PANTHER Gene Information

Gene Symbol(s):

srlD

Organism:

Escherichia coli

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Gene Name:

Sorbitol-6-phosphate 2-dehydrogenase

Gene ID:

BAA16566

Protein ID:

P05707

Persistent Id:

PTN001292941

Alternate Ids:

srlD(Symbol)	BAA16566(Ensembl_TRS)
BAA16566(Ensembl)	Ketosephosphate reductase(Synonym)
808701385(GI)	AAC13413(EMBL-CDS)
SRLD_ECOLI(UniProtKB-ID)	J02708(EMBL)
MetaCyc:SORB6PDEHYDROG-MON(BioCyc)	NC_000913(refSeq)
AAC75747(Ensembl_PRO)	1.1.1.140 {ECO:0000269\|PubMed:6384188}(EC)
75205946(GeneID)
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PANTHER Classification

PANTHER Family:	SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (PTHR42760)
PANTHER Subfamily:	SORBITOL-6-PHOSPHATE 2-DEHYDROGENASE (PTHR42760:SF105)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	oxidoreductase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	identical protein binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, oxidoreductase activity, sorbitol-6-phosphate 2-dehydrogenase activity
GO BP Complete:	protein homotetramerization, sorbitol catabolic process
GO CC Complete:	protein-containing complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
MONBE\|EnsemblGenome=MONBRDRAFT_10960\|UniProtKB=A9V7S3	Monosiga brevicollis	O
EMENI\|EnsemblGenome=ANIA_10933\|UniProtKB=C8VCG4	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_10005\|UniProtKB=C8VRG1	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G00750\|UniProtKB=Q4WFW9	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU08784\|UniProtKB=U9W3Q4	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_06517\|UniProtKB=A7EMG9	Sclerotinia sclerotiorum	O
SCLS1\|EnsemblGenome=SS1G_05581\|UniProtKB=A7EJT6	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_15354\|UniProtKB=Q0TYS8	Phaeosphaeria nodorum	O
KORCO\|EnsemblGenome=Kcr_0600\|UniProtKB=B1L4H4	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO2664\|UniProtKB=Q97VG2	Sulfolobus solfataricus	O
HUMAN\|HGNC=3554\|UniProtKB=Q92506	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000018036.2\|UniProtKB=H2QSS7	Pan troglodytes	O
MACMU\|Ensembl=ENSMMUG00000003861.4\|UniProtKB=Q8WMN4	Macaca mulatta	O
MOUSE\|MGI=MGI=95911\|UniProtKB=P50171	Mus musculus	O
RAT\|RGD=1303158\|UniProtKB=Q6MGB5	Rattus norvegicus	O
PIG\|Ensembl=ENSSSCG00000001476.6\|UniProtKB=K7GLG0	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000058465.1\|UniProtKB=A0A5F5PX36	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000006986.5\|UniProtKB=M3W6V5	Felis catus	O
BOVIN\|Ensembl=ENSBTAG00000020927.5\|UniProtKB=Q32S21	Bos taurus	O
PIG\|Gene=HSD17B8\|UniProtKB=Q9XT00	Sus scrofa	O
CANLF\|Ensembl=ENSCAFG00845020603\|UniProtKB=Q5TJF5	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000014232.3\|UniProtKB=F6T964	Monodelphis domestica	O
CHICK\|Ensembl=ENSGALG00010001700.1\|UniProtKB=A0A8V0X6I6	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010001642.1\|UniProtKB=A0A8V0XCB1	Gallus gallus	O
XENLA\|Gene=hsd17b8.S\|UniProtKB=A0A1L8F3J7	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-490296\|UniProtKB=Q28IT0	Xenopus tropicalis	O
DANRE\|ZFIN=ZDB-GENE-010110-1\|UniProtKB=Q561S1	Danio rerio	O
CIOIN\|Ensembl=ENSCING00000022654.1\|UniProtKB=H2XRG7	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000001307.2\|UniProtKB=F6WW36	Ciona intestinalis	O
BRAFL\|Gene=LOC118422026\|UniProtKB=A0A9J7LM35	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418417\|UniProtKB=A0A9J7MTA6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118420782\|UniProtKB=A0A9J7LIN5	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC592790\|UniProtKB=A0A7M7PLZ7	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00000988\|UniProtKB=Q19246	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00037777\|UniProtKB=A8XSG5	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00042605\|UniProtKB=A8WKV7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00107010\|UniProtKB=A0A2A6B4M3	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0029648\|UniProtKB=Q9W4U2	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009633\|UniProtKB=Q7Q1U0	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_231057\|UniProtKB=E9GN45	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW003821\|UniProtKB=B7PG28	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW017020\|UniProtKB=B7PA67	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW007844\|UniProtKB=B7PSR3	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW012432\|UniProtKB=B7QBJ7	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW013147\|UniProtKB=B7QCE4	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW016683\|UniProtKB=B7P8S3	