PANTHER Gene Information

Gene Symbol(s):

prkceb

Organism:

Danio rerio

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Gene Name:

Protein kinase C

Gene ID:

ZDB-GENE-081028-47

Protein ID:

B8A467

Persistent Id:

PTN001220216

Alternate Ids:

B8A467_DANRE(UniProtKB-ID)	BX248102(EMBL)
B8A467(Synonym)	XM_002664118(refSeq)
ENSDARP00000149617(Ensembl_PRO)	528497270(GI)
ENSDARG00000069928(Ensembl)	ENSDART00000193525(Ensembl_TRS)
100332055(GeneID)	ZDB-GENE-081028-47(ZFIN)
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PANTHER Classification

PANTHER Family:	SERINE/THREONINE-PROTEIN KINASE (PTHR24356)
PANTHER Subfamily:	PROTEIN KINASE C EPSILON TYPE (PTHR24356:SF159)
PANTHER GO-slim Molecular Function:	protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:	peptidyl-serine phosphorylation intracellular signal transduction
PANTHER GO-slim Cellular Component:
PANTHER protein class:	non-receptor serine/threonine protein kinase

Pathway Categories:

Gonadotropin-releasing hormone receptor pathway

PKCs

Histamine H1 receptor mediated signaling pathway

Protein kinase C

Apoptosis signaling pathway

Protein kinase C

Inflammation mediated by chemokine and cytokine signaling pathway

Protein kinase C

Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway

Protein kinase C

CCKR signaling map

PKCepsilon

Muscarinic acetylcholine receptor 1 and 3 signaling pathway

Protein kinase C

Oxytocin receptor mediated signaling pathway

Protein kinase C

Wnt signaling pathway

Protein Kinase C

Thyrotropin-releasing hormone receptor signaling pathway

Protein kinase C

FGF signaling pathway

Protein kinase C

Angiogenesis

Protein kinase B

Gonadotropin-releasing hormone receptor pathway

PKCs(3)

Gonadotropin-releasing hormone receptor pathway

PKCe/theta

Alpha adrenergic receptor signaling pathway

protein kinase C

Gonadotropin-releasing hormone receptor pathway

nPKCs

VEGF signaling pathway

Protein kinase C

Endothelin signaling pathway

protein kinase c

Alzheimer disease-amyloid secretase pathway

Protein kinase C

EGF receptor signaling pathway

PKC

5HT2 type receptor mediated signaling pathway

Protein kinase C

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	nucleotide binding, ATP binding, metal ion binding, protein kinase activity, protein serine/threonine kinase activity, transferase activity, kinase activity, diacylglycerol-dependent serine/threonine kinase activity
GO BP Complete:	podocyte development, glomerular filtration, phosphorylation, protein phosphorylation, intracellular signal transduction
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Role of phospholipids in phagocytosis, Effects of PIP2 hydrolysis, GPCR downstream signalling, Signaling by GPCR, Intracellular signaling by second messengers, Hemostasis, Signal Transduction, Fcgamma receptor (FCGR) dependent phagocytosis, Platelet activation, signaling and aggregation, G alpha (q) signalling events, DAG and IP3 signaling, Immune System, Innate Immune System

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9401\|UniProtKB=Q02156	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000011890.6\|UniProtKB=K7CBH8	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000014425.4\|UniProtKB=F7BIC2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97599\|UniProtKB=P16054	Mus musculus	LDO
RAT\|RGD=61925\|UniProtKB=P09216	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000008444.5\|UniProtKB=F1S5K7	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000005102.6\|UniProtKB=A0A2I2USU9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845027571.1\|UniProtKB=A0A8I3Q258	Canis lupus familiaris	LDO
CHICK\|Ensembl=ENSGALG00010018393.1\|UniProtKB=A0A8V0ZD48	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003872.4\|UniProtKB=A0A803SP35	Anolis carolinensis	LDO
BRAFL\|Gene=LOC118413941\|UniProtKB=A0A9J7L0A2	Branchiostoma floridae	LDO
CAEEL\|WormBase=WBGene00004032\|UniProtKB=P34885	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG23354\|UniProtKB=A8Y443	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00117214\|UniProtKB=A0A2A6CRU5	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0003093\|UniProtKB=P13678	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002748\|UniProtKB=A0A1S4GFU0	Anopheles gambiae	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_301963\|UniProtKB=E9GB27	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW004410\|UniProtKB=B7PJ72	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG64769\|UniProtKB=T1FXY8	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g245970\|UniProtKB=A7SL27	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG30067\|UniProtKB=B3S6K6	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_31267\|UniProtKB=A9USR5	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_10752\|UniProtKB=A9V750	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_21555\|UniProtKB=A9V1T6	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_34036\|UniProtKB=A9V9H6	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_39232\|UniProtKB=A9VD19	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_20766\|UniProtKB=A9UXQ2	Monosiga brevicollis	O
YEAST\|SGD=S000000201\|UniProtKB=P24583	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ACR191C\|UniProtKB=Q75BT0	Eremothecium gossypii	O
CANAL\|CGD=CAL0000201435\|UniProtKB=Q5ANK2	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F09746g\|UniProtKB=Q6C292	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_00106\|UniProtKB=C8VQM0	Emericella nidulans	O
NEUCR\|EnsemblGenome=NCU06544\|UniProtKB=P87253	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_07073\|UniProtKB=Q0UME1	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC17G8.14c\|UniProtKB=P36582	Schizosaccharomyces pombe	O
SCHPO\|PomBase=SPBC12D12.04c\|UniProtKB=P36583	Schizosaccharomyces pombe	O
CRYNJ\|EnsemblGenome=CNE01630\|UniProtKB=Q5KH12	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNC03300\|UniProtKB=Q5KKE3	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_15023\|UniProtKB=A0A0D1DRE2	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_12641\|UniProtKB=E3KRH5	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_15370\|UniProtKB=F4NTP5	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_19449\|UniProtKB=F4P170	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_125820\|UniProtKB=C4LVW8	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_097620\|UniProtKB=C4M933	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_188930\|UniProtKB=C4M2W0	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_044470\|UniProtKB=B1N2G7	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_042150\|UniProtKB=C4M4G9	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_053040\|UniProtKB=C4M3C2	Entamoeba histolytica	O
ENTH1\|Gene_ORFName=EHI_138540\|UniProtKB=A0A8U0WPI4	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0288795\|UniProtKB=Q54IF2	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_149347\|UniProtKB=F0ZDG7	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0268620\|UniProtKB=P54644	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_152431\|UniProtKB=F0ZLC3	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_38849\|UniProtKB=F0ZVB0	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_30_0800\|UniProtKB=Q4Q7M5	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.01.2290\|UniProtKB=Q383M7	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.3.2690\|UniProtKB=Q582Y1	Trypanosoma brucei	O
GIAIC\|EnsemblGenome=GL50803_11364\|UniProtKB=E2RTY0	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_195270\|UniProtKB=A2FLX7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_324020\|UniProtKB=A2F4A4	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_430560\|UniProtKB=A2E382	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_316050\|UniProtKB=A2FAW3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_447920\|UniProtKB=A2DS63	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_047250\|UniProtKB=A2FHJ2	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_267830\|UniProtKB=A2DLD2	Trichomonas vaginalis	O
SACS2\|EnsemblGenome=SSO3207\|UniProtKB=Q97U18	Sulfolobus solfataricus	O