PANTHER Gene Information

Gene Symbol(s):

Zasp66

Organism:

Drosophila melanogaster

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Gene Name:

Z band alternatively spliced PDZ-motif protein 66, isoform E

Gene ID:

FBgn0035917

Protein ID:

Q8IQB4

Persistent Id:

PTN007780115

Alternate Ids:

Q8IQB4_DROME(UniProtKB-ID)	Q8IQB4(Synonym)
28380559(GI)	NM_168283(refSeq)
AAN11990(EMBL-CDS)	FBgn0035917(Ensembl)
FBtr0089561(Ensembl_TRS)	AE014296(EMBL)
FBgn0035917(FlyBase)	FBpp0088529(Ensembl_PRO)
38988(GeneID)
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PANTHER Classification

PANTHER Family:	PDZ AND LIM DOMAIN PROTEIN ZASP (PTHR24214)
PANTHER Subfamily:	Z BAND ALTERNATIVELY SPLICED PDZ-MOTIF PROTEIN 66, ISOFORM E (PTHR24214:SF55)
PANTHER GO-slim Molecular Function:	actin binding
PANTHER GO-slim Biological Process:	actin cytoskeleton organization muscle structure development
PANTHER GO-slim Cellular Component:	stress fiber protein-containing complex actin filament adherens junction Z disc
PANTHER protein class:	actin or actin-binding cytoskeletal protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	actin binding, muscle alpha-actinin binding, protein phosphatase 1 binding
GO BP Complete:	myofibril assembly, mesoderm development, muscle structure development, actin cytoskeleton organization
GO CC Complete:	Z disc, adherens junction, stress fiber, filamentous actin

