PANTHER Gene Information

Gene Symbol(s):

EHI_180450

Organism:

Entamoeba histolytica

View Gene in Tree

Tree

Gene Name:

Structural maintenance of chromosomes protein

Gene ID:

CL6EHI_180450

Protein ID:

C4M294

Persistent Id:

PTN000447983

Alternate Ids:

XP_653814(refSeq)	EHI_180450(Ensembl)
DS571221(EMBL)	67476422(GI)
C4M294(Synonym)	EAL48428(EMBL-CDS)
C4M294_ENTH1(UniProtKB-ID)	3408127(GeneID)
Show All

PANTHER Classification

PANTHER Family:	STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 (PTHR19306)
PANTHER Subfamily:	STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6 (PTHR19306:SF6)
PANTHER GO-slim Molecular Function:	single-stranded DNA binding damaged DNA binding
PANTHER GO-slim Biological Process:	double-strand break repair via homologous recombination
PANTHER GO-slim Cellular Component:	nucleus condensed chromosome site of double-strand break transferase complex
PANTHER protein class:	DNA metabolism protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP hydrolysis activity, ATP binding, damaged DNA binding, single-stranded DNA binding
GO BP Complete:	DNA repair, double-strand break repair via homologous recombination, DNA recombination, double-strand break repair
GO CC Complete:	nucleus, site of double-strand break, Smc5-Smc6 complex, chromosome

