PANTHER Gene Information

Gene Symbol(s):

NSUN2

Organism:

Pan troglodytes

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Gene Name:

tRNA (cytosine(34)-C(5))-methyltransferase

Gene ID:

ENSPTRG00000016715.6

Protein ID:

H2R3L8

Persistent Id:

PTN000516092

Alternate Ids:

461711(GeneID)	GABF01001728(EMBL)
ENSPTRT00000045008(Ensembl_TRS)	ENSPTRP00000070301(Ensembl_PRO)
JAA20417(EMBL-CDS)	H2R3L8(Synonym)
1034167644(GI)	ENSPTRG00000016715(Ensembl)
H2R3L8_PANTR(UniProtKB-ID)	XP_016808417(refSeq)
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PANTHER Classification

PANTHER Family:	NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING (PTHR22808)
PANTHER Subfamily:	RNA CYTOSINE C(5)-METHYLTRANSFERASE NSUN2 (PTHR22808:SF20)
PANTHER GO-slim Molecular Function:	tRNA methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity tRNA binding
PANTHER GO-slim Biological Process:	tRNA methylation
PANTHER GO-slim Cellular Component:	nucleus cytoplasm
PANTHER protein class:	RNA methyltransferase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	RNA methyltransferase activity, RNA binding, tRNA (cytidine-5-)-methyltransferase activity, mRNA (cytidine-5-)-methyltransferase activity, methyltransferase activity, tRNA binding, S-adenosylmethionine-dependent methyltransferase activity
GO BP Complete:	RNA methylation, in utero embryonic development, spermatid development, tRNA processing, regulation of stem cell differentiation, meiotic cell cycle checkpoint signaling, tRNA stabilization, mRNA processing, hair follicle maturation, tRNA methylation, regulation of mRNA export from nucleus, methylation
GO CC Complete:	nucleus, chromatoid body, extracellular exosome, cytoplasm, mitochondrion, extracellular region, nucleolus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=25994\|UniProtKB=Q08J23	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000016583.3\|UniProtKB=A0A2I2Z719	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000002561.4\|UniProtKB=F6XQN4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=107252\|UniProtKB=Q1HFZ0	Mus musculus	LDO
RAT\|RGD=1311954\|UniProtKB=D4A3S8	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015466.6\|UniProtKB=F1MK61	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000017104.5\|UniProtKB=A0A5G2QSP5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000016357.4\|UniProtKB=F6X1V6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000015602.6\|UniProtKB=A0A2I2UHX9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845023886.1\|UniProtKB=A0A8I3PU93	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000002039.4\|UniProtKB=F6QCU8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000009243.4\|UniProtKB=A0A6I8PG56	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010000653.1\|UniProtKB=A0A8V0X3G6	Gallus gallus	LDO
CHICK\|Gene_ORFName=RCJMB04_4l11\|UniProtKB=Q5ZLV4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000000677.4\|UniProtKB=G1K8Q2	Anolis carolinensis	LDO
XENLA\|Gene=nsun2.S\|UniProtKB=A0A1L8FS47	Xenopus laevis	LDO
XENLA\|Gene=nsun2\|UniProtKB=Q4V7N2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-962623\|UniProtKB=Q28E61	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000014332.3\|UniProtKB=H2MH74	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-4017\|UniProtKB=A5PMI3	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000008755.1\|UniProtKB=W5MQK5	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000009504.3\|UniProtKB=F6XKA2	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118417640\|UniProtKB=A0A9J7LAE9	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC592875\|UniProtKB=A0A7M7N620	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00021686\|UniProtKB=Q9BL15	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG08493\|UniProtKB=A8X6P7	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00094468\|UniProtKB=A0A2A6CEU5	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00277941\|UniProtKB=A0A2A6CE53	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00277970\|UniProtKB=A0A2A6CEP2	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0026079\|UniProtKB=Q9W4M9	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002504\|UniProtKB=Q5TTT3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC009472\|UniProtKB=D6WRF5	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_329423\|UniProtKB=E9HGJ5	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG68497\|UniProtKB=T1FZF8	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g20689\|UniProtKB=A7SAM8	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG19981\|UniProtKB=B3RJG2	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_36363\|UniProtKB=A9UV72	Monosiga brevicollis	LDO