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=16501\|UniProtKB=P50479	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000017214.6\|UniProtKB=H2QRG2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000010415.3\|UniProtKB=G3R4F9	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000009298.4\|UniProtKB=F7H1G7	Macaca mulatta	O
MOUSE\|MGI=MGI=1353470\|UniProtKB=P70271	Mus musculus	O
RAT\|RGD=3575\|UniProtKB=P36202	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000015426\|UniProtKB=Q3T005	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000014274.5\|UniProtKB=F1RJV5	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000024273.4\|UniProtKB=A0A3Q2H7C0	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000014015.5\|UniProtKB=M3WJX3	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845010145.1\|UniProtKB=A0A8I3NCL1	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000013984.4\|UniProtKB=F6QL09	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000040872.1\|UniProtKB=A0A6I8P217	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010016266\|UniProtKB=Q9PW72	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000027479.3\|UniProtKB=G1KY84	Anolis carolinensis	O
XENLA\|Gene=pdlim4.S\|UniProtKB=A0A1L8GVB1	Xenopus laevis	O
XENLA\|Gene=pdlim4.L\|UniProtKB=Q498K2	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-1001790\|UniProtKB=Q6P3Q7	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000019075.2\|UniProtKB=H2MXV4	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-070308-5\|UniProtKB=Q0PWB9	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000010368.1\|UniProtKB=W5MWE7	lepisosteus oculatus	O
HUMAN\|HGNC=2067\|UniProtKB=O00151	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000002783.6\|UniProtKB=K7CAW2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000014381.3\|UniProtKB=A0A2I2ZBH0	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000000454.4\|UniProtKB=F6YRD0	Macaca mulatta	O
MOUSE\|MGI=MGI=1860611\|UniProtKB=O70400	Mus musculus	O
RAT\|RGD=68324\|UniProtKB=P52944	Rattus norvegicus	O
BOVIN\|Gene=PDLIM1\|UniProtKB=Q5E9E1	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000011182.3\|UniProtKB=A6H7E3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000010493.5\|UniProtKB=F1SC51	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000020816.3\|UniProtKB=A0A9L0S3Z5	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000001420.5\|UniProtKB=M3VWL5	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845022801.1\|UniProtKB=A0A8I3S614	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000005293.4\|UniProtKB=F7DMN3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000005138.3\|UniProtKB=F6WFT9	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010021740.1\|UniProtKB=A0A8V0ZLR0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000012502.4\|UniProtKB=H9GJ06	Anolis carolinensis	O
XENLA\|Gene=pdlim1.S\|UniProtKB=A0A8J1LCJ0	Xenopus laevis	O
XENLA\|Gene=pdlim1.L\|UniProtKB=A0A8J1L489	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-1004691\|UniProtKB=A0A8J0T472	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000014111.2\|UniProtKB=H2MGG2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-5227\|UniProtKB=Q567X7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000011548.1\|UniProtKB=W5N0N0	lepisosteus oculatus	O
HUMAN\|HGNC=13992\|UniProtKB=Q96JY6	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000020062.6\|UniProtKB=H2QVV2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002417.3\|UniProtKB=G3SCD2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000018520.4\|UniProtKB=F7A2X3	Macaca mulatta	O
MOUSE\|MGI=MGI=2384850\|UniProtKB=Q8R1G6	Mus musculus	O
RAT\|RGD=1359203\|UniProtKB=Q6AYD6	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000007369\|UniProtKB=Q3T0C8	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000009625.5\|UniProtKB=A0A8D1S2M8	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000019910.4\|UniProtKB=A0A9L0RGY6	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000005664.6\|UniProtKB=M3W4H1	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845020425.1\|UniProtKB=A0A8I3P9Q2	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000009355.3\|UniProtKB=F7G0B4	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000010783.3\|UniProtKB=F6X407	Ornithorhynchus anatinus	O
ANOCA\|Ensembl=ENSACAG00000039549.1\|UniProtKB=A0A803TGD7	Anolis carolinensis	O
ORYLA\|Ensembl=ENSORLG00000011431.2\|UniProtKB=H2M762	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-070308-4\|UniProtKB=A0A8M3AVD9	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014946.1\|UniProtKB=W5NCP2	lepisosteus oculatus	O
HORSE\|Ensembl=ENSECAG00000001963.3\|UniProtKB=F6TPM3	Equus caballus	O
ORYLA\|Ensembl=ENSORLG00000022227.1\|UniProtKB=A0A3B3HJ99	Oryzias latipes	O
HUMAN\|HGNC=20767\|UniProtKB=Q53GG5	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000016654.6\|UniProtKB=K7DRB5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000001942.3\|UniProtKB=A0A2I2ZNC2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000015407.4\|UniProtKB=F6Q4Z5	Macaca mulatta	O
MOUSE\|MGI=MGI=1859274\|UniProtKB=O70209	Mus musculus	O
RAT\|RGD=620427\|UniProtKB=Q66HS7	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000017183\|UniProtKB=Q3SYZ8	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000015796\|UniProtKB=Q6QGC0	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000017896.4\|UniProtKB=A0A3Q2I6V4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000027240.4\|UniProtKB=M3X5W3	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845021187.1\|UniProtKB=A0A8I3PBJ5	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000047795.1\|UniProtKB=A0A5F8GHU1	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000013438.3\|UniProtKB=F7FIF9	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010016991.1\|UniProtKB=A0A8V0YSJ5	Gallus gallus	O
CHICK\|Gene=PDLIM3\|UniProtKB=Q9PU47	Gallus gallus	O
XENLA\|Gene=pdlim3.S\|UniProtKB=A0A8J0U8F5	Xenopus laevis	O
XENLA\|Gene=pdlim3\|UniProtKB=Q6GLJ6	Xenopus laevis	O
XENLA\|Gene=pdlim3.L\|UniProtKB=A0A8J0UBY1	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-942925\|UniProtKB=A0A6I8QUD5	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000008226.2\|UniProtKB=H2LW42	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050505-1\|UniProtKB=Q4VBT3	Danio rerio	O
DANRE\|Gene=pdlim3b\|UniProtKB=A0A8M2B416	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000013811.1\|UniProtKB=W5N8S4	lepisosteus oculatus	O
BRAFL\|Gene=LOC118408732\|UniProtKB=A0A9J7HVY3	Branchiostoma floridae	O
HUMAN\|HGNC=17468\|UniProtKB=Q96HC4	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000016292.6\|UniProtKB=H2QPW7	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000024845.2\|UniProtKB=A0A2I2Y405	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000022246.4\|UniProtKB=A0A5F7ZFI6	Macaca mulatta	O
