniProtKB=F6UTL2	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010006538.1\|UniProtKB=A0A3Q2UKD3	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000017459.4\|UniProtKB=G1KU09	Anolis carolinensis	LDO
XENLA\|Gene=tek.S\|UniProtKB=A0A1L8HP14	Xenopus laevis	O
XENLA\|Gene=tek.L\|UniProtKB=A0A8J0UZW6	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-483684\|UniProtKB=A0A6I8T2P4	Xenopus tropicalis	LDO
LEPOC\|Ensembl=ENSLOCG00000003173.1\|UniProtKB=W5M5U9	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118432243\|UniProtKB=A0A9J7NDK0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431533\|UniProtKB=A0A9J7MCD0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118410884\|UniProtKB=A0A9J7MIL3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431526\|UniProtKB=A0A9J7NCD2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118416664\|UniProtKB=A0A9J7MSZ6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431263\|UniProtKB=A0A9J7NCM0	Branchiostoma floridae	O
STRPU\|EnsemblGenome=GeneID_592402\|UniProtKB=A0A7M7PIL3	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00020966\|UniProtKB=Q23136	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG05171\|UniProtKB=A8WZA7	Caenorhabditis briggsae	O
DROME\|FlyBase=FBgn0011829\|UniProtKB=Q7KT06	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008899\|UniProtKB=A0A1S4H0B3	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC012783\|UniProtKB=D6X0D7	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_40778\|UniProtKB=E9FTN9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW003506\|UniProtKB=B7PIC9	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG133652\|UniProtKB=T1EI21	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g134557\|UniProtKB=A7SVX1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g210816\|UniProtKB=A7SE14	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g150265\|UniProtKB=A7T8I7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g1620\|UniProtKB=A7SZN9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g117565\|UniProtKB=A7SGK0	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g120496\|UniProtKB=A7SJE2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g41034\|UniProtKB=A7SQ51	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g1840\|UniProtKB=A7T537	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_38493\|UniProtKB=A9V865	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_34608\|UniProtKB=A9VCU7	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_27123\|UniProtKB=A9V4D1	Monosiga brevicollis	O