PANTHER Gene Information

Gene Symbol(s):

LAP

Organism:

Plasmodium falciparum

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Tree

Gene Name:

Leucine aminopeptidase

Gene ID:

PF3D7_1446200

Protein ID:

Q8IL11

Persistent Id:

PTN000943982

Alternate Ids:

PF3D7_1446200(Ensembl)	347948675(GI)
3.4.11.1 {ECO:0000269\|PubMed:17107951, ECO:0000269\|PubMed:19408962, ECO:0000269\|PubMed:21844374, ECO:0000269\|PubMed:22359643, ECO:0000269\|PubMed:33303633, ECO:0000269\|PubMed:33536500, ECO:0000269\|PubMed:34133730}(EC)	LN999946(EMBL)
CZU00157(Ensembl_TRS)	CZU00157(EMBL-CDS)
AMPL(Synonym)	LAP{ECO:0000303\|PubMed:17107951}(Symbol)
XM_001348577(refSeq)	CHEMBL1293313(ChEMBL)
812021(GeneID)	CZU00157(Ensembl_PRO)
AMPL_PLAF7(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	LEUCINE AMINOPEPTIDASE-RELATED (PTHR11963)
PANTHER Subfamily:	CYTOSOL AMINOPEPTIDASE (PTHR11963:SF23)
PANTHER GO-slim Molecular Function:	peptidase activity
PANTHER GO-slim Biological Process:	proteolysis
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	metalloprotease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	metal ion binding, metalloaminopeptidase activity, aminopeptidase activity, peptidase activity
GO BP Complete:	proteolysis
GO CC Complete:	cytoplasm, food vacuole, cytosol, apicoplast

