PANTHER Gene Information   
Gene Symbol(s): SCH9
Organism: Saccharomyces cerevisiae
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Gene Name: Serine_threonine-protein kinase SCH9
Gene ID: S000001248
Protein ID: P11792
Persistent Id: PTN000682457
Alternate Ids:
SCH9(Symbol) KOM1(Synonym)
856612(GeneID) YHR205W(Ensembl_PRO)
D3DLF4(AltAccession) SCH9_YEAST(UniProtKB-ID)
DAA06898(EMBL-CDS) NP_012075(refSeq)
YEAST:G3O-31231-MON(BioCyc) YHR205W(Ensembl)
S000001248(SGD) 2.7.11.1(EC)
BK006934(EMBL) 6321999(GI)
YHR205W_mRNA(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: SERINE/THREONINE-PROTEIN KINASE (PTHR24356)
PANTHER Subfamily: RAC SERINE_THREONINE-PROTEIN KINASE (PTHR24356:SF407)  
PANTHER GO-slim Molecular Function: protein serine/threonine kinase activity
PANTHER GO-slim Biological Process: peptidyl-serine phosphorylation
intracellular signal transduction
PANTHER GO-slim Cellular Component:
PANTHER protein class: non-receptor serine/threonine protein kinase
Pathway Categories: p53 pathway feedback loops 2
   protein kinase B
FGF signaling pathway
   protein kinase B
PI3 kinase pathway
   Protein kinase B
Angiogenesis
   Protein Kinase B
Endothelin signaling pathway
   protein kinase B
p53 pathway by glucose deprivation
   protein kinase B
VEGF signaling pathway
   protein kinase B
Apoptosis signaling pathway
   protein kinase B
Insulin/IGF pathway-protein kinase B signaling cascade
   protein kinase B
Hypoxia response via HIF activation
   protein kinase B
EGF receptor signaling pathway
   protein kinase B
Inflammation mediated by chemokine and cytokine signaling pathway
   protein kinase B
FAS signaling pathway
   Apoptosis signal regulating kinase 1
p53 pathway
   protein kinase B
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: histone H3S10 kinase activity, histone H2BS14 kinase activity, histone H2AS1 kinase activity, eukaryotic translation initiation factor 2alpha kinase activity, protein serine/threonine kinase activity, 3-phosphoinositide-dependent protein kinase activity, ribosomal protein S6 kinase activity, DNA-dependent protein kinase activity, ATP binding, histone H2AT120 kinase activity, AMP-activated protein kinase activity, histone H2AS121 kinase activity, histone H3S57 kinase activity, histone H4S1 kinase activity, histone H3T3 kinase activity, histone H2BS36 kinase activity, histone H3S28 kinase activity, histone H3T45 kinase activity, histone H2AXS139 kinase activity, Rho-dependent protein serine/threonine kinase activity, histone H3T11 kinase activity, protein serine kinase activity, histone H3T6 kinase activity
GO BP Complete: regulation of protein localization, regulation of cysteine metabolic process, regulation of cell size, regulation of sphingolipid biosynthetic process, positive regulation of transcription by RNA polymerase III, positive regulation of ribosomal protein gene transcription by RNA polymerase II, regulation of transcription by RNA polymerase II, positive regulation of transcription by RNA polymerase I, regulation of response to osmotic stress, chromatin remodeling, positive regulation of hydrogen sulfide biosynthetic process, cellular response to oxidative stress, intracellular signal transduction
GO CC Complete: nucleus, cytoplasm, fungal-type vacuole membrane, chromatin
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: VEGFR2 mediated vascular permeability, Negative regulation of the PI3K/AKT network, Signaling by Nuclear Receptors, Nuclear Events (kinase and transcription factor activation), Signaling by Receptor Tyrosine Kinases, Generic Transcription Pathway, IRS-mediated signalling, Signaling by GPCR, VEGFA-VEGFR2 Pathway, Signaling by NTRK1 (TRKA), PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, AKT phosphorylates targets in the nucleus, Costimulation by the CD28 family, Signaling by VEGF, Adaptive Immune System, RNA Polymerase II Transcription, PI3K Cascade, eNOS activation, Regulation of TP53 Degradation, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), Signaling by NTRKs, Activation of AKT2, IRS-related events triggered by IGF1R, GPCR downstream signalling, Insulin receptor signalling cascade, Metabolism of nitric oxide: NOS3 activation and regulation, Signaling by Insulin receptor, IGF1R signaling cascade, G beta:gamma signalling through PI3Kgamma, Transcriptional Regulation by TP53, Regulation of TP53 Activity, Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA, G-protein beta:gamma signalling, Extra-nuclear estrogen signaling, ESR-mediated signaling, Gene expression (Transcription), Immune System, CD28 co-stimulation, Metabolism, CTLA4 inhibitory signaling, CD28 dependent PI3K/Akt signaling, Metabolism of vitamins and cofactors, Regulation of mRNA stability by proteins that bind AU-rich elements, Intracellular signaling by second messengers, Regulation of TP53 Expression and Degradation, PIP3 activates AKT signaling, NGF-stimulated transcription, Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, Metabolism of RNA, Signal Transduction, Metabolism of cofactors

Orthologs