PANTHER Gene Information

Gene Symbol(s):

Nsun2

Organism:

Drosophila melanogaster

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Gene Name:

tRNA (cytosine(34)-C(5))-methyltransferase

Gene ID:

FBgn0026079

Protein ID:

Q9W4M9

Persistent Id:

PTN000516114

Alternate Ids:

CAA21831(EMBL-CDS)	AE014298(EMBL)
FBtr0070669(Ensembl_TRS)	74872722(GI)
NSUN2(Synonym)	Nsun2{ECO:0000303\|PubMed:22541559,ECO:0000312\|FlyBase:FBgn0026079}(Symbol)
FBgn0026079(FlyBase)	FBpp0070637(Ensembl_PRO)
NSUN2_DROME(UniProtKB-ID)	45064(GeneID)
NM_143750(refSeq)	O97427(AltAccession)
FBgn0026079(Ensembl)	2.1.1.203 {ECO:0000269\|PubMed:22541559}(EC)
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PANTHER Classification

PANTHER Family:	NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING (PTHR22808)
PANTHER Subfamily:	RNA CYTOSINE-C(5)-METHYLTRANSFERASE NSUN2-RELATED (PTHR22808:SF1)
PANTHER GO-slim Molecular Function:	methyltransferase activity
PANTHER GO-slim Biological Process:	RNA methylation
PANTHER GO-slim Cellular Component:
PANTHER protein class:	RNA methyltransferase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	RNA binding, tRNA (cytidine-5-)-methyltransferase activity, tRNA binding
GO BP Complete:	RNA methylation, short-term memory, tRNA methylation
GO CC Complete:	nucleus, cytoplasm, mitochondrion, nucleolus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
MOUSE\|MGI=MGI=1919431\|UniProtKB=C4P6S0	Mus musculus	O
PIG\|Ensembl=ENSSSCG00000045959.1\|UniProtKB=A0A5G2QJQ4	Sus scrofa	O
HUMAN\|HGNC=25994\|UniProtKB=Q08J23	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000016715.6\|UniProtKB=H2R3L8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000016583.3\|UniProtKB=A0A2I2Z719	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000002561.4\|UniProtKB=F6XQN4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=107252\|UniProtKB=Q1HFZ0	Mus musculus	LDO
RAT\|RGD=1311954\|UniProtKB=D4A3S8	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015466.6\|UniProtKB=F1MK61	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000017104.5\|UniProtKB=A0A5G2QSP5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000016357.4\|UniProtKB=F6X1V6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000015602.6\|UniProtKB=A0A2I2UHX9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845023886.1\|UniProtKB=A0A8I3PU93	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000002039.4\|UniProtKB=F6QCU8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000009243.4\|UniProtKB=A0A6I8PG56	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010000653.1\|UniProtKB=A0A8V0X3G6	Gallus gallus	LDO
CHICK\|Gene_ORFName=RCJMB04_4l11\|UniProtKB=Q5ZLV4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000000677.4\|UniProtKB=G1K8Q2	Anolis carolinensis	LDO
XENLA\|Gene=nsun2.S\|UniProtKB=A0A1L8FS47	Xenopus laevis	LDO
XENLA\|Gene=nsun2\|UniProtKB=Q4V7N2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-962623\|UniProtKB=Q28E61	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000014332.3\|UniProtKB=H2MH74	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-4017\|UniProtKB=A5PMI3	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000008755.1\|UniProtKB=W5MQK5	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000009504.3\|UniProtKB=F6XKA2	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118417640\|UniProtKB=A0A9J7LAE9	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC592875\|UniProtKB=A0A7M7N620	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00021686\|UniProtKB=Q9BL15	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG08493\|UniProtKB=A8X6P7	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00094468\|UniProtKB=A0A2A6CEU5	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00277941\|UniProtKB=A0A2A6CE53	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00277970\|UniProtKB=A0A2A6CEP2	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP002504\|UniProtKB=Q5TTT3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC009472\|UniProtKB=D6WRF5	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_329423\|UniProtKB=E9HGJ5	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG68497\|UniProtKB=T1FZF8	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g20689\|UniProtKB=A7SAM8	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG19981\|UniProtKB=B3RJG2	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_36363\|UniProtKB=A9UV72	Monosiga brevicollis	LDO