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000050938.1\|UniProtKB=A0A2I3RAG2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000025194.2\|UniProtKB=A0A2I2YLC7	Gorilla gorilla gorilla	O
HUMAN\|HGNC=18449\|UniProtKB=P28838	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000015938.3\|UniProtKB=G2HHE6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000001110.4\|UniProtKB=G3QFL8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000005732.4\|UniProtKB=F6TQJ2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1914238\|UniProtKB=Q9CPY7	Mus musculus	LDO
RAT\|RGD=150343158\|UniProtKB=A0A8I6B0E2	Rattus norvegicus	O
RAT\|RGD=1307985\|UniProtKB=Q68FS4	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000005989\|UniProtKB=P00727	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000023604\|UniProtKB=P28839	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000018272.4\|UniProtKB=F7A676	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000026136.4\|UniProtKB=M3WRM3	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845000510.1\|UniProtKB=A0A8I3MBN3	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000000861.3\|UniProtKB=F7BHR0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000006661.4\|UniProtKB=F6XA92	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010010997.1\|UniProtKB=A0A8V0YG48	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011127.4\|UniProtKB=A0A803TTY4	Anolis carolinensis	LDO
XENLA\|Gene=lap3.L\|UniProtKB=A0A1L8HTP1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1006711\|UniProtKB=Q5XGB9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007934.2\|UniProtKB=H2LV22	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-060719-1\|UniProtKB=A2BIC6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003221.1\|UniProtKB=W5M605	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008012.3\|UniProtKB=F6SSX2	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_278441\|UniProtKB=C3YUJ8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC581093\|UniProtKB=A0A7M7NU31	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115924033\|UniProtKB=A0A7M7NTG4	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0035915\|UniProtKB=Q9VSM6	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0052351\|UniProtKB=Q9VSM7	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP001952\|UniProtKB=Q7PYI2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC004000\|UniProtKB=D6WIH3	Tribolium castaneum	O
DROME\|FlyBase=FBgn0259795\|UniProtKB=Q7K2S9	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0033868\|UniProtKB=Q500X4	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0034132\|UniProtKB=Q7K5K9	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0045770\|UniProtKB=Q961W5	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0052064\|UniProtKB=Q95R35	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0033860\|UniProtKB=A1Z9G3	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007904\|UniProtKB=A0A1S4GWM4	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC001175\|UniProtKB=D6WAL5	Tribolium castaneum	O
ANOGA\|EnsemblGenome=AGAP003869\|UniProtKB=Q7QFS4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC000378\|UniProtKB=D6WAL0	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_260731\|UniProtKB=E9HJS0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW019719\|UniProtKB=B7PRX1	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG117043\|UniProtKB=T1EGJ6	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g247890\|UniProtKB=A7SX56	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG32578\|UniProtKB=B3SB51	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_37195\|UniProtKB=A9V068	Monosiga brevicollis	LDO
SCHPO\|PomBase=SPAC13A11.05\|UniProtKB=Q09735	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03744\|UniProtKB=B6K2U4	Schizosaccharomyces japonicus	LDO
USTMA\|EnsemblGenome=UMAG_03308\|UniProtKB=A0A0D1E2A5	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_22457\|UniProtKB=H6QUM2	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_36951\|UniProtKB=F4P386	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0279793\|UniProtKB=Q5V9F0	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_91370\|UniProtKB=F0ZB91	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_23_0950\|UniProtKB=Q7KF27	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.8.3060\|UniProtKB=Q57W67	Trypanosoma brucei	LDO
PARTE\|EnsemblGenome=GSPATT00035011001\|UniProtKB=A0C414	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00032228001\|UniProtKB=A0BTX9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00034808001\|UniProtKB=A0C3G2	Paramecium tetraurelia	LDO
NITMS\|EnsemblGenome=Nmar_0296\|UniProtKB=A9A408	Nitrosopumilus maritimus	LDO
CHLAA\|EnsemblGenome=Caur_3339\|UniProtKB=A9WJQ9	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO2179\|UniProtKB=Q9S2Q7	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv2213\|UniProtKB=P9WHT3	Mycobacterium tuberculosis	LDO
MYCGE\|EnsemblGenome=MG_391\|UniProtKB=P47631	mycoplasma genitalium	LDO
STAA8\|EnsemblGenome=SAOUHSC_00879\|UniProtKB=Q2FZV6	Staphylococcus aureus	LDO
BACSU\|EnsemblGenome=BSU_32050\|UniProtKB=O32106	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_4921\|UniProtKB=Q816E3	Bacillus cereus	LDO
DEIRA\|EnsemblGenome=DR_0717\|UniProtKB=Q9RWF2	Deinococcus radiodurans	LDO
LEPIN\|EnsemblGenome=LA_3441\|UniProtKB=Q8F0Q1	Leptospira interrogans	LDO
CHLTR\|EnsemblGenome=CT_045\|UniProtKB=O84049	Chlamydia trachomatis	LDO
RHOBA\|EnsemblGenome=RB12107\|UniProtKB=Q7UJ62	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_2099\|UniProtKB=O67868	Aquifex aeolicus	LDO
FUSNN\|EnsemblGenome=FN1906\|UniProtKB=Q8RHT8	Fusobacterium nucleatum	LDO
BRADU\|Gene=Q89UI6_BRADU\|UniProtKB=Q89UI6	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_0572\|UniProtKB=Q83DX0	Coxiella burnetii	O
HAEIN\|Gene_OrderedLocusName=HI_0875\|UniProtKB=P58474	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_0876\|UniProtKB=Q8EIG3	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_0755\|UniProtKB=Q9KTX5	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC3904\|UniProtKB=Q8P412	Xanthomonas campestris	O
SALTY\|EnsemblGenome=STM2536\|UniProtKB=Q9RF52	Salmonella typhimurium	O
YERPE\|EnsemblGenome=YP_2566\|UniProtKB=P58475	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA16413\|UniProtKB=P37095	Escherichia coli	O
HELPY\|EnsemblGenome=HP_0570\|UniProtKB=O25294	Helicobacter pylori	LDO
GEOSL\|EnsemblGenome=GSU0332\|UniProtKB=Q74GB4	Geobacter sulfurreducens	LDO
BRADU\|EnsemblGenome=BAC49373\|UniProtKB=Q89MT4	Bradyrhizobium diazoefficiens	LDO
HAEIN\|EnsemblGenome=HI_1705\|UniProtKB=P45334	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_0959\|UniProtKB=Q8EI85	Shewanella oneidensis	O
SHEON\|Gene_OrderedLocusName=SO_1368\|UniProtKB=Q8EH62	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_2501\|UniProtKB=P0C6E1	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC0649\|UniProtKB=Q8PCR4	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA3831\|UniProtKB=O68822	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM4477\|UniProtKB=Q8ZK29	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_0643\|UniProtKB=Q8ZBH3	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAE78257\|UniProtKB=P68767	Escherichia coli	LDO