MOUSE\|MGI=MGI=1927489\|UniProtKB=Q8CI51	Mus musculus	O
RAT\|RGD=621076\|UniProtKB=Q62920	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000012818.6\|UniProtKB=G3MY19	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000009192.5\|UniProtKB=A0A287A1G4	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000016733.4\|UniProtKB=A0A5F5PHG7	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000026158.4\|UniProtKB=A0A5F5Y344	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845020888.1\|UniProtKB=A0A8I3PAU7	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000019264.4\|UniProtKB=A0A5F8GGK5	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000048250.1\|UniProtKB=A0A6I8PEI8	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010004312.1\|UniProtKB=A0A8V0XNV6	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000013613.4\|UniProtKB=A0A803TFG2	Anolis carolinensis	O
XENLA\|Gene=pdlim5.L\|UniProtKB=A0A8J1M0M6	Xenopus laevis	O
XENLA\|Gene=pdlim5.S\|UniProtKB=A0A8J1LQC7	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-854114\|UniProtKB=A0A6I8SHL5	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000007854.2\|UniProtKB=A0A3B3IF17	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000005537.2\|UniProtKB=A0A3B3HQX2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040426-908\|UniProtKB=Q7ZVC1	Danio rerio	O
DANRE\|Gene=pdlim5a\|UniProtKB=A0A8M6Z6A6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000012933.1\|UniProtKB=W5N5M3	lepisosteus oculatus	O
HUMAN\|HGNC=15710\|UniProtKB=O75112	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000002705.7\|UniProtKB=A0A2I3RJY6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000013070.3\|UniProtKB=G3RBB2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000003608.4\|UniProtKB=A0A1D5REX0	Macaca mulatta	O
MOUSE\|MGI=MGI=1344412\|UniProtKB=Q9JKS4	Mus musculus	O
RAT\|RGD=1564875\|UniProtKB=A0A096MJ01	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000018707.6\|UniProtKB=G3N3C9	Bos taurus	O
HORSE\|Ensembl=ENSECAG00000024538.4\|UniProtKB=A0A5F5Q0G6	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000015019.6\|UniProtKB=A0A2I2U774	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845006724.1\|UniProtKB=A0A8I3RTI3	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000011146.4\|UniProtKB=A0A5F8H8D4	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000008906.4\|UniProtKB=A0A6I8N779	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010010438.1\|UniProtKB=A0A8V0Y5F5	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000014492.4\|UniProtKB=A0A803U066	Anolis carolinensis	O
XENLA\|Gene=ldb3.S\|UniProtKB=A0A8J1LBD1	Xenopus laevis	O
XENLA\|Gene=LOC108696280\|UniProtKB=A0A8J1L5P5	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-922381\|UniProtKB=A0A8J0T5B6	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000002622.2\|UniProtKB=H2LBJ3	Oryzias latipes	O
DANRE\|Gene=ldb3a\|UniProtKB=A0A8M9Q9Y7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000012484.1\|UniProtKB=W5N407	lepisosteus oculatus	O
HUMAN\|HGNC=16805\|UniProtKB=Q2TBC4	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000018160.6\|UniProtKB=H2R2U9	Pan troglodytes	O
MOUSE\|MGI=MGI=2685785\|UniProtKB=F6ZPB0	Mus musculus	O
RAT\|RGD=1563979\|UniProtKB=F1M759	Rattus norvegicus	O
HORSE\|Ensembl=ENSECAG00000017961.4\|UniProtKB=A0A9L0TF00	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000023605.4\|UniProtKB=M3WY10	Felis catus	O
MONDO\|Ensembl=ENSMODG00000012839.4\|UniProtKB=F7CTK8	Monodelphis domestica	O
HUMAN\|HGNC=22958\|UniProtKB=Q9NR12	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000017587.6\|UniProtKB=A0A2I3SZY4	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000014435.3\|UniProtKB=G3REV3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000003146.4\|UniProtKB=I0FWE5	Macaca mulatta	O
MOUSE\|MGI=MGI=1914649\|UniProtKB=Q3TJD7	Mus musculus	O
RAT\|RGD=628769\|UniProtKB=Q9Z1Z9	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000011400\|UniProtKB=Q3SX40	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000040507.3\|UniProtKB=A0A8W4FLI0	Sus scrofa	O
FELCA\|Ensembl=ENSFCAG00000025601.4\|UniProtKB=M3XFE3	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845030304.1\|UniProtKB=A0A8I3QB47	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845009567.1\|UniProtKB=A0A8I3N7X4	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000004669.4\|UniProtKB=F6VG61	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000045497.1\|UniProtKB=A0A6I8NPK8	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010009028.1\|UniProtKB=A0A8V0Y8I1	Gallus gallus	O
CHICK\|Gene_ORFName=RCJMB04_14g20\|UniProtKB=Q679P3	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000005968.4\|UniProtKB=G1KEW4	Anolis carolinensis	O
XENLA\|Gene=pdlim7.L\|UniProtKB=A0A1L8GXV3	Xenopus laevis	O
XENLA\|Gene=pdlim7\|UniProtKB=Q6INU3	Xenopus laevis	O
ORYLA\|Ensembl=ENSORLG00000006787.2\|UniProtKB=H2LR31	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040426-2092\|UniProtKB=Q6P7E4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000011920.1\|UniProtKB=W5N202	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000023912.1\|UniProtKB=H2XKB3	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000001795.2\|UniProtKB=F6X5Z3	Ciona intestinalis	O
BRAFL\|Gene=LOC118412353\|UniProtKB=A0A9J7KW32	Branchiostoma floridae	O
BRAFL\|Gene=LOC118415165\|UniProtKB=A0A9J7MQM9	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC592242\|UniProtKB=A0A7M7NE14	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC585685\|UniProtKB=A0A7M7NES0	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00014262\|UniProtKB=G5EDL9	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00024328\|UniProtKB=A8WP20	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00001132\|UniProtKB=G5EFL5	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG24239\|UniProtKB=A8WKA2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00101087\|UniProtKB=A0A2A6BI24	Pristionchus pacificus	O
ANOGA\|EnsemblGenome=AGAP006260\|UniProtKB=A7UU64	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC014041\|UniProtKB=D6WJK4	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_113993\|UniProtKB=E9HGQ6	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW000210\|UniProtKB=B7P6T6	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW022782\|UniProtKB=B7QCQ7	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG192354\|UniProtKB=T1FTU8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG191117\|UniProtKB=T1FSL8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG190914\|UniProtKB=T1FSE9	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g245123\|UniProtKB=A7SGH9	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_25404\|UniProtKB=A9UZB5	Monosiga brevicollis	O