PANTHER Gene Information

Gene Symbol(s):

DDX12P

Organism:

Homo sapiens

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Gene Name:

Putative ATP-dependent RNA helicase DDX12

Gene ID:

HGNC:2737

Protein ID:

Q92771

Enhancers:

View enhancers for HUMAN|HGNC=2737|UniProtKB=Q92771

Genetic Variant Annotation:

Annoq

Persistent Id:

PTN002479321

Alternate Ids:

182705254(GI)	3.6.4.13(EC)
HGNC:2737(HGNC)	hCHLR2(Synonym)
AC141557(EMBL)	DDX12_HUMAN(UniProtKB-ID)
DDX12P(Symbol)	601151(MIM)
AAB06963(EMBL-CDS)
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PANTHER Classification

PANTHER Family:	DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER (PTHR11472)
PANTHER Subfamily:	ATP-DEPENDENT DNA HELICASE DDX11-RELATED (PTHR11472:SF41)
PANTHER GO-slim Molecular Function:	DNA helicase activity
PANTHER GO-slim Biological Process:	DNA duplex unwinding sister chromatid cohesion
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	DNA helicase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, ATP binding, DNA helicase activity, RNA binding, RNA helicase activity, metal ion binding, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, iron-sulfur cluster binding, isomerase activity
GO BP Complete:	establishment of sister chromatid cohesion, DNA duplex unwinding, nucleobase-containing compound metabolic process
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000004804.7\|UniProtKB=A0A2I3S5T0	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000015462.3\|UniProtKB=A0A2I2YA57	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000022864.4\|UniProtKB=F7GR78	Macaca mulatta	O
MOUSE\|MGI=MGI=2443590\|UniProtKB=Q6AXC6	Mus musculus	O
RAT\|RGD=1306675\|UniProtKB=A0A0G2K8J3	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000007093.7\|UniProtKB=E1BL06	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000000745.5\|UniProtKB=F1SK84	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000010144.4\|UniProtKB=A0A5F5PWJ2	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000016277.6\|UniProtKB=M3WNC5	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845025631.1\|UniProtKB=A0A8I3PVX8	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000018370.4\|UniProtKB=F6RFQ7	Monodelphis domestica	O
CHICK\|Ensembl=ENSGALG00010012138.1\|UniProtKB=A0A8V0YLC1	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000000039.4\|UniProtKB=A0A803TJC3	Anolis carolinensis	O
XENLA\|Gene=ddx11.L\|UniProtKB=A0A8J0UH99	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-969935\|UniProtKB=B5DEB4	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000008936.2\|UniProtKB=H2LYJ0	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-041114-191\|UniProtKB=F1R345	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000016875.1\|UniProtKB=W5NJQ6	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000006815.3\|UniProtKB=F6TZU9	Ciona intestinalis	O
BRAFL\|Gene=LOC118419268\|UniProtKB=A0A9J7LEQ7	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC587249\|UniProtKB=A0A7M7NKM4	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00010839\|UniProtKB=Q21489	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00037830\|UniProtKB=A8XSL8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00109405\|UniProtKB=A0A2A6BJ36	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0026876\|UniProtKB=Q9XZS9	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP001537\|UniProtKB=Q7PXR8	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC008173\|UniProtKB=D2A079	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_190335\|UniProtKB=E9FRG6	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG106032\|UniProtKB=T1EDZ3	helobdella robusta	O
TRIAD\|EnsemblGenome=TriadG25417\|UniProtKB=B3RYJ4	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_27452\|UniProtKB=A9V5B3	Monosiga brevicollis	O
YEAST\|SGD=S000005929\|UniProtKB=P22516	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AGL010W\|UniProtKB=Q750G3	Eremothecium gossypii	O
