PANTHER Gene Information

Gene Symbol(s):

pepA

Organism:

Escherichia coli

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Gene Name:

Cytosol aminopeptidase

Gene ID:

BAE78257

Protein ID:

P68767

Persistent Id:

PTN000944000

Alternate Ids:

AP009048(EMBL)	446319289(GI)
BAE78257(Ensembl)	AAC77217(Ensembl_TRS)
3.4.11.10(EC)	CAA60164(EMBL-CDS)
NZ_STEB01000013(refSeq)	MetaCyc:EG10694-MON(BioCyc)
AMPA_ECOLI(UniProtKB-ID)	Q2M649(AltAccession)
75203519(GeneID)	LAP(Synonym)
BAE78257(Ensembl_PRO)	pepA(Symbol)
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PANTHER Classification

PANTHER Family:	LEUCINE AMINOPEPTIDASE-RELATED (PTHR11963)
PANTHER Subfamily:	CYTOSOL AMINOPEPTIDASE (PTHR11963:SF23)
PANTHER GO-slim Molecular Function:	peptidase activity
PANTHER GO-slim Biological Process:	proteolysis
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	metalloprotease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, metal ion binding, transcription antitermination factor activity, DNA binding, metalloexopeptidase activity, metalloaminopeptidase activity, aminopeptidase activity, manganese ion binding
GO BP Complete:	peptide catabolic process, plasmid recombination, DNA-templated transcription, proteolysis, transcription antitermination, plasmid maintenance
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
ORYLA\|Ensembl=ENSORLG00000002965.2\|UniProtKB=H2LCR9	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-090312-55\|UniProtKB=Q08CQ0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015639.1\|UniProtKB=W5NF43	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000008044.3\|UniProtKB=F6S5A6	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000004383.3\|UniProtKB=H2Y048	Ciona intestinalis	O
BRAFL\|Gene=LOC118405624\|UniProtKB=A0A9J7HK24	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_130974\|UniProtKB=C3Y3U2	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC590902\|UniProtKB=A0A7M7NW06	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00002250\|UniProtKB=Q27245	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG09450\|UniProtKB=A8X929	Caenorhabditis briggsae	O
DROME\|FlyBase=FBgn0000454\|UniProtKB=Q9VFQ9	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP003475\|UniProtKB=Q7QDE8	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC012824\|UniProtKB=D6X0X1	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_301437\|UniProtKB=E9HIB3	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW003100\|UniProtKB=B7PA58	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g189660\|UniProtKB=A7SGM8	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG64124\|UniProtKB=B3S3I0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG28416\|UniProtKB=B3S3I1	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_33034\|UniProtKB=A9V351	Monosiga brevicollis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_19340\|UniProtKB=F4P0P5	Batrachochytrium dendrobatidis	O
HUMAN\|HGNC=16244\|UniProtKB=Q8NDH3	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000033985.3\|UniProtKB=K7B388	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000012505.3\|UniProtKB=A0A2I2ZDY5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000010006.4\|UniProtKB=H9EU73	Macaca mulatta	O
MOUSE\|MGI=MGI=2448523\|UniProtKB=Q6NSR8	Mus musculus	O
RAT\|RGD=1311351\|UniProtKB=D4A3E2	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000016724.6\|UniProtKB=Q3SWX3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000007517.5\|UniProtKB=A5GFT5	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000022211.4\|UniProtKB=F7B8T0	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000030941.4\|UniProtKB=M3WRF6	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845013592.1\|UniProtKB=A0A8I3NGL3	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000016562.2\|UniProtKB=F7DN69	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000009270.4\|UniProtKB=F7ES05	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010014710.1\|UniProtKB=F1NSZ4	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000005975.4\|UniProtKB=H9GAV6	Anolis carolinensis	O
XENLA\|Gene=npepl1.L\|UniProtKB=Q05AX8	Xenopus laevis	O
