PANTHER Gene Information   
Gene Symbol(s): rme-2
Organism: Caenorhabditis elegans
View Gene in Tree
Tree Reduced Tree  
Tree Reduced Tree
Gene Name: EGF-like domain-containing protein
Gene ID: WBGene00004374
Protein ID: O44191
Persistent Id: PTN000056039
Alternate Ids:
WBGene00004374(WormBase) CE22368(WormBase_PRO)
O44191_CAEEL(UniProtKB-ID) 177329(GeneID)
351065612(GI) NM_068414(refSeq)
CCD61594(EMBL-CDS) WBGene00004374(Ensembl)
O44191(Synonym) BX284604(EMBL)
T11F8.3a(WormBase_TRS)
Show All

PANTHER Classification
PANTHER Family: VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED (PTHR46513)
PANTHER Subfamily: EGF-LIKE DOMAIN-CONTAINING PROTEIN (PTHR46513:SF35)  
PANTHER GO-slim Molecular Function: transmembrane signaling receptor activity
Wnt-protein binding
PANTHER GO-slim Biological Process: canonical Wnt signaling pathway
PANTHER GO-slim Cellular Component: plasma membrane
PANTHER protein class: transmembrane signal receptor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: calcium ion binding, low-density lipoprotein particle receptor activity
GO BP Complete: oocyte development, embryo development ending in birth or egg hatching, ovulation, endocytosis
GO CC Complete: membrane, cytoplasmic vesicle, endosome membrane, plasma membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: MAPK1/MAPK3 signaling, Signaling by Non-Receptor Tyrosine Kinases, Signal Transduction, Intracellular signaling by second messengers, EGFR downregulation, Vesicle-mediated transport, Membrane Trafficking, Signaling by ERBB2, Response to elevated platelet cytosolic Ca2+, GRB2 events in EGFR signaling, Signaling by WNT, SHC1 events in ERBB2 signaling, Signaling by Receptor Tyrosine Kinases, Signaling by Nuclear Receptors, RAF/MAP kinase cascade, Platelet activation, signaling and aggregation, TCF dependent signaling in response to WNT, PIP3 activates AKT signaling, Hemostasis, Downregulation of ERBB2 signaling, MAPK family signaling cascades, Extra-nuclear estrogen signaling, ESR-mediated signaling, Regulation of FZD by ubiquitination, Disassembly of the destruction complex and recruitment of AXIN to the membrane, Signaling by PTK6, ERBB2 Regulates Cell Motility, Clathrin-mediated endocytosis, Cargo recognition for clathrin-mediated endocytosis, ERBB2 Activates PTK6 Signaling, SHC1 events in EGFR signaling, PI3K events in ERBB2 signaling, Platelet degranulation , Signaling by EGFR, Negative regulation of the PI3K/AKT network, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, GAB1 signalosome

Orthologs