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW002297\|UniProtKB=B7PAW7	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW007527\|UniProtKB=B7PX50	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW001832\|UniProtKB=B7PC62	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW001580\|UniProtKB=B7P335	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW004591\|UniProtKB=B7PHS8	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW002164\|UniProtKB=B7P9E2	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW023711\|UniProtKB=B7QHU9	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW017021\|UniProtKB=B7PA68	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW015306\|UniProtKB=B7QMN2	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW013859\|UniProtKB=B7QLV4	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW023710\|UniProtKB=A0A1S4M4F6	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g241360\|UniProtKB=A7RXH2	Nematostella vectensis	O
EMENI\|EnsemblGenome=ANIA_01886\|UniProtKB=Q5BC44	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_04186\|UniProtKB=Q5B5J4	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_7G04360\|UniProtKB=Q4WGA6	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU09035\|UniProtKB=Q7S2U0	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_10326\|UniProtKB=A7EYB1	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_08985\|UniProtKB=Q0UGX9	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_14192\|UniProtKB=Q0U229	Phaeosphaeria nodorum	O
CRYNJ\|EnsemblGenome=CNB05760\|UniProtKB=Q5KLC5	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_11693\|UniProtKB=A0A0D1E7P8	Ustilago maydis	O
THAPS\|EnsemblGenome=THAPSDRAFT_268493\|UniProtKB=B8BXZ7	Thalassiosira pseudonana	O
HUMAN\|HGNC=25891\|UniProtKB=Q8N4T8	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000016585.6\|UniProtKB=H2R3K8	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000024424.2\|UniProtKB=G3S604	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000015921.4\|UniProtKB=G7MSA6	Macaca mulatta	O
MOUSE\|MGI=MGI=2384567\|UniProtKB=Q91VT4	Mus musculus	O
RAT\|RGD=727826\|UniProtKB=Q7TS56	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000022013\|UniProtKB=A4IFA7	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000009717.5\|UniProtKB=F1RIX8	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000022089.3\|UniProtKB=F6XFP1	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000030280.4\|UniProtKB=M3WYQ7	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845026026.1\|UniProtKB=A0A8I3PWZ0	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000040132.1\|UniProtKB=A0A5F8H135	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000007445.4\|UniProtKB=A0A6I8N649	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010008007.1\|UniProtKB=A0A8V0XZX3	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000015942.4\|UniProtKB=H9GMS0	Anolis carolinensis	O
XENLA\|Gene=cbr4\|UniProtKB=Q6NUE2	Xenopus laevis	O
XENLA\|Gene=cbr4.L\|UniProtKB=A0A1L8HU70	Xenopus laevis	O
XENTR\|Gene=cbr4\|UniProtKB=Q68ER2	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000000359.2\|UniProtKB=H2L3W0	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040426-1796\|UniProtKB=Q6P0H7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000013078.1\|UniProtKB=W5N649	lepisosteus oculatus	O
BRAFL\|Gene=LOC118409306\|UniProtKB=A0A9J7HXF9	Branchiostoma floridae	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g144654\|UniProtKB=A7T3R4	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG34673\|UniProtKB=B3SET7	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_19102\|UniProtKB=A9UPE4	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_38805\|UniProtKB=A9VA88	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_37492\|UniProtKB=A9V229	Monosiga brevicollis	O
CANAL\|CGD=CAL0000193195\|UniProtKB=Q5AEJ7	Candida albicans	O
EMENI\|EnsemblGenome=ANIA_06918\|UniProtKB=Q5AXR2	Emericella nidulans	O
CRYNJ\|EnsemblGenome=CNB02490\|UniProtKB=Q5KM93	Cryptococcus neoformans	O
YEAST\|SGD=S000001538\|UniProtKB=P35731	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ABR076C\|UniProtKB=Q75DF0	Eremothecium gossypii	O
CANAL\|CGD=CAL0000194659\|UniProtKB=Q5A845	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F29975g\|UniProtKB=Q6BZY3	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_D05929g\|UniProtKB=Q6CA49	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_C19965g\|UniProtKB=Q6CBC8	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_05373\|UniProtKB=C8VGQ1	Emericella nidulans	O
NEUCR\|EnsemblGenome=NCU01092\|UniProtKB=Q1K883	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_01685\|UniProtKB=A7E8Q7	Sclerotinia sclerotiorum	O