YEAST\|SGD=S000000120\|UniProtKB=P38205	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR179C\|UniProtKB=Q753Z3	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000192993\|UniProtKB=A0A1D8PSR2	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E06765g\|UniProtKB=Q6C6S1	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_00757\|UniProtKB=C8VQX6	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G14180\|UniProtKB=Q4WS32	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU05301\|UniProtKB=Q7S8Z9	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_03008\|UniProtKB=A7ECG9	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_06412\|UniProtKB=Q0UPA2	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC17D4.04\|UniProtKB=Q9HGQ2	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_00325\|UniProtKB=B6JVB8	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPAC23C4.17\|UniProtKB=O13935	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02099\|UniProtKB=B6JZQ4	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CND00130\|UniProtKB=Q5KJ97	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_05126\|UniProtKB=A0A0D1C9P1	Ustilago maydis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_13651\|UniProtKB=F4PA94	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_140970\|UniProtKB=C4M504	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_098500\|UniProtKB=C4LXD0	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_103830\|UniProtKB=C4LVM5	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0295715\|UniProtKB=C7G023	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_30335\|UniProtKB=F0ZF65	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_29_2540\|UniProtKB=E9AEB6	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.3.3230\|UniProtKB=Q57V63	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_18_1110\|UniProtKB=Q4QDT1	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.389.0530\|UniProtKB=Q388U8	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_17_1130\|UniProtKB=Q4QE78	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.5.2420\|UniProtKB=Q582C3	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_32_3570\|UniProtKB=Q4Q4R4	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.01.8230\|UniProtKB=Q381D3	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_36_2170\|UniProtKB=Q4Q1K4	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.70.0080\|UniProtKB=Q38AT8	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_17199\|UniProtKB=A8BIF9	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_079770\|UniProtKB=A2EFA7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_427320\|UniProtKB=A2FNB4	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_380890\|UniProtKB=A2FUH6	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_0704200\|UniProtKB=Q8IC28	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00013766001\|UniProtKB=A0D5L9	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00018463001\|UniProtKB=A0DMH8	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_20737\|UniProtKB=B8BQE4	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_23686\|UniProtKB=B8C6H7	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_39812\|UniProtKB=B8BX78	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GSM6_PHYRM\|UniProtKB=H3GSM6	Phytophthora ramorum	LDO
PHYRM\|Gene=H3GM61_PHYRM\|UniProtKB=H3GM61	Phytophthora ramorum	O
PHYRM\|Gene=H3GM63_PHYRM\|UniProtKB=H3GM63	Phytophthora ramorum	O
PHYRM\|Gene=H3GME8_PHYRM\|UniProtKB=H3GME8	Phytophthora ramorum	O
PHYRM\|Gene=H3HAP2_PHYRM\|UniProtKB=H3HAP2	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_03g179860v5\|UniProtKB=A0A2K3DXQ0	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00008p00028880\|UniProtKB=W1NJC3	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_25G00830\|UniProtKB=A0A0K9PFF5	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma07_g20520\|UniProtKB=A0A804JXV0	Musa acuminata subsp. malaccensis	LDO
SORBI\|EnsemblGenome=SORBI_3007G225800\|UniProtKB=A0A1B6PJA7	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb033550\|UniProtKB=A0A804LSL6	Zea mays	O
