PANTHER Gene Information

Gene Symbol(s):

ERCC3

Organism:

Equus caballus

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Gene Name:

General transcription and DNA repair factor IIH helicase subunit XPB

Gene ID:

ENSECAG00000006589.4

Protein ID:

A0A9L0S5D3

Persistent Id:

PTN008965028

Alternate Ids:

ENSECAG00000006589(Ensembl)	A0A9L0S5D3_HORSE(UniProtKB-ID)
ENSECAT00000122776(Ensembl_TRS)	A0A9L0S5D3(Synonym)
ENSECAP00000070061(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	RAD25/XP-B DNA REPAIR HELICASE (PTHR11274)
PANTHER Subfamily:	GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB (PTHR11274:SF0)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	DNA helicase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP hydrolysis activity, DNA binding, ATP binding, DNA helicase activity, double-stranded DNA helicase activity, helicase activity, four-way junction helicase activity, forked DNA-dependent helicase activity, single-stranded 3'-5' DNA helicase activity, 3'-5' DNA helicase activity, hydrolase activity, isomerase activity
GO BP Complete:	DNA repair, nucleotide-excision repair, DNA duplex unwinding, regulation of mitotic cell cycle phase transition, transcription-coupled nucleotide-excision repair, protein localization, nucleotide-excision repair, transcription by RNA polymerase II, response to UV, embryonic organ development, DNA topological change, transcription initiation at RNA polymerase II promoter, response to oxidative stress, DNA duplex unwinding, apoptotic process, positive regulation of apoptotic process, hair cell differentiation
GO CC Complete:	nucleus, transcription preinitiation complex, transcription factor TFIID complex, transcription factor TFIIH core complex, transcription factor TFIIH holo complex, nucleotide-excision repair factor 3 complex, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3435\|UniProtKB=P19447	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000046940.1\|UniProtKB=K7AI54	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015255.3\|UniProtKB=G3RGX4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000064234.1\|UniProtKB=H9FR52	Macaca mulatta	LDO
MOUSE\|MGI=MGI=95414\|UniProtKB=P49135	Mus musculus	LDO
RAT\|RGD=1307139\|UniProtKB=Q4G005	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000020777\|UniProtKB=Q1RMT1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000015721.5\|UniProtKB=F1RXZ5	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000006989.6\|UniProtKB=M3W6V7	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845022679.1\|UniProtKB=A0A8I3PFQ7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000018695.4\|UniProtKB=F7FQP6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000046724.1\|UniProtKB=A0A6I8NFW1	Ornithorhynchus anatinus	LDO
CHICK\|Gene_ORFName=RCJMB04_10e8\|UniProtKB=Q5ZKK7	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010021290.1\|UniProtKB=F1NZ23	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000009919.4\|UniProtKB=H9GFX2	Anolis carolinensis	LDO
XENLA\|Gene=ercc3.L\|UniProtKB=A0A1L8EVD2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1009820\|UniProtKB=F6UIE1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000004393.2\|UniProtKB=H2LHP6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-3043\|UniProtKB=Q7ZVV1	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000010907.1\|UniProtKB=W5MYC3	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000002867.3\|UniProtKB=F6TML4	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_126483\|UniProtKB=C3YBY7	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC105444553\|UniProtKB=A0A7M7STB7	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC589434\|UniProtKB=A0A7M7P5G4	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00013441\|UniProtKB=Q95PZ4	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG13269\|UniProtKB=A8XHG0	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00092190\|UniProtKB=A0A2A6BPJ5	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0001179\|UniProtKB=Q02870	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP028632\|UniProtKB=A0A1S4HDZ5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC003167\|UniProtKB=D6WEU3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_300803\|UniProtKB=E9G6B4	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW023179\|UniProtKB=B7QGL8	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG155693\|UniProtKB=T1ELK7	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g96883\|UniProtKB=A7RXK7	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG22911\|UniProtKB=B3RTG7	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_32554\|UniProtKB=A9V0A0	Monosiga brevicollis	LDO
