PANTHER Gene Information   
Gene Symbol(s): KIT
Organism: Gorilla gorilla gorilla
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Gene Name: Mast_stem cell growth factor receptor
Gene ID: ENSGGOG00000015440.3
Protein ID: G3RHF1
Persistent Id: PTN002814380
Alternate Ids:
XM_019025975(refSeq) CABD030031062(EMBL)
G3RHF1(Synonym) 1099256343(GI)
ENSGGOT00000015502(Ensembl_TRS) ENSGGOG00000015440(Ensembl)
ENSGGOP00000015071(Ensembl_PRO) 101126389(GeneID)
G3RHF1_GORGO(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: TYROSINE-PROTEIN KINASE RECEPTOR (PTHR24416)
PANTHER Subfamily: MAST_STEM CELL GROWTH FACTOR RECEPTOR KIT (PTHR24416:SF46)  
PANTHER GO-slim Molecular Function: growth factor binding
transmembrane receptor protein tyrosine kinase activity
PANTHER GO-slim Biological Process: transmembrane receptor protein tyrosine kinase signaling pathway
B cell differentiation
positive regulation of receptor signaling pathway via JAK-STAT
cytokine-mediated signaling pathway
positive regulation of cell migration
positive regulation of MAPK cascade
hematopoietic progenitor cell differentiation
multicellular organism development
regulation of MAP kinase activity
positive regulation of protein serine/threonine kinase activity
PANTHER GO-slim Cellular Component: receptor complex
plasma membrane
PANTHER protein class: transmembrane signal receptor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: placental growth factor receptor activity, growth factor binding, macrophage colony-stimulating factor receptor activity, insulin-like growth factor receptor activity, protease binding, boss receptor activity, hepatocyte growth factor receptor activity, fibroblast growth factor receptor activity, ATP binding, protein tyrosine kinase activity, insulin receptor activity, transmembrane receptor protein tyrosine kinase activity, protein homodimerization activity, stem cell factor receptor activity, brain-derived neurotrophic factor receptor activity, protein tyrosine kinase collagen receptor activity, vascular endothelial growth factor receptor activity, GPI-linked ephrin receptor activity, SH2 domain binding, epidermal growth factor receptor activity, transmembrane-ephrin receptor activity, platelet-derived growth factor beta-receptor activity, platelet-derived growth factor alpha-receptor activity, metal ion binding, histone H2AXY142 kinase activity, histone H3Y41 kinase activity, cytokine binding
GO BP Complete: positive regulation of vascular associated smooth muscle cell differentiation, male gonad development, embryonic hemopoiesis, epidermal growth factor receptor signaling pathway, response to radiation, fibroblast growth factor receptor signaling pathway, negative regulation of developmental process, negative regulation of programmed cell death, mast cell degranulation, lymphoid progenitor cell differentiation, hematopoietic progenitor cell differentiation, glycosphingolipid metabolic process, cell chemotaxis, inflammatory response, melanocyte migration, digestive tract development, myeloid progenitor cell differentiation, pigmentation, melanocyte adhesion, detection of mechanical stimulus involved in sensory perception of sound, intracellular signal transduction, Kit signaling pathway, positive regulation of mast cell cytokine production, ectopic germ cell programmed cell death, vascular endothelial growth factor receptor-1 signaling pathway, B cell differentiation, platelet-derived growth factor receptor-alpha signaling pathway, macrophage colony-stimulating factor signaling pathway, platelet-derived growth factor receptor-beta signaling pathway, insulin-like growth factor receptor signaling pathway, collagen-activated tyrosine kinase receptor signaling pathway, positive regulation of receptor signaling pathway via JAK-STAT, T cell differentiation, hepatocyte growth factor receptor signaling pathway, brain-derived neurotrophic factor receptor signaling pathway, erythrocyte differentiation, immature B cell differentiation, positive regulation of gene expression, ephrin receptor signaling pathway, hematopoietic stem cell migration, negative regulation of reproductive process, positive regulation of cell migration, cell population proliferation, regulation of cell shape, multicellular organism development, insulin receptor signaling pathway, hemopoiesis, Fc receptor signaling pathway, developmental pigmentation, positive regulation of dendritic cell cytokine production, chromatin remodeling, stem cell differentiation, mast cell proliferation, cytokine-mediated signaling pathway, megakaryocyte development, positive regulation of mast cell proliferation, mast cell differentiation, spermatid development, spermatogenesis, vascular endothelial growth factor signaling pathway, erythropoietin-mediated signaling pathway, positive regulation of MAPK cascade, mast cell chemotaxis, regulation of cell population proliferation, ovarian follicle development, melanocyte differentiation, lamellipodium assembly, programmed cell death, actin cytoskeleton organization
GO CC Complete: extracellular space, cell-cell junction, external side of plasma membrane, receptor complex, fibrillar center, plasma membrane, cell surface
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: -

Orthologs