XENLA\|Gene=npepl1.S\|UniProtKB=Q52KT0	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5829494\|UniProtKB=Q4VA75	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000014706.2\|UniProtKB=H2MIF7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050417-177\|UniProtKB=Q561T4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000002322.1\|UniProtKB=W5M2Y6	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000006225.1\|UniProtKB=W5MGL2	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000021194.1\|UniProtKB=H2XLM6	Ciona intestinalis	O
BRAFL\|Gene=LOC118417976\|UniProtKB=A0A9J7MTU7	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC575037\|UniProtKB=A0A7M7STZ5	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00002249\|UniProtKB=P34629	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00037619\|UniProtKB=A8XT45	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00204302\|UniProtKB=A0A2A6C706	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00092550\|UniProtKB=A0A8R1U3Z9	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00092558\|UniProtKB=A0A2A6B4V3	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0040493\|UniProtKB=A0A0C4FEI8	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007809\|UniProtKB=A0A1S4GWA0	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC015913\|UniProtKB=D6WTW2	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_307351\|UniProtKB=E9H1Y3	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW023735\|UniProtKB=B7QLQ7	Ixodes scapularis	O
TRIAD\|EnsemblGenome=TriadG37059\|UniProtKB=B3RJ17	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_13001\|UniProtKB=A9VE03	Monosiga brevicollis	O
LEIMA\|EnsemblGenome=LMJF_11_0630\|UniProtKB=Q4QH17	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_11_0620\|UniProtKB=Q4QH18	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.02.4440\|UniProtKB=Q385B0	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_33_2570\|UniProtKB=Q4Q3T0	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.02.0070\|UniProtKB=Q386R3	Trypanosoma brucei	O
THAPS\|EnsemblGenome=THAPSDRAFT_36368\|UniProtKB=B8C9H7	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GZ78_PHYRM\|UniProtKB=H3GZ78	Phytophthora ramorum	O
PANTR\|Ensembl=ENSPTRG00000050938.1\|UniProtKB=A0A2I3RAG2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000025194.2\|UniProtKB=A0A2I2YLC7	Gorilla gorilla gorilla	O
HUMAN\|HGNC=18449\|UniProtKB=P28838	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000015938.3\|UniProtKB=G2HHE6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000001110.4\|UniProtKB=G3QFL8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000005732.4\|UniProtKB=F6TQJ2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1914238\|UniProtKB=Q9CPY7	Mus musculus	LDO
RAT\|RGD=150343158\|UniProtKB=A0A8I6B0E2	Rattus norvegicus	O
RAT\|RGD=1307985\|UniProtKB=Q68FS4	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000005989\|UniProtKB=P00727	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000023604\|UniProtKB=P28839	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000018272.4\|UniProtKB=F7A676	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000026136.4\|UniProtKB=M3WRM3	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845000510.1\|UniProtKB=A0A8I3MBN3	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000000861.3\|UniProtKB=F7BHR0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000006661.4\|UniProtKB=F6XA92	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010010997.1\|UniProtKB=A0A8V0YG48	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011127.4\|UniProtKB=A0A803TTY4	Anolis carolinensis	LDO
XENLA\|Gene=lap3.L\|UniProtKB=A0A1L8HTP1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1006711\|UniProtKB=Q5XGB9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007934.2\|UniProtKB=H2LV22	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-060719-1\|UniProtKB=A2BIC6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003221.1\|UniProtKB=W5M605	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008012.3\|UniProtKB=F6SSX2	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_278441\|UniProtKB=C3YUJ8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC581093\|UniProtKB=A0A7M7NU31	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115924033\|UniProtKB=A0A7M7NTG4	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0035915\|UniProtKB=Q9VSM6	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0052351\|UniProtKB=Q9VSM7	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP001952\|UniProtKB=Q7PYI2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC004000\|UniProtKB=D6WIH3	Tribolium castaneum	O
