PANTHER Gene Information

Gene Symbol(s):

DDX11

Organism:

Felis catus

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Tree

Gene Name:

DEAD_H-box helicase 11

Gene ID:

ENSFCAG00000016277.6

Protein ID:

M3WNC5

Persistent Id:

PTN001690228

Alternate Ids:

M3WNC5(Synonym)	M3WNC5_FELCA(UniProtKB-ID)
1126435747(GI)	ENSFCAT00000016281(Ensembl_TRS)
101097815(GeneID)	ENSFCAP00000015131(Ensembl_PRO)
AANG04001873(EMBL)	ENSFCAG00000016277(Ensembl)
XM_019834353(refSeq)
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PANTHER Classification

PANTHER Family:	DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER (PTHR11472)
PANTHER Subfamily:	ATP-DEPENDENT DNA HELICASE DDX11-RELATED (PTHR11472:SF41)
PANTHER GO-slim Molecular Function:	DNA helicase activity
PANTHER GO-slim Biological Process:	DNA duplex unwinding sister chromatid cohesion
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	DNA helicase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP-dependent activity, acting on DNA, ATP-dependent activity, acting on RNA, double-stranded DNA binding, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, helicase activity, chromatin binding, single-stranded DNA binding, 5'-3' DNA helicase activity, DNA binding, DNA replication origin binding, ATP binding, DNA helicase activity, G-quadruplex DNA binding, metal ion binding, triplex DNA binding, single-stranded RNA binding, iron-sulfur cluster binding, hydrolase activity, isomerase activity
GO BP Complete:	sister chromatid cohesion, establishment of sister chromatid cohesion, cellular response to cisplatin, G-quadruplex DNA unwinding, cellular response to bleomycin, DNA damage response, nucleobase-containing compound metabolic process, positive regulation of sister chromatid cohesion, positive regulation of transcription of nucleolar large rRNA by RNA polymerase I, DNA duplex unwinding, nucleolar chromatin organization, cellular response to hydroxyurea, replication fork processing, positive regulation of double-strand break repair
GO CC Complete:	Ctf18 RFC-like complex, nucleus, centrosome, spindle pole, midbody, nucleolus, chromatin, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2737\|UniProtKB=Q92771	Homo sapiens	O
HUMAN\|HGNC=37101\|UniProtKB=A8MPP1	Homo sapiens	O
HUMAN\|HGNC=2736\|UniProtKB=Q96FC9	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000004804.7\|UniProtKB=A0A2I3S5T0	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015462.3\|UniProtKB=A0A2I2YA57	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000022864.4\|UniProtKB=F7GR78	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2443590\|UniProtKB=Q6AXC6	Mus musculus	LDO
RAT\|RGD=1306675\|UniProtKB=A0A0G2K8J3	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000007093.7\|UniProtKB=E1BL06	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000000745.5\|UniProtKB=F1SK84	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000010144.4\|UniProtKB=A0A5F5PWJ2	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845025631.1\|UniProtKB=A0A8I3PVX8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000018370.4\|UniProtKB=F6RFQ7	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010012138.1\|UniProtKB=A0A8V0YLC1	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000000039.4\|UniProtKB=A0A803TJC3	Anolis carolinensis	LDO
XENLA\|Gene=ddx11.L\|UniProtKB=A0A8J0UH99	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-969935\|UniProtKB=B5DEB4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000008936.2\|UniProtKB=H2LYJ0	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-041114-191\|UniProtKB=F1R345	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000016875.1\|UniProtKB=W5NJQ6	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006815.3\|UniProtKB=F6TZU9	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118419268\|UniProtKB=A0A9J7LEQ7	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC587249\|UniProtKB=A0A7M7NKM4	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00010839\|UniProtKB=Q21489	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00037830\|UniProtKB=A8XSL8	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00109405\|UniProtKB=A0A2A6BJ36	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0026876\|UniProtKB=Q9XZS9	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP001537\|UniProtKB=Q7PXR8	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC008173\|UniProtKB=D2A079	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_190335\|UniProtKB=E9FRG6	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG106032\|UniProtKB=T1EDZ3	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG25417\|UniProtKB=B3RYJ4	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_27452\|UniProtKB=A9V5B3	Monosiga brevicollis	LDO