YEAST\|SGD=S000000120\|UniProtKB=P38205	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR179C\|UniProtKB=Q753Z3	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000192993\|UniProtKB=A0A1D8PSR2	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E06765g\|UniProtKB=Q6C6S1	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_00757\|UniProtKB=C8VQX6	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G14180\|UniProtKB=Q4WS32	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU05301\|UniProtKB=Q7S8Z9	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_03008\|UniProtKB=A7ECG9	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_06412\|UniProtKB=Q0UPA2	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC17D4.04\|UniProtKB=Q9HGQ2	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_00325\|UniProtKB=B6JVB8	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPAC23C4.17\|UniProtKB=O13935	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02099\|UniProtKB=B6JZQ4	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CND00130\|UniProtKB=Q5KJ97	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_05126\|UniProtKB=A0A0D1C9P1	Ustilago maydis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_13651\|UniProtKB=F4PA94	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_140970\|UniProtKB=C4M504	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_098500\|UniProtKB=C4LXD0	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_103830\|UniProtKB=C4LVM5	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0295715\|UniProtKB=C7G023	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_30335\|UniProtKB=F0ZF65	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_29_2540\|UniProtKB=E9AEB6	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.3.3230\|UniProtKB=Q57V63	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_18_1110\|UniProtKB=Q4QDT1	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.389.0530\|UniProtKB=Q388U8	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_17_1130\|UniProtKB=Q4QE78	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.5.2420\|UniProtKB=Q582C3	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_32_3570\|UniProtKB=Q4Q4R4	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.01.8230\|UniProtKB=Q381D3	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_36_2170\|UniProtKB=Q4Q1K4	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.70.0080\|UniProtKB=Q38AT8	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_17199\|UniProtKB=A8BIF9	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_079770\|UniProtKB=A2EFA7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_427320\|UniProtKB=A2FNB4	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_380890\|UniProtKB=A2FUH6	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_0704200\|UniProtKB=Q8IC28	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00013766001\|UniProtKB=A0D5L9	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00018463001\|UniProtKB=A0DMH8	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_20737\|UniProtKB=B8BQE4	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_23686\|UniProtKB=B8C6H7	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_39812\|UniProtKB=B8BX78	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GSM6_PHYRM\|UniProtKB=H3GSM6	Phytophthora ramorum	LDO
PHYRM\|Gene=H3GM61_PHYRM\|UniProtKB=H3GM61	Phytophthora ramorum	O
PHYRM\|Gene=H3GM63_PHYRM\|UniProtKB=H3GM63	Phytophthora ramorum	O
PHYRM\|Gene=H3GME8_PHYRM\|UniProtKB=H3GME8	Phytophthora ramorum	O
PHYRM\|Gene=H3HAP2_PHYRM\|UniProtKB=H3HAP2	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_03g179860v5\|UniProtKB=A0A2K3DXQ0	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00008p00028880\|UniProtKB=W1NJC3	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_25G00830\|UniProtKB=A0A0K9PFF5	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma07_g20520\|UniProtKB=A0A804JXV0	Musa acuminata subsp. malaccensis	LDO
SORBI\|EnsemblGenome=SORBI_3007G225800\|UniProtKB=A0A1B6PJA7	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb033550\|UniProtKB=A0A804LSL6	Zea mays	O