CANAL\|CGD=CAL0000177726\|UniProtKB=Q5AD67	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_C23639g\|UniProtKB=Q6CAX3	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_10414\|UniProtKB=C8VHC2	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G05590\|UniProtKB=Q4WWE9	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU11409\|UniProtKB=A7UXD4	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_07915\|UniProtKB=A7ERG1	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_15940\|UniProtKB=Q0TXC3	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC3G6.11\|UniProtKB=O14147	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_01644\|UniProtKB=B6JYI3	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNB05090\|UniProtKB=Q5KLJ0	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_10401\|UniProtKB=A0A0D1C4R5	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_00794\|UniProtKB=E3JTR2	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_11514\|UniProtKB=F4P382	Batrachochytrium dendrobatidis	O
LEIMA\|EnsemblGenome=LMJF_03_0590\|UniProtKB=E9ACK4	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.70.3870\|UniProtKB=Q38BP4	Trypanosoma brucei	O
TRIV3\|Gene_ORFName=TVAG_373000\|UniProtKB=A2DZG3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_390170\|UniProtKB=A2E1B9	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_288470\|UniProtKB=A2FEA7	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_1324500\|UniProtKB=Q8IE72	Plasmodium falciparum	O
THAPS\|EnsemblGenome=THAPSDRAFT_261639\|UniProtKB=B8BWV6	Thalassiosira pseudonana	O
PHYRM\|Gene=H3G5M4_PHYRM\|UniProtKB=H3G5M4	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_07g322300v5\|UniProtKB=A0A2K3DJ45	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00109p00029010\|UniProtKB=W1NTN6	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_27G00820\|UniProtKB=A0A0K9PDH7	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_11G00810\|UniProtKB=A0A0K9Q189	Zostera marina	O
MUSAM\|EnsemblGenome=Ma06_g15580\|UniProtKB=A0A804JGL5	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_024123mg\|UniProtKB=K3ZC49	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3009G081800\|UniProtKB=A0A1B6P7B5	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb284740\|UniProtKB=A0A1D6M0P3	Zea mays	O
ORYSJ\|EnsemblGenome=Os05g0219800\|UniProtKB=A0A0P0WJI0	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_2g31967v3\|UniProtKB=A0A0Q3R0R3	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0032230\|UniProtKB=A0A8I6WRF3	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS1A02G419800\|UniProtKB=A0A3B5Y6U7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1A02G127600\|UniProtKB=A0A3B5XX68	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G126400\|UniProtKB=A0A3B5ZSR9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1B02G449800\|UniProtKB=A0A3B5Z607	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G427500\|UniProtKB=A0A3B6A234	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_028396\|UniProtKB=A0A1U7ZQD7	Nelumbo nucifera	O
SPIOL\|Gene=LOC110786618\|UniProtKB=A0A9R0ICP7	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0415481\|UniProtKB=A0A251U3C2	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C400197910\|UniProtKB=A0A9R1XIC2	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a022089mg\|UniProtKB=A0A022Q4U5	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a020316mg\|UniProtKB=A0A022Q0I1	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_17462\|UniProtKB=A0A2G2ZBM0	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400016505\|UniProtKB=M1BD85	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc06g066670.3\|UniProtKB=A0A3Q7GZL3	Solanum lycopersicum	O
TOBAC\|Gene=LOC107800491\|UniProtKB=A0A1S4ARN0	Nicotiana tabacum	O
TOBAC\|Gene=LOC107831480\|UniProtKB=A0A1S4DMT8	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi09g00371\|UniProtKB=F6HYE8	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_J02976\|UniProtKB=A0A059AIY2	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00030856001\|UniProtKB=A0A078F7M4	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00044097001\|UniProtKB=A0A078JBQ8	Brassica napus	O
BRACM\|EnsemblGenome=Bra026607\|UniProtKB=M4ECU7	Brassica campestris	O