YEAST\|SGD=S000005929\|UniProtKB=P22516	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AGL010W\|UniProtKB=Q750G3	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000177726\|UniProtKB=Q5AD67	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_C23639g\|UniProtKB=Q6CAX3	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_10414\|UniProtKB=C8VHC2	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_3G05590\|UniProtKB=Q4WWE9	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU11409\|UniProtKB=A7UXD4	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_07915\|UniProtKB=A7ERG1	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_15940\|UniProtKB=Q0TXC3	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC3G6.11\|UniProtKB=O14147	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_01644\|UniProtKB=B6JYI3	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNB05090\|UniProtKB=Q5KLJ0	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_10401\|UniProtKB=A0A0D1C4R5	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_00794\|UniProtKB=E3JTR2	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_11514\|UniProtKB=F4P382	Batrachochytrium dendrobatidis	LDO
LEIMA\|EnsemblGenome=LMJF_03_0590\|UniProtKB=E9ACK4	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.70.3870\|UniProtKB=Q38BP4	Trypanosoma brucei	LDO
TRIV3\|Gene_ORFName=TVAG_373000\|UniProtKB=A2DZG3	Trichomonas vaginalis	LDO
TRIV3\|Gene_ORFName=TVAG_390170\|UniProtKB=A2E1B9	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_288470\|UniProtKB=A2FEA7	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_1324500\|UniProtKB=Q8IE72	Plasmodium falciparum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_261639\|UniProtKB=B8BWV6	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G5M4_PHYRM\|UniProtKB=H3G5M4	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_07g322300v5\|UniProtKB=A0A2K3DJ45	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00109p00029010\|UniProtKB=W1NTN6	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_27G00820\|UniProtKB=A0A0K9PDH7	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_11G00810\|UniProtKB=A0A0K9Q189	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma06_g15580\|UniProtKB=A0A804JGL5	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_024123mg\|UniProtKB=K3ZC49	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3009G081800\|UniProtKB=A0A1B6P7B5	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb284740\|UniProtKB=A0A1D6M0P3	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os05g0219800\|UniProtKB=A0A0P0WJI0	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g31967v3\|UniProtKB=A0A0Q3R0R3	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0032230\|UniProtKB=A0A8I6WRF3	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1A02G419800\|UniProtKB=A0A3B5Y6U7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1A02G127600\|UniProtKB=A0A3B5XX68	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G126400\|UniProtKB=A0A3B5ZSR9	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS1B02G449800\|UniProtKB=A0A3B5Z607	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G427500\|UniProtKB=A0A3B6A234	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_028396\|UniProtKB=A0A1U7ZQD7	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110786618\|UniProtKB=A0A9R0ICP7	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0415481\|UniProtKB=A0A251U3C2	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C400197910\|UniProtKB=A0A9R1XIC2	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a022089mg\|UniProtKB=A0A022Q4U5	Erythranthe guttata	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a020316mg\|UniProtKB=A0A022Q0I1	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_17462\|UniProtKB=A0A2G2ZBM0	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400016505\|UniProtKB=M1BD85	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc06g066670.3\|UniProtKB=A0A3Q7GZL3	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107800491\|UniProtKB=A0A1S4ARN0	Nicotiana tabacum	O
TOBAC\|Gene=LOC107831480\|UniProtKB=A0A1S4DMT8	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi09g00371\|UniProtKB=F6HYE8	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_J02976\|UniProtKB=A0A059AIY2	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00030856001\|UniProtKB=A0A078F7M4	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00044097001\|UniProtKB=A0A078JBQ8	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra026607\|UniProtKB=M4ECU7	Brassica campestris	LDO