ORYSJ\|EnsemblGenome=Os08g0484400\|UniProtKB=Q6YTT4	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g38655v3\|UniProtKB=A0A0Q3M2G1	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0339590\|UniProtKB=A0A8I6XCA5	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS4A02G254100\|UniProtKB=A0A3B6HVQ8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4B02G060400\|UniProtKB=A0A3B6ILW2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4D02G060100\|UniProtKB=A0A3B6JFY1	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_028901mg\|UniProtKB=K3ZQM1	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G234300\|UniProtKB=C5X327	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb315780\|UniProtKB=A0A1D6I6D3	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os09g0471900\|UniProtKB=Q0J106	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g32840v3\|UniProtKB=I1IQZ1	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0488290\|UniProtKB=A0A8I6XTH8	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5D02G256900\|UniProtKB=A0A3B6MUC8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G247600\|UniProtKB=A0A3B6LNM8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G249700\|UniProtKB=A0A3B6KHA8	Triticum aestivum	LDO
NELNU\|Gene=LOC104604502\|UniProtKB=A0A1U8AM88	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110791853\|UniProtKB=A0A9R0IQB0	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr07g0196311\|UniProtKB=A0A251UCC0	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr12g0555631\|UniProtKB=A0A9K3MX91	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C500245120\|UniProtKB=A0A9R1VFQ3	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a001393mg\|UniProtKB=A0A022QTU2	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_15043\|UniProtKB=A0A1U8GPL0	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc05g051520.3\|UniProtKB=A0A3Q7GNH2	Solanum lycopersicum	O
TOBAC\|Gene=LOC107766522\|UniProtKB=A0A1S3XLU7	Nicotiana tabacum	O
TOBAC\|Gene=LOC107808849\|UniProtKB=A0A1S4BJ32	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_29362\|UniProtKB=A0A2G2Y5A0	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400016157\|UniProtKB=M1BBS0	Solanum tuberosum	LDO
TOBAC\|Gene=LOC107822797\|UniProtKB=A0A1S4CUP4	Nicotiana tabacum	O
TOBAC\|Gene=LOC107802160\|UniProtKB=A0A1S4AWM5	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi07g01503\|UniProtKB=D7TRL1	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_H04746\|UniProtKB=A0A059B864	Eucalyptus grandis	LDO
BRANA\|EnsemblGenome=GSBRNA2T00072104001\|UniProtKB=A0A078JP96	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra011816\|UniProtKB=M4D5Q9	Brassica campestris	LDO
ARATH\|TAIR=locus=2140094\|UniProtKB=F4JJ52	Arabidopsis thaliana	LDO
BRANA\|Gene_ORFName=DARMORV10_A09P57600.1\|UniProtKB=A0A078FH61	Brassica napus	O
BRACM\|EnsemblGenome=Bra038528\|UniProtKB=M4FBR2	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A04P16880.1\|UniProtKB=A0A078GLX2	Brassica napus	O
BRACM\|EnsemblGenome=Bra030242\|UniProtKB=M4EN72	Brassica campestris	O
ARATH\|TAIR=locus=2041213\|UniProtKB=Q8L601	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107950435\|UniProtKB=A0A1U8NRS1	Gossypium hirsutum	O
GOSHI\|Gene=LOC107951730\|UniProtKB=A0A1U8NWA4	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_001055\|UniProtKB=A0A061DHQ5	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g004759mg\|UniProtKB=A0A067F067	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_007G096100v3\|UniProtKB=A0A2K1ZRV6	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_12G131000\|UniProtKB=A0A2C9UW32	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0768090\|UniProtKB=B9T0A2	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_11G241400\|UniProtKB=I1LNJ4	Glycine max	O
MEDTR\|EnsemblGenome=MTR_3g086950\|UniProtKB=G7J386	Medicago truncatula	O
SOYBN\|EnsemblGenome=GLYMA_05G176200\|UniProtKB=A0A368UJQ1	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G133700\|UniProtKB=I1KSZ0	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_8g089980\|UniProtKB=A0A072TUE4	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr01_17160\|UniProtKB=A0A6P9ELR8	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_6G499770\|UniProtKB=A0A0A0KGQ7	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_6G191700\|UniProtKB=A0A251NSQ4	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_120643\|UniProtKB=D8SN08	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_418525\|UniProtKB=D8S5Z9	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c15_5210\|UniProtKB=A0A2K1JC36	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0022s0008\|UniProtKB=A0A2R6XCR6	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_003870100\|UniProtKB=A0A1Y1IBH1	Klebsormidium nitens	LDO