PANTHER Gene Information

Gene Symbol(s):

TGFB1I1

Organism:

Equus caballus

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Gene Name:

Transforming growth factor beta 1 induced transcript 1

Gene ID:

ENSECAG00000001963.3

Protein ID:

F6TPM3

Persistent Id:

PTN009085132

Alternate Ids:

ENSECAT00000002630(Ensembl_TRS)	F6TPM3_HORSE(UniProtKB-ID)
ENSECAG00000001963(Ensembl)	F6TPM3(Synonym)
ENSECAP00000001877(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	PDZ AND LIM DOMAIN PROTEIN ZASP (PTHR24214)
PANTHER Subfamily:	LEUPAXIN (PTHR24214:SF62)
PANTHER GO-slim Molecular Function:	actin binding
PANTHER GO-slim Biological Process:	actin cytoskeleton organization muscle structure development heart development
PANTHER GO-slim Cellular Component:	stress fiber protein-containing complex actin filament adherens junction Z disc
PANTHER protein class:	actin or actin-binding cytoskeletal protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	Roundabout binding, transcription coactivator activity, actin binding, nuclear androgen receptor binding, metal ion binding, muscle alpha-actinin binding, I-SMAD binding
GO BP Complete:	positive regulation of ubiquitin-dependent protein catabolic process, negative regulation of fat cell differentiation, fat cell differentiation, positive regulation of epithelial to mesenchymal transition, epithelial cell differentiation, heart development, positive regulation of DNA-templated transcription, cell fate commitment, Wnt signaling pathway, morphogenesis of embryonic epithelium, muscle structure development, actin cytoskeleton organization, positive regulation of transforming growth factor beta receptor signaling pathway
GO CC Complete:	Z disc, adherens junction, cytoskeleton, anchoring junction, focal adhesion, intracellular membrane-bounded organelle, stress fiber, cytosol, nuclear matrix, filamentous actin

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
ORYLA\|Ensembl=ENSORLG00000022227.1\|UniProtKB=A0A3B3HJ99	Oryzias latipes	LDO
BRAFL\|Gene=LOC118408732\|UniProtKB=A0A9J7HVY3	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC592242\|UniProtKB=A0A7M7NE14	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC585685\|UniProtKB=A0A7M7NES0	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00014262\|UniProtKB=G5EDL9	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00024328\|UniProtKB=A8WP20	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00001132\|UniProtKB=G5EFL5	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG24239\|UniProtKB=A8WKA2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00101087\|UniProtKB=A0A2A6BI24	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0035917\|UniProtKB=Q8IQB4	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP006260\|UniProtKB=A7UU64	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC014041\|UniProtKB=D6WJK4	Tribolium castaneum	O
DROME\|FlyBase=FBgn0259219\|UniProtKB=B7YZE5	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0036044\|UniProtKB=Q9VT49	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0265991\|UniProtKB=A1ZA47	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP003938\|UniProtKB=Q7Q2A8	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP003939\|UniProtKB=Q7PML1	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP003937\|UniProtKB=F5HM25	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP006901\|UniProtKB=Q7PTE3	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC010422\|UniProtKB=A0A139WI59	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC033206\|UniProtKB=A0A139WH76	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_113993\|UniProtKB=E9HGQ6	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW000210\|UniProtKB=B7P6T6	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW022782\|UniProtKB=B7QCQ7	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG192354\|UniProtKB=T1FTU8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG191117\|UniProtKB=T1FSL8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG190914\|UniProtKB=T1FSE9	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g245123\|UniProtKB=A7SGH9	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_25404\|UniProtKB=A9UZB5	Monosiga brevicollis	O