PANTHER Gene Information   
Gene Symbol(s): APC7
Organism: Drosophila melanogaster
View Gene in Tree
Tree Reduced Tree  
Tree Reduced Tree
Gene Name: Anaphase promoting complex subunit 7, isoform A
Gene ID: FBgn0029879
Protein ID: Q9W3Y6
Persistent Id: PTN000285221
Alternate Ids:
FBgn0029879(FlyBase) 31594(GeneID)
FBtr0070946(Ensembl_TRS) FBpp0070907(Ensembl_PRO)
AE014298(EMBL) Q9W3Y6(Synonym)
FBgn0029879(Ensembl) AAF46175(EMBL-CDS)
NP_572329(refSeq) 45446825(GI)
Q9W3Y6_DROME(UniProtKB-ID)
Show All

PANTHER Classification
PANTHER Family: CELL DIVISION CYCLE 16,23,27 (PTHR12558)
PANTHER Subfamily: ANAPHASE-PROMOTING COMPLEX SUBUNIT 7 (PTHR12558:SF36)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process: cell division
positive regulation of mitotic cell cycle
regulation of mitotic sister chromatid separation
positive regulation of mitotic nuclear division
protein ubiquitination
regulation of mitotic metaphase/anaphase transition
PANTHER GO-slim Cellular Component: anaphase-promoting complex
PANTHER protein class: ubiquitin-protein ligase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: -
GO BP Complete: cell division, positive regulation of mitotic metaphase/anaphase transition, protein ubiquitination
GO CC Complete: anaphase-promoting complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: APC/C:Cdc20 mediated degradation of mitotic proteins, Cellular Senescence, Regulation of APC/C activators between G1/S and early anaphase, Senescence-Associated Secretory Phenotype (SASP), Switching of origins to a post-replicative state, Cellular responses to stress, APC/C:Cdc20 mediated degradation of Cyclin B, Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase, APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint, Autodegradation of Cdh1 by Cdh1:APC/C, Cdc20:Phospho-APC/C mediated degradation of Cyclin A, APC/C-mediated degradation of cell cycle proteins, DNA Replication, Cellular responses to stimuli, Cell Cycle Checkpoints, Mitotic Metaphase and Anaphase, Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components, S Phase, Separation of Sister Chromatids, Class I MHC mediated antigen processing & presentation, Inactivation of APC/C via direct inhibition of the APC/C complex, Cell Cycle, Immune System, Antigen processing: Ubiquitination & Proteasome degradation, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, Phosphorylation of the APC/C, Adaptive Immune System, APC-Cdc20 mediated degradation of Nek2A, Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, Regulation of mitotic cell cycle, Mitotic Spindle Checkpoint, Synthesis of DNA, M Phase, APC/C:Cdc20 mediated degradation of Securin, Cell Cycle, Mitotic, Mitotic Anaphase, CDK-mediated phosphorylation and removal of Cdc6

Orthologs