PANTHER Gene Information

Gene Symbol(s):

egf.L

Organism:

Xenopus laevis

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Gene Name:

Pro-epidermal growth factor

Gene ID:

egf.L

Protein ID:

A0A8J1MX61

Persistent Id:

PTN009199802

Alternate Ids:

A0A8J1MX61_XENLA(UniProtKB-ID)	XP_041446056(refSeq)
A0A8J1MX61(Synonym)
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PANTHER Classification

PANTHER Family:	VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED (PTHR46513)
PANTHER Subfamily:	PRO-EPIDERMAL GROWTH FACTOR (PTHR46513:SF5)
PANTHER GO-slim Molecular Function:	growth factor activity transmembrane signaling receptor activity Wnt-protein binding
PANTHER GO-slim Biological Process:	canonical Wnt signaling pathway positive regulation of MAPK cascade epidermal growth factor receptor signaling pathway positive regulation of cell population proliferation
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	transmembrane signal receptor

Pathway Categories:

Gonadotropin-releasing hormone receptor pathway

EGF

EGF receptor signaling pathway

Epidermal growth factor

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	growth factor activity
GO BP Complete:	epidermal growth factor receptor signaling pathway, positive regulation of cell population proliferation, positive regulation of MAPK cascade
GO CC Complete:	plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3229\|UniProtKB=P01133	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000016367.5\|UniProtKB=H2QQ13	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000005808.3\|UniProtKB=G3QSQ3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000010043.4\|UniProtKB=F6TFM0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=95290\|UniProtKB=P01132	Mus musculus	LDO
RAT\|RGD=2542\|UniProtKB=P07522	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000009134.5\|UniProtKB=A0A287A231	Sus scrofa	LDO
PIG\|Gene=EGF\|UniProtKB=Q00968	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000010741.4\|UniProtKB=F7B762	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000000506.6\|UniProtKB=A0A5F5Y0J7	Felis catus	O
FELCA\|Gene=EGF\|UniProtKB=Q95ND4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845030111.1\|UniProtKB=A0A8I3Q5L9	Canis lupus familiaris	O
CANLF\|Gene=EGF\|UniProtKB=Q9BEA0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000005870.4\|UniProtKB=F6R392	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000003668.4\|UniProtKB=A0A6I8MYA0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010003806.1\|UniProtKB=A0A8V0XLN7	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010153.4\|UniProtKB=A0A803SU34	Anolis carolinensis	LDO
XENTR\|Xenbase=XB-GENE-951823\|UniProtKB=A8KBG4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000020598.2\|UniProtKB=A0A3B3HR79	Oryzias latipes	LDO
DANRE\|Gene=egf\|UniProtKB=A0A8M2B432	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011771.1\|UniProtKB=W5N1G8	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000017654.2\|UniProtKB=F6WZ22	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000022078.1\|UniProtKB=H2XLM3	Ciona intestinalis	O
BRAFL\|Gene=LOC118427149\|UniProtKB=A0A9J7M3Y3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427146\|UniProtKB=A0A9J7M151	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409884\|UniProtKB=A0A9J7KNA2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427150\|UniProtKB=A0A9J7M0V8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418087\|UniProtKB=A0A9J7LDW4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418084\|UniProtKB=A0A9J7MUW8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427152\|UniProtKB=A0A9J7M0S3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417668\|UniProtKB=A0A9J7MUH3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405902\|UniProtKB=A0A9J7KGA4	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC581905\|UniProtKB=A0A7M7P5D6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105438789\|UniProtKB=A0A7M7PMS8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115923116\|UniProtKB=A0A7M7NNP7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100888447\|UniProtKB=A0A7M7NE90	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446596\|UniProtKB=A0A7M7NG87	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115929295\|UniProtKB=A0A7M7T4T3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC586685\|UniProtKB=A0A7M7RDE0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC594262\|UniProtKB=A0A7M7PLJ1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115925099\|UniProtKB=A0A7M7NZZ2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446106\|UniProtKB=A0A7M7PI37	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105443672\|UniProtKB=A0A7M7HKG7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115924457\|UniProtKB=A0A7M7NVQ1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC591940\|UniProtKB=A0A7M7NLH8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC754161\|UniProtKB=A0A7M7SXU5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446184\|UniProtKB=A0A7M7PJR2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC757083\|UniProtKB=A0A7M7PKJ0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105442855\|UniProtKB=A0A7M7NNI7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115924993\|UniProtKB=A0A7M7NZA2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115923115\|UniProtKB=A0A7M7NND0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105442169\|UniProtKB=A0A7M7NRG6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115923430\|UniProtKB=A0A7M7NQ26	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115926091\|UniProtKB=A0A7M7P7Q5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC587773\|UniProtKB=A0A7M7NGF7	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00004374\|UniProtKB=O44191	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG03794\|UniProtKB=A8WWR1	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00109458\|UniProtKB=A0A2A6BAV3	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00008779\|UniProtKB=G5EFK8	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG09505\|UniProtKB=A8X8Y5	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00038687\|UniProtKB=A8XVN1	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00100282\|UniProtKB=A0A2A6BMJ2	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0011204\|UniProtKB=Q95RU0	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007023\|UniProtKB=Q7QIQ6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC002911\|UniProtKB=D6WHF9	Tribolium castaneum	O
ANOGA\|EnsemblGenome=AGAP008193\|UniProtKB=A0A1S4GXK2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC031834\|UniProtKB=A0A139WA84	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_237349\|UniProtKB=E9G3P6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_314322\|UniProtKB=E9G6S4	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_248813\|UniProtKB=E9GVA3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_303927\|UniProtKB=E9GIG6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_313913\|UniProtKB=E9G5N7	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_303856\|UniProtKB=E9GIF7	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_303858\|UniProtKB=E9GIF9	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_318319\|UniProtKB=E9GIG3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_263601\|UniProtKB=E9HQ28	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_318320\|UniProtKB=E9GIG4	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_303924\|UniProtKB=E9GIG2	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_68539\|UniProtKB=E9I293	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG180677\|UniProtKB=T1FG57	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG178815\|UniProtKB=T1FDS3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG188530\|UniProtKB=T1FQ35	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG170722\|UniProtKB=T1F3D0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG175287\|UniProtKB=T1F941	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG164869\|UniProtKB=T1EVW5	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG185306\|UniProtKB=T1FMN1	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g118240\|UniProtKB=A7SH94	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g177505\|UniProtKB=A7RGB1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g83852\|UniProtKB=A7RJD6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g212268\|UniProtKB=A7SH97	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g245263\|UniProtKB=A7SH96	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g61732\|UniProtKB=A7RIK9	Nematostella vectensis	O