YEAST\|SGD=S000001405\|UniProtKB=Q00578	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR280W\|UniProtKB=Q753N2	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000180210\|UniProtKB=A0A1D8PSC6	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_B11726g\|UniProtKB=Q6CEZ1	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_08201\|UniProtKB=C8V766	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G03320\|UniProtKB=Q4WEK4	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU06438\|UniProtKB=Q7RYX9	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_07704\|UniProtKB=A7EQV1	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_11221\|UniProtKB=Q0UAJ3	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC17A5.06\|UniProtKB=O13768	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03206\|UniProtKB=B6K3L6	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNA05940\|UniProtKB=Q5KNM9	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_04069\|UniProtKB=A0A0D1CMZ9	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_13525\|UniProtKB=E3KTN8	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_33160\|UniProtKB=F4P1G9	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_20761\|UniProtKB=F4PBE6	Batrachochytrium dendrobatidis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_34108\|UniProtKB=F4NVP0	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_077260\|UniProtKB=C4M2T5	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_088430\|UniProtKB=C4MA19	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0280913\|UniProtKB=Q54UP1	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0278729\|UniProtKB=O00835	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_96425\|UniProtKB=F0Z866	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_29_0590\|UniProtKB=E9ADR1	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.3.5100\|UniProtKB=Q580W5	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_31_0070\|UniProtKB=Q4Q6Q7	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.389.1430\|UniProtKB=Q389B2	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_32_3920\|UniProtKB=Q4Q4N0	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.01.7950\|UniProtKB=Q381F9	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_5910\|UniProtKB=A8B707	Giardia intestinalis	O
GIAIC\|EnsemblGenome=GL50803_16512\|UniProtKB=A8BMI7	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_044250\|UniProtKB=A2E0I3	Trichomonas vaginalis	LDO
TRIV3\|Gene_ORFName=TVAG_167010\|UniProtKB=A2DEA8	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_1037600\|UniProtKB=Q8IJ31	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00004916001\|UniProtKB=A0BJ26	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016096001\|UniProtKB=A0DDY7	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_33970\|UniProtKB=B8C0Y9	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GAU9_PHYRM\|UniProtKB=H3GAU9	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_06g297016v5\|UniProtKB=A0A2K3DQN1	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00001p00265330\|UniProtKB=W1NLX9	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_42G00800\|UniProtKB=A0A0K9P1V9	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma09_g20910\|UniProtKB=A0A804KLX6	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_000506mg\|UniProtKB=K3XF39	Setaria italica	O
SETIT\|EnsemblGenome=SETIT_009434mg\|UniProtKB=K3Y5E6	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3003G264100\|UniProtKB=C5XGX0	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb156220\|UniProtKB=A0A1D6NF15	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os01g0691600\|UniProtKB=Q0JK78	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g47090v3\|UniProtKB=I1HQK0	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0281430\|UniProtKB=F2DNX2	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS3B02G294400\|UniProtKB=A0A077S2D9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G261300\|UniProtKB=A0A3B6EJQ3	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS3D02G261400\|UniProtKB=A0A3B6GYA5	Triticum aestivum	LDO
NELNU\|Gene=LOC104610652\|UniProtKB=A0A1U8B7X3	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110797073\|UniProtKB=A0A9R0IZD0	Spinacia oleracea	O
SPIOL\|Gene=LOC110797022\|UniProtKB=A0A9R0K521	Spinacia oleracea	O
