PANTHER Gene Information   
Gene Symbol(s): cb945
Organism: Danio rerio
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Gene Name: non-specific serine_threonine protein kinase
Gene ID: ZDB-GENE-031007-5
Protein ID: Q8UUX0
Persistent Id: PTN000682412
Alternate Ids:
Q8UUX0_DANRE(UniProtKB-ID) ZDB-GENE-031007-5(ZFIN)
182889760(GI) NM_198146(refSeq)
AAL16380(EMBL-CDS) ENSDARG00000011219(Ensembl)
Q8UUX0(Synonym) CT573179(EMBL)
ENSDARP00000023119(Ensembl_PRO) ENSDART00000026767(Ensembl_TRS)
378972(GeneID)
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PANTHER Classification
PANTHER Family: SERINE/THREONINE-PROTEIN KINASE (PTHR24356)
PANTHER Subfamily: RAC-BETA SERINE_THREONINE-PROTEIN KINASE (PTHR24356:SF176)  
PANTHER GO-slim Molecular Function: protein serine/threonine kinase activity
PANTHER GO-slim Biological Process: peptidyl-serine phosphorylation
intracellular signal transduction
PANTHER GO-slim Cellular Component:
PANTHER protein class: non-receptor serine/threonine protein kinase
Pathway Categories: PDGF signaling pathway
   Protein kinase B
Interleukin signaling pathway
   Protein kinase B
PI3 kinase pathway
   Protein kinase B
Endothelin signaling pathway
   protein kinase B
T cell activation
   protein kinase B
Hypoxia response via HIF activation
   protein kinase B
p53 pathway
   protein kinase B
FGF signaling pathway
   protein kinase B
p53 pathway feedback loops 2
   protein kinase B
Angiogenesis
   Protein Kinase B
p53 pathway by glucose deprivation
   protein kinase B
Apoptosis signaling pathway
   protein kinase B
Huntington disease
   protein kinase B
Insulin/IGF pathway-protein kinase B signaling cascade
   protein kinase B
Inflammation mediated by chemokine and cytokine signaling pathway
   protein kinase B
FAS signaling pathway
   Apoptosis signal regulating kinase 1
EGF receptor signaling pathway
   protein kinase B
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: nucleotide binding, ATP binding, protein kinase activity, protein serine/threonine kinase activity, transferase activity, kinase activity
GO BP Complete: negative regulation of apoptotic process, glucose homeostasis, positive regulation of D-glucose import, phosphorylation, protein phosphorylation, intracellular signal transduction, bone development
GO CC Complete: -
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Adaptive Immune System, Cytokine Signaling in Immune system, RNA Polymerase II Transcription, Estrogen-dependent nuclear events downstream of ESR-membrane signaling, Mitotic G1 phase and G1/S transition, Intracellular signaling by second messengers, Cellular response to chemical stress, PTEN Regulation, Deactivation of the beta-catenin transactivating complex, Negative regulation of the PI3K/AKT network, Regulation of TP53 Activity through Acetylation, Generic Transcription Pathway, Regulation of TP53 Degradation, AKT phosphorylates targets in the cytosol, Cellular responses to stress, S Phase, Signaling by GPCR, G-protein beta:gamma signalling, IRS-mediated signalling, VEGFA-VEGFR2 Pathway, VEGFR2 mediated vascular permeability, Regulation of TP53 Activity, Signaling by VEGF, TCF dependent signaling in response to WNT, Extra-nuclear estrogen signaling, Regulation of gene expression in beta cells, Activation of AKT2, Transcriptional Regulation by TP53, Costimulation by the CD28 family, Cell Cycle, Mitotic, PI3K Cascade, AKT phosphorylates targets in the nucleus, Developmental Biology, Cyclin A:Cdk2-associated events at S phase entry, AKT-mediated inactivation of FOXO1A, Regulation of TP53 Expression and Degradation, G beta:gamma signalling through PI3Kgamma, GPCR downstream signalling, Regulation of beta-cell development, Regulation of PTEN stability and activity, Signal Transduction, Cell Cycle, Immune System, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), FLT3 Signaling, PIP3 activates AKT signaling, Signaling by Nuclear Receptors, Cyclin E associated events during G1/S transition , Cellular responses to stimuli, Signaling by Receptor Tyrosine Kinases, KEAP1-NFE2L2 pathway, G1/S Transition, Signaling by Insulin receptor, Insulin receptor signalling cascade, IRS-related events triggered by IGF1R, FOXO-mediated transcription, IGF1R signaling cascade, Regulation of localization of FOXO transcription factors, Signaling by WNT, Gene expression (Transcription), ESR-mediated signaling, CD28 co-stimulation, CD28 dependent PI3K/Akt signaling

Orthologs