The mission of the PANTHER knowledgebase is to support biomedical and other research by providing
comprehensive information about the evolution of protein-coding gene families, particularly
protein phylogeny, function and genetic variation impacting that function. Learn more

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Current Release: PANTHER 19.0 | 15,683 family phylogenetic trees | 144 species | News
Whole genome function views

PANTHER Gene Information

Gene Symbol(s):

gdf8l

Organism:

Danio rerio

View Gene in Tree


Tree	Reduced Tree

Gene Name:

Growth_differentiation factor 8

Gene ID:

ZDB-GENE-050208-735

Protein ID:

Q68IN2

Persistent Id:

PTN000218830

Alternate Ids:

ZDB-GENE-050208-735(ZFIN)	445816(GeneID)
ENSDART00000063055(Ensembl_TRS)	ENSDARP00000063054(Ensembl_PRO)
BX548072(EMBL)	Q68IN2(Synonym)
ENSDARG00000042947(Ensembl)	AAI63669(EMBL-CDS)
NM_001004122(refSeq)	190337262(GI)
Q68IN2_DANRE(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	TGF-BETA FAMILY (PTHR11848)
PANTHER Subfamily:	GROWTH_DIFFERENTIATION FACTOR 8 (PTHR11848:SF150)
PANTHER GO-slim Molecular Function:	cytokine activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	growth factor

Pathway Categories:

TGF-beta signaling pathway

Transforming growth factor beta

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	growth factor activity, cytokine activity
GO BP Complete:	immune response
GO CC Complete:	extracellular space, extracellular region

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

-

Orthologs

ID	Organism	Type
PANTR\|Gene=MSTN\|UniProtKB=A1C2V0	Pan troglodytes	O
GORGO\|Gene=MSTN\|UniProtKB=A1C2V5	Gorilla gorilla gorilla	O
HUMAN\|HGNC=4223\|UniProtKB=O14793	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000012738.4\|UniProtKB=A0A2K6HHF2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000027833.2\|UniProtKB=A0A2K5TIY7	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000014307\|UniProtKB=A1C2U6	Macaca mulatta	O
MOUSE\|MGI=MGI=95691\|UniProtKB=O08689	Mus musculus	O
RAT\|RGD=3115\|UniProtKB=O35312	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000011808\|UniProtKB=O18836	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000016047\|UniProtKB=O18831	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000021373.3\|UniProtKB=F6S5D9	Equus caballus	O
HORSE\|Gene=MSTN\|UniProtKB=Q9GM97	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000029333.4\|UniProtKB=M3WPT7	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845024446\|UniProtKB=Q6UKZ8	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000011550.4\|UniProtKB=F6QWE0	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000043006.1\|UniProtKB=A0A6I8PB41	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010012852\|UniProtKB=O42220	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000004208.3\|UniProtKB=A0A803T4J9	Anolis carolinensis	O
XENLA\|Gene=mstn.2.S\|UniProtKB=A0A1L8EPU9	Xenopus laevis	O
XENLA\|Gene=LOC108701488\|UniProtKB=A0A1L8EX41	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-855713\|UniProtKB=A0A803JZQ6	Xenopus tropicalis	O
XENLA\|Gene=mstn.1.L\|UniProtKB=A0A1L8EX96	Xenopus laevis	O
XENLA\|Gene=mstn.1.S\|UniProtKB=A0A1L8EQ37	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-483324\|UniProtKB=A0A803JS15	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000015057.2\|UniProtKB=A0A3B3HAX7	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000008826.1\|UniProtKB=W5MQS7	lepisosteus oculatus	O
BRAFL\|Gene=LOC118423923\|UniProtKB=A0A9J7N2V0	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC115918786\|UniProtKB=A0A7M7T176	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0026199\|UniProtKB=Q9V4F4	Drosophila melanogaster	O
TRICA\|EnsemblGenome=TC015805\|UniProtKB=D2A418	Tribolium castaneum	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g196852\|UniProtKB=A7RGJ4	Nematostella vectensis	O