EMENI\|EnsemblGenome=ANIA_10308\|UniProtKB=C8VP66	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G10520\|UniProtKB=Q4WMB2	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03525\|UniProtKB=Q1K5E4	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_07263\|UniProtKB=Q0ULV1	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_01822\|UniProtKB=Q5BCA8	Emericella nidulans	O
PHANO\|EnsemblGenome=SNOG_03237\|UniProtKB=Q0UYC7	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_10169\|UniProtKB=C8VSH7	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G10100\|UniProtKB=Q4WT94	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU08943\|UniProtKB=Q1K6S0	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_02741\|UniProtKB=A7EBQ5	Sclerotinia sclerotiorum	O
SCLS1\|Gene_ORFName=SS1G_11891\|UniProtKB=A7F3P5	Sclerotinia sclerotiorum	O
SCLS1\|Gene_ORFName=SS1G_10602\|UniProtKB=A7EZ36	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_00425\|UniProtKB=Q0V6D9	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_04803\|UniProtKB=Q0UTW1	Phaeosphaeria nodorum	O
ASPFU\|EnsemblGenome=AFUA_1G11010\|UniProtKB=Q4WT04	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_7G04980\|UniProtKB=Q4WGG7	Neosartorya fumigata	O
PHANO\|EnsemblGenome=SNOG_08659\|UniProtKB=Q0UHV5	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_12261\|UniProtKB=Q0U7K3	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_06450\|UniProtKB=Q5AZ30	Emericella nidulans	O
SCLS1\|EnsemblGenome=SS1G_12245\|UniProtKB=A7F2U7	Sclerotinia sclerotiorum	O
EMENI\|EnsemblGenome=ANIA_10690\|UniProtKB=C8VG63	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_10122\|UniProtKB=C8VQW0	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G14380\|UniProtKB=E9RBN9	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU00606\|UniProtKB=Q7SI45	Neurospora crassa	O
NEUCR\|EnsemblGenome=NCU09473\|UniProtKB=Q7SC08	Neurospora crassa	O
SCHPO\|PomBase=SPAC3G9.02\|UniProtKB=O42866	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_03198\|UniProtKB=B6K3K8	Schizosaccharomyces japonicus	O
USTMA\|EnsemblGenome=UMAG_10483\|UniProtKB=A0A0D1DX03	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_10252\|UniProtKB=A0A0D1CW98	Ustilago maydis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_15044\|UniProtKB=F4PF77	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_19922\|UniProtKB=F4P5D7	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0269356\|UniProtKB=Q55E82	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_77919\|UniProtKB=F0ZI12	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_27_2440\|UniProtKB=E9ACW4	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.2.5210\|UniProtKB=Q585V0	Trypanosoma brucei	O
PLAF7\|EnsemblGenome=PF3D7_0922900\|UniProtKB=Q8I2S7	Plasmodium falciparum	O
THAPS\|EnsemblGenome=THAPSDRAFT_3848\|UniProtKB=B8BYY5	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_270321\|UniProtKB=B8BTK3	Thalassiosira pseudonana	O
CHLRE\|EnsemblGenome=CHLRE_01g028600v5\|UniProtKB=A8HQC2	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_07g315750v5\|UniProtKB=A8I6B9	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_03g213313v5\|UniProtKB=A8JBX4	Chlamydomonas reinhardtii	O
MEDTR\|EnsemblGenome=MTR_1304s0010\|UniProtKB=A0A072TP88	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_1196s0010\|UniProtKB=A0A072TDE3	Medicago truncatula	O
KLENI\|Gene_ORFName=KFL_001350110\|UniProtKB=A0A1Y1I2V8	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000130610\|UniProtKB=A0A1Y1HRK7	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000680160\|UniProtKB=A0A0U9HJL8	Klebsormidium nitens	O
NITMS\|EnsemblGenome=Nmar_1043\|UniProtKB=A9A3K7	Nitrosopumilus maritimus	O
KORCO\|EnsemblGenome=Kcr_0635\|UniProtKB=B1L4K9	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO2289\|UniProtKB=Q97WD7	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE2089\|UniProtKB=Q8ZVW5	Pyrobaculum aerophilum	O
PYRAE\|EnsemblGenome=PAE1589\|UniProtKB=Q8ZWW4	Pyrobaculum aerophilum	O
PYRAE\|EnsemblGenome=PAE2832\|UniProtKB=Q8ZUD8	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_0107\|UniProtKB=Q8TUG0	Methanosarcina acetivorans	O
HALSA\|EnsemblGenome=VNG_2632G\|UniProtKB=Q9HMA5	Halobacterium salinarum	O
HALSA\|EnsemblGenome=VNG_1341G\|UniProtKB=Q9HQ41	Halobacterium salinarum	O
CLOBH\|Gene_OrderedLocusName=CBO3413\|UniProtKB=A5I7D8	Clostridium botulinum	LDO
RHOBA\|EnsemblGenome=RB9574\|UniProtKB=Q7ULD3	Rhodopirellula baltica	LDO
DICTD\|EnsemblGenome=Dtur_0422\|UniProtKB=B8E1U2	Dictyoglomus turgidum	LDO
SALTY\|EnsemblGenome=STM2835\|UniProtKB=Q8ZMK0	Salmonella typhimurium	LDO