PANTHER Gene Information

Gene Symbol(s):

LRP2

Organism:

Sus scrofa

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Gene Name:

LDL receptor related protein 2

Gene ID:

ENSSSCG00000040746.3

Protein ID:

A0A287AZ36

Persistent Id:

PTN005308879

Alternate Ids:

ENSSSCT00000061421(Ensembl_TRS)	ENSSSCP00000049411(Ensembl_PRO)
A0A287AZ36_PIG(UniProtKB-ID)	A0A287AZ36(Synonym)
ENSSSCG00000040746(Ensembl)
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PANTHER Classification

PANTHER Family:	VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED (PTHR46513)
PANTHER Subfamily:	LDL RECEPTOR RELATED PROTEIN 2 (PTHR46513:SF21)
PANTHER GO-slim Molecular Function:	transmembrane signaling receptor activity Wnt-protein binding
PANTHER GO-slim Biological Process:	canonical Wnt signaling pathway
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	transmembrane signal receptor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	calcium ion binding, protein-folding chaperone binding
GO BP Complete:	cell population proliferation, pulmonary artery morphogenesis, vagina development, coronary artery morphogenesis, male gonad development, protein transport, vitamin D metabolic process, outflow tract septum morphogenesis, sensory perception of sound, phosphatidylinositol 3-kinase/protein kinase B signal transduction, forebrain development, neural tube closure, kidney development, neuron projection arborization, metal ion transport, positive regulation of oligodendrocyte progenitor proliferation, ventricular septum development, response to leptin, cranial skeletal system development, folate import across plasma membrane, receptor-mediated endocytosis, ventricular compact myocardium morphogenesis, negative regulation of BMP signaling pathway, secondary heart field specification, aorta development, negative regulation of apoptotic process, gene expression, diol metabolic process
GO CC Complete:	endocytic vesicle, dendrite, endosome, brush border membrane, clathrin-coated pit, external side of plasma membrane, endoplasmic reticulum, Golgi apparatus, receptor complex, apical plasma membrane, axon

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
GORGO\|Ensembl=ENSGGOG00000016592.3\|UniProtKB=G3RKG1	Gorilla gorilla gorilla	LDO
CHICK\|Ensembl=ENSGALG00010024034.1\|UniProtKB=A0A8V0ZQA7	Gallus gallus	LDO
XENLA\|Gene=lrp2.L\|UniProtKB=A0A8J0TMK5	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-486052\|UniProtKB=A0A6I8RWX3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000005381.2\|UniProtKB=H2LL78	Oryzias latipes	LDO
CIOIN\|Ensembl=ENSCING00000017654.2\|UniProtKB=F6WZ22	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000022078.1\|UniProtKB=H2XLM3	Ciona intestinalis	O
BRAFL\|Gene=LOC118427149\|UniProtKB=A0A9J7M3Y3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427146\|UniProtKB=A0A9J7M151	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409884\|UniProtKB=A0A9J7KNA2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427150\|UniProtKB=A0A9J7M0V8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418087\|UniProtKB=A0A9J7LDW4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418084\|UniProtKB=A0A9J7MUW8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427152\|UniProtKB=A0A9J7M0S3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417668\|UniProtKB=A0A9J7MUH3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405902\|UniProtKB=A0A9J7KGA4	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC581905\|UniProtKB=A0A7M7P5D6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105438789\|UniProtKB=A0A7M7PMS8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115923116\|UniProtKB=A0A7M7NNP7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100888447\|UniProtKB=A0A7M7NE90	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446596\|UniProtKB=A0A7M7NG87	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115929295\|UniProtKB=A0A7M7T4T3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC586685\|UniProtKB=A0A7M7RDE0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC594262\|UniProtKB=A0A7M7PLJ1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115925099\|UniProtKB=A0A7M7NZZ2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446106\|UniProtKB=A0A7M7PI37	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105443672\|UniProtKB=A0A7M7HKG7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115924457\|UniProtKB=A0A7M7NVQ1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC591940\|UniProtKB=A0A7M7NLH8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC754161\|UniProtKB=A0A7M7SXU5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446184\|UniProtKB=A0A7M7PJR2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC757083\|UniProtKB=A0A7M7PKJ0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105442855\|UniProtKB=A0A7M7NNI7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115924993\|UniProtKB=A0A7M7NZA2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115923115\|UniProtKB=A0A7M7NND0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105442169\|UniProtKB=A0A7M7NRG6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115923430\|UniProtKB=A0A7M7NQ26	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115926091\|UniProtKB=A0A7M7P7Q5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC587773\|UniProtKB=A0A7M7NGF7	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00004374\|UniProtKB=O44191	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG03794\|UniProtKB=A8WWR1	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00109458\|UniProtKB=A0A2A6BAV3	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00008779\|UniProtKB=G5EFK8	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG09505\|UniProtKB=A8X8Y5	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00038687\|UniProtKB=A8XVN1	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00100282\|UniProtKB=A0A2A6BMJ2	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0011204\|UniProtKB=Q95RU0	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007023\|UniProtKB=Q7QIQ6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC002911\|UniProtKB=D6WHF9	Tribolium castaneum	O
ANOGA\|EnsemblGenome=AGAP008193\|UniProtKB=A0A1S4GXK2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC031834\|UniProtKB=A0A139WA84	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_237349\|UniProtKB=E9G3P6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_314322\|UniProtKB=E9G6S4	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_248813\|UniProtKB=E9GVA3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_303927\|UniProtKB=E9GIG6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_313913\|UniProtKB=E9G5N7	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_303856\|UniProtKB=E9GIF7	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_303858\|UniProtKB=E9GIF9	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_318319\|UniProtKB=E9GIG3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_263601\|UniProtKB=E9HQ28	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_318320\|UniProtKB=E9GIG4	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_303924\|UniProtKB=E9GIG2	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_68539\|UniProtKB=E9I293	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG180677\|UniProtKB=T1FG57	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG178815\|UniProtKB=T1FDS3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG188530\|UniProtKB=T1FQ35	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG170722\|UniProtKB=T1F3D0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG175287\|UniProtKB=T1F941	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG164869\|UniProtKB=T1EVW5	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG185306\|UniProtKB=T1FMN1	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g118240\|UniProtKB=A7SH94	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g177505\|UniProtKB=A7RGB1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g83852\|UniProtKB=A7RJD6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g212268\|UniProtKB=A7SH97	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g245263\|UniProtKB=A7SH96	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g61732\|UniProtKB=A7RIK9	Nematostella vectensis	O