ARATH\|TAIR=locus=2017894\|UniProtKB=Q9CA92	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107897200\|UniProtKB=A0A1U8IIT9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107913908\|UniProtKB=A0A1U8K6D3	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_028743\|UniProtKB=A0A061GAA1	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g002378mg\|UniProtKB=A0A067F106	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_001G182600v3\|UniProtKB=B9GG23	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_11G044500\|UniProtKB=A0A2C9UZL5	Manihot esculenta	O
SOYBN\|EnsemblGenome=GLYMA_07G005000\|UniProtKB=I1KG67	Glycine max	O
MEDTR\|EnsemblGenome=MTR_0147s0060\|UniProtKB=A0A072TSN1	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr07_30030\|UniProtKB=A0A2I4G0S0	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_7G446880\|UniProtKB=A0A0A0K7C4	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_3G069100\|UniProtKB=M5XDT6	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_132642\|UniProtKB=D8T5X7	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_116951\|UniProtKB=D8SHM3	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c9_5880\|UniProtKB=A0A2K1K275	Physcomitrella patens	O
KLENI\|Gene_ORFName=KFL_004240080\|UniProtKB=A0A1Y1II53	Klebsormidium nitens	O
KORCO\|EnsemblGenome=Kcr_1439\|UniProtKB=B1L6V6	Korarchaeum cryptofilum	O
KORCO\|EnsemblGenome=Kcr_1088\|UniProtKB=B1L5V5	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO0313\|UniProtKB=Q980I2	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE3526\|UniProtKB=Q8ZSY2	Pyrobaculum aerophilum	O
PYRAE\|EnsemblGenome=PAE2991\|UniProtKB=Q8ZU14	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_2096\|UniProtKB=Q8TP28	Methanosarcina acetivorans	O
METAC\|EnsemblGenome=MA_0335\|UniProtKB=Q8TTU0	Methanosarcina acetivorans	O
METJA\|EnsemblGenome=MJ_0942\|UniProtKB=Q58352	Methanocaldococcus jannaschii	O
HALSA\|EnsemblGenome=VNG_1383G\|UniProtKB=Q9HQ08	Halobacterium salinarum	O
HALSA\|EnsemblGenome=VNG_2476C\|UniProtKB=Q9HMM1	Halobacterium salinarum	O
HALSA\|EnsemblGenome=VNG_2441G\|UniProtKB=Q9HMP9	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK0784\|UniProtKB=Q5JH96	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_1621\|UniProtKB=A9WBN2	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO5802\|UniProtKB=O69978	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv1329c\|UniProtKB=P9WMR5	Mycobacterium tuberculosis	O
LISMO\|Gene=dinG\|UniProtKB=Q8Y604	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_22150\|UniProtKB=P50831	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_1565\|UniProtKB=Q81FL6	Bacillus cereus	O
BACSU\|EnsemblGenome=BSU_22400\|UniProtKB=P54394	Bacillus subtilis	O
GLOVI\|Gene=Q7NKM8_GLOVI\|UniProtKB=Q7NKM8	Gloeobacter violaceus	O
SYNY3\|Gene=P72618_SYNY3\|UniProtKB=P72618	Synechocystis	O
GLOVI\|Gene=Q7NN01_GLOVI\|UniProtKB=Q7NN01	Gloeobacter violaceus	O
LEPIN\|EnsemblGenome=LA_1875\|UniProtKB=Q8F513	Leptospira interrogans	O
RHOBA\|EnsemblGenome=RB8062\|UniProtKB=Q7UG83	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_358\|UniProtKB=O66684	Aquifex aeolicus	O
FUSNN\|EnsemblGenome=FN0743\|UniProtKB=Q8RFF8	Fusobacterium nucleatum	O
NEIMB\|EnsemblGenome=NMB0287\|UniProtKB=Q9K181	Neisseria meningitidis serogroup b	O
SHEON\|Gene_OrderedLocusName=SO_1819\|UniProtKB=Q8EFZ5	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_1855\|UniProtKB=Q9KQZ2	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC3950\|UniProtKB=Q8P3W9	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA1045\|UniProtKB=Q9I4S9	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM0821\|UniProtKB=Q8ZQN7	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO1206\|UniProtKB=A0A2S9PKW4	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA35465\|UniProtKB=P27296	Escherichia coli	O
GEOSL\|EnsemblGenome=GSU0363\|UniProtKB=Q74G84	Geobacter sulfurreducens	O
HAEIN\|EnsemblGenome=HI_0387\|UniProtKB=P44680	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_2081\|UniProtKB=Q8EFA4	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_1990\|UniProtKB=Q9KQK8	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC2930\|UniProtKB=Q8P6N7	Xanthomonas campestris	O
SALTY\|EnsemblGenome=STM1821\|UniProtKB=Q7CQD9	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO2071\|UniProtKB=A0A3N4B3X5	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA15617\|UniProtKB=P76257	Escherichia coli	O