PANTHER Gene Information

Gene Symbol(s):

LRP1

Organism:

Gorilla gorilla gorilla

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Gene Name:

LDL receptor related protein 1

Gene ID:

ENSGGOG00000010171.3

Protein ID:

G3R3Z1

Persistent Id:

PTN002778404

Alternate Ids:

CABD030083536(EMBL)	ENSGGOG00000010171(Ensembl)
ENSGGOT00000010264(Ensembl_TRS)	G3R3Z1(Synonym)
ENSGGOP00000009976(Ensembl_PRO)	G3R3Z1_GORGO(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED (PTHR46513)
PANTHER Subfamily:	LDL RECEPTOR RELATED PROTEIN 1-RELATED (PTHR46513:SF37)
PANTHER GO-slim Molecular Function:	transmembrane signaling receptor activity Wnt-protein binding
PANTHER GO-slim Biological Process:	canonical Wnt signaling pathway
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	transmembrane signal receptor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	alpha-2 macroglobulin receptor activity, clathrin heavy chain binding, apolipoprotein binding, calcium ion binding, cargo receptor activity, protein-containing complex binding
GO BP Complete:	positive regulation of lysosomal protein catabolic process, positive regulation of endocytosis, amyloid-beta clearance by transcytosis, positive regulation of protein localization to plasma membrane, amyloid-beta clearance by cellular catabolic process, phagocytosis, endocytosis, receptor-mediated endocytosis
GO CC Complete:	early endosome, membrane, receptor complex, basolateral plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
CHICK\|Ensembl=ENSGALG00010025368.1\|UniProtKB=A0A8V1AA50	Gallus gallus	LDO
CHICK\|Gene=LRP1\|UniProtKB=P98157	Gallus gallus	LDO
ORYLA\|Ensembl=ENSORLG00000029487.1\|UniProtKB=A0A3B3IEL5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000025636.1\|UniProtKB=A0A3B3I0H7	Oryzias latipes	LDO
ORYLA\|Ensembl=ENSORLG00000023990.1\|UniProtKB=A0A3B3HXJ5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000030474.1\|UniProtKB=A0A3B3I0G6	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000006089.1\|UniProtKB=W5MG75	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000017654.2\|UniProtKB=F6WZ22	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000022078.1\|UniProtKB=H2XLM3	Ciona intestinalis	O
BRAFL\|Gene=LOC118427149\|UniProtKB=A0A9J7M3Y3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427146\|UniProtKB=A0A9J7M151	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409884\|UniProtKB=A0A9J7KNA2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427150\|UniProtKB=A0A9J7M0V8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418087\|UniProtKB=A0A9J7LDW4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418084\|UniProtKB=A0A9J7MUW8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427152\|UniProtKB=A0A9J7M0S3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417668\|UniProtKB=A0A9J7MUH3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405902\|UniProtKB=A0A9J7KGA4	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC581905\|UniProtKB=A0A7M7P5D6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105438789\|UniProtKB=A0A7M7PMS8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115923116\|UniProtKB=A0A7M7NNP7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100888447\|UniProtKB=A0A7M7NE90	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446596\|UniProtKB=A0A7M7NG87	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115929295\|UniProtKB=A0A7M7T4T3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC586685\|UniProtKB=A0A7M7RDE0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC594262\|UniProtKB=A0A7M7PLJ1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115925099\|UniProtKB=A0A7M7NZZ2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446106\|UniProtKB=A0A7M7PI37	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105443672\|UniProtKB=A0A7M7HKG7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115924457\|UniProtKB=A0A7M7NVQ1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC591940\|UniProtKB=A0A7M7NLH8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC754161\|UniProtKB=A0A7M7SXU5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446184\|UniProtKB=A0A7M7PJR2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC757083\|UniProtKB=A0A7M7PKJ0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105442855\|UniProtKB=A0A7M7NNI7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115924993\|UniProtKB=A0A7M7NZA2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115923115\|UniProtKB=A0A7M7NND0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105442169\|UniProtKB=A0A7M7NRG6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115923430\|UniProtKB=A0A7M7NQ26	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115926091\|UniProtKB=A0A7M7P7Q5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC587773\|UniProtKB=A0A7M7NGF7	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00004374\|UniProtKB=O44191	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG03794\|UniProtKB=A8WWR1	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00109458\|UniProtKB=A0A2A6BAV3	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00008779\|UniProtKB=G5EFK8	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG09505\|UniProtKB=A8X8Y5	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00038687\|UniProtKB=A8XVN1	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00100282\|UniProtKB=A0A2A6BMJ2	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0011204\|UniProtKB=Q95RU0	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007023\|UniProtKB=Q7QIQ6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC002911\|UniProtKB=D6WHF9	Tribolium castaneum	O
ANOGA\|EnsemblGenome=AGAP008193\|UniProtKB=A0A1S4GXK2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC031834\|UniProtKB=A0A139WA84	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_237349\|UniProtKB=E9G3P6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_314322\|UniProtKB=E9G6S4	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_248813\|UniProtKB=E9GVA3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_303927\|UniProtKB=E9GIG6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_313913\|UniProtKB=E9G5N7	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_303856\|UniProtKB=E9GIF7	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_303858\|UniProtKB=E9GIF9	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_318319\|UniProtKB=E9GIG3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_263601\|UniProtKB=E9HQ28	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_318320\|UniProtKB=E9GIG4	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_303924\|UniProtKB=E9GIG2	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_68539\|UniProtKB=E9I293	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG180677\|UniProtKB=T1FG57	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG178815\|UniProtKB=T1FDS3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG188530\|UniProtKB=T1FQ35	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG170722\|UniProtKB=T1F3D0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG175287\|UniProtKB=T1F941	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG164869\|UniProtKB=T1EVW5	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG185306\|UniProtKB=T1FMN1	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g118240\|UniProtKB=A7SH94	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g177505\|UniProtKB=A7RGB1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g83852\|UniProtKB=A7RJD6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g212268\|UniProtKB=A7SH97	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g245263\|UniProtKB=A7SH96	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g61732\|UniProtKB=A7RIK9	Nematostella vectensis	O