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=20466\|UniProtKB=Q96SB8	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000011677.5\|UniProtKB=A0A2I3SPZ8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000003864.3\|UniProtKB=G3QMQ4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000012056.4\|UniProtKB=A0A1D5Q104	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1914491\|UniProtKB=Q924W5	Mus musculus	LDO
RAT\|RGD=1311214\|UniProtKB=D4AB26	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000018256.6\|UniProtKB=E1BFH7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000008614.5\|UniProtKB=F1SCS4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022265.3\|UniProtKB=A0A9L0SAH8	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000013578.6\|UniProtKB=M3WJ36	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845016537.1\|UniProtKB=A0A8I3NQ06	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000046425.1\|UniProtKB=A0A5F8GK95	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000007190.3\|UniProtKB=F6X9P7	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000022800.3\|UniProtKB=H9H951	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000044713.1\|UniProtKB=A0A5F8HC33	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000011693.4\|UniProtKB=H9H6I4	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000003893.4\|UniProtKB=F7D883	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000010714.4\|UniProtKB=A0A6I8NJ74	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010002372.1\|UniProtKB=E1BWW3	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000001613.4\|UniProtKB=G1K9S9	Anolis carolinensis	LDO
XENLA\|Gene=LOC108717191\|UniProtKB=A0A8J1KRW1	Xenopus laevis	O
XENLA\|Gene=smc6\|UniProtKB=Q6P9I7	Xenopus laevis	LDO
XENTR\|Ensembl=ENSXETG00000044652\|UniProtKB=A0A6I8SJJ1	Xenopus tropicalis	O
XENTR\|Gene=LOC100496941\|UniProtKB=A0A8J0STX2	Xenopus tropicalis	O
XENTR\|Gene=smc6.1\|UniProtKB=A0A8J0R3G1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000018430.2\|UniProtKB=H2MW46	Oryzias latipes	O
DANRE\|Gene=smc6\|UniProtKB=A0A8M9PV42	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000013905.2\|UniProtKB=H2MFQ8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-070705-287\|UniProtKB=A0A8M1NHD0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000017236.1\|UniProtKB=W5NL09	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000021570.1\|UniProtKB=H2XL64	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118409497\|UniProtKB=A0A9J7HX12	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC100893240\|UniProtKB=A0A7M7N7J3	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC100893394\|UniProtKB=A0A7M7NLS3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC584232\|UniProtKB=A0A7M7HGZ6	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00007694\|UniProtKB=Q93250	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00010056\|UniProtKB=G5EG17	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00025824\|UniProtKB=A8WTD4	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00278280\|UniProtKB=A0A2A6CIJ4	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0266282\|UniProtKB=Q9VCB8	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002985\|UniProtKB=F7IWF2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC005764\|UniProtKB=D6WWE4	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_224715\|UniProtKB=E9GJ94	Daphnia pulex	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_103378\|UniProtKB=E9GJ61	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW014877\|UniProtKB=B7QGR1	Ixodes scapularis	LDO
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g113902\|UniProtKB=A7SD29	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG61013\|UniProtKB=B3S9S7	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_22018\|UniProtKB=A9UPA8	Monosiga brevicollis	LDO
YEAST\|SGD=S000004375\|UniProtKB=Q12749	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AER044W\|UniProtKB=Q757G9	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000185544\|UniProtKB=Q5AGX1	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F02365g\|UniProtKB=Q6C360	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_10415\|UniProtKB=C8VHA6	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_3G05440\|UniProtKB=Q4WWD4	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU02402\|UniProtKB=Q7S4N3	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_14153\|UniProtKB=A7F972	Sclerotinia sclerotiorum	O
SCLS1\|EnsemblGenome=SS1G_11001\|UniProtKB=A7F084	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_14536\|UniProtKB=Q0U125	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCC5E4.06\|UniProtKB=P53692	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02545\|UniProtKB=B6K0I9	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CND03960\|UniProtKB=Q5KI73	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_00739\|UniProtKB=A0A0D1CH81	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_19860\|UniProtKB=E3LBA0	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_34779\|UniProtKB=F4NZZ5	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0288993\|UniProtKB=Q54I56	Dictyostelium discoideum	LDO
GIAIC\|EnsemblGenome=GL50803_7648\|UniProtKB=A8BWV2	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_383600\|UniProtKB=A2EZ69	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_176480\|UniProtKB=A2FTH1	Trichomonas vaginalis	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_1743\|UniProtKB=B8BRT7	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GEM3_PHYRM\|UniProtKB=H3GEM3	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_12g525100v5\|UniProtKB=A0A2K3D4E3	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_12g525050v5\|UniProtKB=A0A2K3D4C5	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00106p00113730\|UniProtKB=W1NYM1	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_46G00270\|UniProtKB=A0A0K9P278	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma05_g13310\|UniProtKB=A0A804J3Z2	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_028787mg\|UniProtKB=K3ZQA7	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G154400\|UniProtKB=C5X880	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb309160\|UniProtKB=C0PG09	Zea mays	LDO
BRADI\|EnsemblGenome=BRADI_4g08527v3\|UniProtKB=A0A0Q3H0U2	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0468410\|UniProtKB=A0A8I6XNT2	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6B02G071100\|UniProtKB=A0A3B6PHU4	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G162400\|UniProtKB=A0A3B6KGQ8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G166500\|UniProtKB=A0A3B6MNL0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCSU02G112500\|UniProtKB=A0A3B6U639	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G159900\|UniProtKB=A0A3B6LKF8	Triticum aestivum	LDO
NELNU\|Gene=LOC104598515\|UniProtKB=A0A1U8AB63	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110782358\|UniProtKB=A0A9R0JPD2	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr01g0041251\|UniProtKB=A0A251VT92	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C900477820\|UniProtKB=A0A9R1WW23	Lactuca sativa	LDO
SOLLC\|EnsemblGenome=Solyc05g051680.3\|UniProtKB=A0A3Q7GL50	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107774285\|UniProtKB=A0A1S3YB74	Nicotiana tabacum	O
TOBAC\|Gene=LOC107786915\|UniProtKB=A0A1S3ZHK2	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi16g00299\|UniProtKB=D7U753	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_A02900\|UniProtKB=A0A059DKA6	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00078557001\|UniProtKB=A0A078FM81	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00071677001\|UniProtKB=A0A078HSQ9	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra028687\|UniProtKB=M4EIS2	Brassica campestris	LDO
ARATH\|TAIR=locus=2160289\|UniProtKB=Q9FLR5	Arabidopsis thaliana	LDO
BRANA\|Gene_ORFName=GSBRNA2T00020287001\|UniProtKB=A0A078J3M8	Brassica napus	O
BRACM\|EnsemblGenome=Bra012956\|UniProtKB=M4D8Z6	Brassica campestris	O
ARATH\|TAIR=locus=2161163\|UniProtKB=Q9FII7	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107933515\|UniProtKB=A0A1U8M6D4	Gossypium hirsutum	O
GOSHI\|Gene=LOC107955117\|UniProtKB=A0A1U8P7Q7	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_014905\|UniProtKB=A0A061G0D8	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_003G107700v3\|UniProtKB=A0A2K2B516	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_06G133600\|UniProtKB=A0A251L524	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1500700\|UniProtKB=B9R9U6	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_09G229900\|UniProtKB=I1L5P0	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g061050\|UniProtKB=G7JRH6	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_4g036760\|UniProtKB=A0A072UIF4	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr01_03090\|UniProtKB=A0A2I4GB24	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G022340\|UniProtKB=A0A0A0KXK2	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_2G275800\|UniProtKB=A0A251QMH6	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_60327\|UniProtKB=D8QR98	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_60332\|UniProtKB=D8RJK4	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c11_11190\|UniProtKB=A0A2K1JUB6	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0003s0057\|UniProtKB=A0A2R6XSR2	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_006080090\|UniProtKB=A0A1Y1IH23	Klebsormidium nitens	LDO