DROME\|FlyBase=FBgn0259795\|UniProtKB=Q7K2S9	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0033868\|UniProtKB=Q500X4	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0034132\|UniProtKB=Q7K5K9	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0045770\|UniProtKB=Q961W5	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0052064\|UniProtKB=Q95R35	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0033860\|UniProtKB=A1Z9G3	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007904\|UniProtKB=A0A1S4GWM4	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC001175\|UniProtKB=D6WAL5	Tribolium castaneum	O
ANOGA\|EnsemblGenome=AGAP003869\|UniProtKB=Q7QFS4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC000378\|UniProtKB=D6WAL0	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_260731\|UniProtKB=E9HJS0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW019719\|UniProtKB=B7PRX1	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG117043\|UniProtKB=T1EGJ6	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g247890\|UniProtKB=A7SX56	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG32578\|UniProtKB=B3SB51	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_37195\|UniProtKB=A9V068	Monosiga brevicollis	LDO
SCHPO\|PomBase=SPAC13A11.05\|UniProtKB=Q09735	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03744\|UniProtKB=B6K2U4	Schizosaccharomyces japonicus	LDO
USTMA\|EnsemblGenome=UMAG_03308\|UniProtKB=A0A0D1E2A5	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_22457\|UniProtKB=H6QUM2	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_36951\|UniProtKB=F4P386	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0279793\|UniProtKB=Q5V9F0	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_91370\|UniProtKB=F0ZB91	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_23_0950\|UniProtKB=Q7KF27	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.8.3060\|UniProtKB=Q57W67	Trypanosoma brucei	LDO
PLAF7\|EnsemblGenome=PF3D7_1446200\|UniProtKB=Q8IL11	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00035011001\|UniProtKB=A0C414	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00032228001\|UniProtKB=A0BTX9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00034808001\|UniProtKB=A0C3G2	Paramecium tetraurelia	LDO
NITMS\|EnsemblGenome=Nmar_0296\|UniProtKB=A9A408	Nitrosopumilus maritimus	LDO
CHLAA\|EnsemblGenome=Caur_3339\|UniProtKB=A9WJQ9	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO2179\|UniProtKB=Q9S2Q7	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv2213\|UniProtKB=P9WHT3	Mycobacterium tuberculosis	LDO
MYCGE\|EnsemblGenome=MG_391\|UniProtKB=P47631	mycoplasma genitalium	LDO
STAA8\|EnsemblGenome=SAOUHSC_00879\|UniProtKB=Q2FZV6	Staphylococcus aureus	LDO
BACSU\|EnsemblGenome=BSU_32050\|UniProtKB=O32106	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_4921\|UniProtKB=Q816E3	Bacillus cereus	LDO
DEIRA\|EnsemblGenome=DR_0717\|UniProtKB=Q9RWF2	Deinococcus radiodurans	LDO
LEPIN\|EnsemblGenome=LA_3441\|UniProtKB=Q8F0Q1	Leptospira interrogans	LDO
CHLTR\|EnsemblGenome=CT_045\|UniProtKB=O84049	Chlamydia trachomatis	LDO
RHOBA\|EnsemblGenome=RB12107\|UniProtKB=Q7UJ62	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_2099\|UniProtKB=O67868	Aquifex aeolicus	LDO
FUSNN\|EnsemblGenome=FN1906\|UniProtKB=Q8RHT8	Fusobacterium nucleatum	LDO
HELPY\|EnsemblGenome=HP_0570\|UniProtKB=O25294	Helicobacter pylori	LDO
GEOSL\|EnsemblGenome=GSU0332\|UniProtKB=Q74GB4	Geobacter sulfurreducens	LDO
BRADU\|EnsemblGenome=BAC49373\|UniProtKB=Q89MT4	Bradyrhizobium diazoefficiens	LDO
HAEIN\|EnsemblGenome=HI_1705\|UniProtKB=P45334	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_0959\|UniProtKB=Q8EI85	Shewanella oneidensis	O
SHEON\|Gene_OrderedLocusName=SO_1368\|UniProtKB=Q8EH62	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_2501\|UniProtKB=P0C6E1	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC0649\|UniProtKB=Q8PCR4	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA3831\|UniProtKB=O68822	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM4477\|UniProtKB=Q8ZK29	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_0643\|UniProtKB=Q8ZBH3	Yersinia pestis	LDO