ORYSJ\|EnsemblGenome=Os08g0484400\|UniProtKB=Q6YTT4	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g38655v3\|UniProtKB=A0A0Q3M2G1	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0339590\|UniProtKB=A0A8I6XCA5	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS4A02G254100\|UniProtKB=A0A3B6HVQ8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4B02G060400\|UniProtKB=A0A3B6ILW2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4D02G060100\|UniProtKB=A0A3B6JFY1	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_028901mg\|UniProtKB=K3ZQM1	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G234300\|UniProtKB=C5X327	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb315780\|UniProtKB=A0A1D6I6D3	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os09g0471900\|UniProtKB=Q0J106	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g32840v3\|UniProtKB=I1IQZ1	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0488290\|UniProtKB=A0A8I6XTH8	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5D02G256900\|UniProtKB=A0A3B6MUC8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G247600\|UniProtKB=A0A3B6LNM8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G249700\|UniProtKB=A0A3B6KHA8	Triticum aestivum	LDO
NELNU\|Gene=LOC104604502\|UniProtKB=A0A1U8AM88	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110791853\|UniProtKB=A0A9R0IQB0	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr07g0196311\|UniProtKB=A0A251UCC0	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr12g0555631\|UniProtKB=A0A9K3MX91	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C500245120\|UniProtKB=A0A9R1VFQ3	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a001393mg\|UniProtKB=A0A022QTU2	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_15043\|UniProtKB=A0A1U8GPL0	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc05g051520.3\|UniProtKB=A0A3Q7GNH2	Solanum lycopersicum	O
TOBAC\|Gene=LOC107766522\|UniProtKB=A0A1S3XLU7	Nicotiana tabacum	O
TOBAC\|Gene=LOC107808849\|UniProtKB=A0A1S4BJ32	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_29362\|UniProtKB=A0A2G2Y5A0	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400016157\|UniProtKB=M1BBS0	Solanum tuberosum	LDO
TOBAC\|Gene=LOC107822797\|UniProtKB=A0A1S4CUP4	Nicotiana tabacum	O
TOBAC\|Gene=LOC107802160\|UniProtKB=A0A1S4AWM5	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi07g01503\|UniProtKB=D7TRL1	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_H04746\|UniProtKB=A0A059B864	Eucalyptus grandis	LDO
BRANA\|EnsemblGenome=GSBRNA2T00072104001\|UniProtKB=A0A078JP96	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra011816\|UniProtKB=M4D5Q9	Brassica campestris	LDO
ARATH\|TAIR=locus=2140094\|UniProtKB=F4JJ52	Arabidopsis thaliana	LDO
BRANA\|Gene_ORFName=DARMORV10_A09P57600.1\|UniProtKB=A0A078FH61	Brassica napus	O
BRACM\|EnsemblGenome=Bra038528\|UniProtKB=M4FBR2	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A04P16880.1\|UniProtKB=A0A078GLX2	Brassica napus	O
BRACM\|EnsemblGenome=Bra030242\|UniProtKB=M4EN72	Brassica campestris	O
ARATH\|TAIR=locus=2041213\|UniProtKB=Q8L601	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107950435\|UniProtKB=A0A1U8NRS1	Gossypium hirsutum	O
GOSHI\|Gene=LOC107951730\|UniProtKB=A0A1U8NWA4	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_001055\|UniProtKB=A0A061DHQ5	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g004759mg\|UniProtKB=A0A067F067	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_007G096100v3\|UniProtKB=A0A2K1ZRV6	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_12G131000\|UniProtKB=A0A2C9UW32	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0768090\|UniProtKB=B9T0A2	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_11G241400\|UniProtKB=I1LNJ4	Glycine max	O
MEDTR\|EnsemblGenome=MTR_3g086950\|UniProtKB=G7J386	Medicago truncatula	O
SOYBN\|EnsemblGenome=GLYMA_05G176200\|UniProtKB=A0A368UJQ1	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G133700\|UniProtKB=I1KSZ0	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_8g089980\|UniProtKB=A0A072TUE4	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr01_17160\|UniProtKB=A0A6P9ELR8	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_6G499770\|UniProtKB=A0A0A0KGQ7	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_6G191700\|UniProtKB=A0A251NSQ4	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_120643\|UniProtKB=D8SN08	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_418525\|UniProtKB=D8S5Z9	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c15_5210\|UniProtKB=A0A2K1JC36	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0022s0008\|UniProtKB=A0A2R6XCR6	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_003870100\|UniProtKB=A0A1Y1IBH1	Klebsormidium nitens	LDO