PANTHER Gene Information   
Gene Symbol(s): ANAPC7
Organism: Sus scrofa
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Gene Name: Anaphase promoting complex subunit 7
Gene ID: ENSSSCG00000030222.4
Protein ID: I3L7Q8
Persistent Id: PTN001395182
Alternate Ids:
ENSSSCP00000020064(Ensembl_PRO) I3L7Q8(Synonym)
927204767(GI) XP_001929442(refSeq)
ENSSSCT00000028521(Ensembl_TRS) ENSSSCG00000030222(Ensembl)
I3L7Q8_PIG(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: CELL DIVISION CYCLE 16,23,27 (PTHR12558)
PANTHER Subfamily: ANAPHASE-PROMOTING COMPLEX SUBUNIT 7 (PTHR12558:SF36)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process: cell division
positive regulation of mitotic cell cycle
regulation of mitotic sister chromatid separation
positive regulation of mitotic nuclear division
protein ubiquitination
regulation of mitotic metaphase/anaphase transition
PANTHER GO-slim Cellular Component: anaphase-promoting complex
PANTHER protein class: ubiquitin-protein ligase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein phosphatase binding, enzyme-substrate adaptor activity
GO BP Complete: cell division, protein K11-linked ubiquitination, protein K48-linked ubiquitination, anaphase-promoting complex-dependent catabolic process, positive regulation of mitotic metaphase/anaphase transition, brain development, protein branched polyubiquitination, protein ubiquitination
GO CC Complete: heterochromatin, anaphase-promoting complex, spindle
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components, Regulation of mitotic cell cycle, DNA Replication, APC/C:Cdc20 mediated degradation of mitotic proteins, Adaptive Immune System, Regulation of APC/C activators between G1/S and early anaphase, Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase, APC-Cdc20 mediated degradation of Nek2A, Senescence-Associated Secretory Phenotype (SASP), DNA Replication Pre-Initiation, S Phase, APC/C:Cdc20 mediated degradation of Cyclin B, Cell Cycle Checkpoints, Cellular Senescence, APC/C-mediated degradation of cell cycle proteins, Cdc20:Phospho-APC/C mediated degradation of Cyclin A, Autodegradation of Cdh1 by Cdh1:APC/C, Assembly of the pre-replicative complex, Synthesis of DNA, APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint, Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, Mitotic Spindle Checkpoint, Cell Cycle, Mitotic, Mitotic Anaphase, Cellular responses to stress, CDK-mediated phosphorylation and removal of Cdc6, Immune System, Cell Cycle, Phosphorylation of the APC/C, M Phase, Antigen processing: Ubiquitination & Proteasome degradation, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, Class I MHC mediated antigen processing & presentation, Mitotic Metaphase and Anaphase, APC/C:Cdc20 mediated degradation of Securin, Inactivation of APC/C via direct inhibition of the APC/C complex, Cellular responses to stimuli, Separation of Sister Chromatids, Switching of origins to a post-replicative state

Orthologs