ARATH\|TAIR=locus=2017894\|UniProtKB=Q9CA92	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107897200\|UniProtKB=A0A1U8IIT9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107913908\|UniProtKB=A0A1U8K6D3	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_028743\|UniProtKB=A0A061GAA1	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g002378mg\|UniProtKB=A0A067F106	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_001G182600v3\|UniProtKB=B9GG23	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_11G044500\|UniProtKB=A0A2C9UZL5	Manihot esculenta	LDO
SOYBN\|EnsemblGenome=GLYMA_07G005000\|UniProtKB=I1KG67	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_0147s0060\|UniProtKB=A0A072TSN1	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr07_30030\|UniProtKB=A0A2I4G0S0	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_7G446880\|UniProtKB=A0A0A0K7C4	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_3G069100\|UniProtKB=M5XDT6	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_132642\|UniProtKB=D8T5X7	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_116951\|UniProtKB=D8SHM3	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c9_5880\|UniProtKB=A0A2K1K275	Physcomitrella patens	LDO
KLENI\|Gene_ORFName=KFL_004240080\|UniProtKB=A0A1Y1II53	Klebsormidium nitens	LDO
KORCO\|EnsemblGenome=Kcr_1439\|UniProtKB=B1L6V6	Korarchaeum cryptofilum	O
KORCO\|EnsemblGenome=Kcr_1088\|UniProtKB=B1L5V5	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO0313\|UniProtKB=Q980I2	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE3526\|UniProtKB=Q8ZSY2	Pyrobaculum aerophilum	O
PYRAE\|EnsemblGenome=PAE2991\|UniProtKB=Q8ZU14	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_2096\|UniProtKB=Q8TP28	Methanosarcina acetivorans	O
METAC\|EnsemblGenome=MA_0335\|UniProtKB=Q8TTU0	Methanosarcina acetivorans	O
METJA\|EnsemblGenome=MJ_0942\|UniProtKB=Q58352	Methanocaldococcus jannaschii	O
HALSA\|EnsemblGenome=VNG_1383G\|UniProtKB=Q9HQ08	Halobacterium salinarum	O
HALSA\|EnsemblGenome=VNG_2476C\|UniProtKB=Q9HMM1	Halobacterium salinarum	O
HALSA\|EnsemblGenome=VNG_2441G\|UniProtKB=Q9HMP9	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK0784\|UniProtKB=Q5JH96	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_1621\|UniProtKB=A9WBN2	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO5802\|UniProtKB=O69978	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv1329c\|UniProtKB=P9WMR5	Mycobacterium tuberculosis	O
LISMO\|Gene=dinG\|UniProtKB=Q8Y604	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_22150\|UniProtKB=P50831	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_1565\|UniProtKB=Q81FL6	Bacillus cereus	O
BACSU\|EnsemblGenome=BSU_22400\|UniProtKB=P54394	Bacillus subtilis	O
GLOVI\|Gene=Q7NKM8_GLOVI\|UniProtKB=Q7NKM8	Gloeobacter violaceus	O
SYNY3\|Gene=P72618_SYNY3\|UniProtKB=P72618	Synechocystis	O
GLOVI\|Gene=Q7NN01_GLOVI\|UniProtKB=Q7NN01	Gloeobacter violaceus	O
LEPIN\|EnsemblGenome=LA_1875\|UniProtKB=Q8F513	Leptospira interrogans	O
RHOBA\|EnsemblGenome=RB8062\|UniProtKB=Q7UG83	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_358\|UniProtKB=O66684	Aquifex aeolicus	O
FUSNN\|EnsemblGenome=FN0743\|UniProtKB=Q8RFF8	Fusobacterium nucleatum	O
NEIMB\|EnsemblGenome=NMB0287\|UniProtKB=Q9K181	Neisseria meningitidis serogroup b	O
SHEON\|Gene_OrderedLocusName=SO_1819\|UniProtKB=Q8EFZ5	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_1855\|UniProtKB=Q9KQZ2	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC3950\|UniProtKB=Q8P3W9	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA1045\|UniProtKB=Q9I4S9	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM0821\|UniProtKB=Q8ZQN7	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO1206\|UniProtKB=A0A2S9PKW4	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA35465\|UniProtKB=P27296	Escherichia coli	O
GEOSL\|EnsemblGenome=GSU0363\|UniProtKB=Q74G84	Geobacter sulfurreducens	O
HAEIN\|EnsemblGenome=HI_0387\|UniProtKB=P44680	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_2081\|UniProtKB=Q8EFA4	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_1990\|UniProtKB=Q9KQK8	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC2930\|UniProtKB=Q8P6N7	Xanthomonas campestris	O
SALTY\|EnsemblGenome=STM1821\|UniProtKB=Q7CQD9	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO2071\|UniProtKB=A0A3N4B3X5	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA15617\|UniProtKB=P76257	Escherichia coli	O