SPIOL\|Gene=LOC110805197\|UniProtKB=A0A9R0JGG4	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0240871\|UniProtKB=A0A251UF11	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr17g0779301\|UniProtKB=A0A9K3DEG7	Helianthus annuus	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr17g0533461\|UniProtKB=A0A251RPT0	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C200094730\|UniProtKB=A0A9R1XSY4	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C300104740\|UniProtKB=A0A9R1XNA6	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a001651mg\|UniProtKB=A0A022RI41	Erythranthe guttata	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400026783\|UniProtKB=M1CJL7	Solanum tuberosum	O
TOBAC\|Gene=LOC107807765\|UniProtKB=A0A1S4BFT1	Nicotiana tabacum	O
TOBAC\|Gene=LOC107780339\|UniProtKB=A0A1S3YWE0	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_00255\|UniProtKB=A0A2G3ADW1	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400012332\|UniProtKB=M1AWX3	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc08g081340.3\|UniProtKB=A0A3Q7HUB7	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107797856\|UniProtKB=A0A1S4AI24	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107817044\|UniProtKB=A0A1S4CAY7	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107819093\|UniProtKB=A0A1S4CHR8	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi02g00009\|UniProtKB=F6HUL9	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_E00638\|UniProtKB=A0A059C1U8	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00081897001\|UniProtKB=A0A078I7L0	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C04P48400.1\|UniProtKB=A0A078J769	Brassica napus	LDO
BRANA\|Gene_ORFName=GSBRNA2T00068530001\|UniProtKB=A0A078HPF9	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra028496\|UniProtKB=M4EI81	Brassica campestris	O
BRACM\|EnsemblGenome=Bra025503\|UniProtKB=M4E9P7	Brassica campestris	LDO
ARATH\|TAIR=locus=2177891\|UniProtKB=Q9FUG4	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2177901\|UniProtKB=Q38861	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107924629\|UniProtKB=A0A1U8LBW8	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107929280\|UniProtKB=A0A1U8LNK1	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_016301\|UniProtKB=A0A061G5Y0	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g010184mg\|UniProtKB=A0A067G9E9	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_001G101300v3\|UniProtKB=A0A2K2BVF1	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_02G021700\|UniProtKB=A0A2C9WCR4	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1687530\|UniProtKB=B9RCF1	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_05G209700\|UniProtKB=I1K6G2	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G016400\|UniProtKB=I1KPD4	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_8g098675\|UniProtKB=A0A072TW37	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr09_10770\|UniProtKB=A0A2I4FCA6	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_5G152930\|UniProtKB=A0A0A0KKI0	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_5G104000\|UniProtKB=A0A251P6H7	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_147068\|UniProtKB=D8RGS1	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_230853\|UniProtKB=D8R6I4	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_418040\|UniProtKB=D8S4G6	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_109026\|UniProtKB=D8S5D4	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c6_13890\|UniProtKB=A9T7C2	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0037s0100\|UniProtKB=A0A2R6X496	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000660070\|UniProtKB=A0A1Y1HS32	Klebsormidium nitens	LDO
KORCO\|EnsemblGenome=Kcr_0606\|UniProtKB=B1L4I0	Korarchaeum cryptofilum	LDO
SACS2\|EnsemblGenome=SSO0959\|UniProtKB=Q97ZF9	Sulfolobus solfataricus	O
SACS2\|EnsemblGenome=SSO0473\|UniProtKB=Q97ZV2	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE2446\|UniProtKB=Q8ZV59	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_2403\|UniProtKB=Q8TN90	Methanosarcina acetivorans	LDO
HALSA\|EnsemblGenome=VNG_6130G\|UniProtKB=O51997	Halobacterium salinarum	LDO
THEKO\|EnsemblGenome=TK0928\|UniProtKB=Q5JI91	Thermococcus kodakaraensis	LDO
KORCO\|EnsemblGenome=Kcr_1550\|UniProtKB=B1L767	Korarchaeum cryptofilum	O
PYRAE\|EnsemblGenome=PAE1611\|UniProtKB=Q8ZWU9	Pyrobaculum aerophilum	O
HALSA\|EnsemblGenome=VNG_1406G\|UniProtKB=Q9HPZ2	Halobacterium salinarum	O
MYCTU\|Gene_OrderedLocusName=Rv0861c\|UniProtKB=O53873	Mycobacterium tuberculosis	LDO
DEIRA\|EnsemblGenome=DR_A0131\|UniProtKB=Q9RZ22	Deinococcus radiodurans	LDO
LEPIN\|EnsemblGenome=LA_2129\|UniProtKB=Q8F4B2	Leptospira interrogans	LDO
FUSNN\|EnsemblGenome=FN0448\|UniProtKB=Q8RG69	Fusobacterium nucleatum	LDO
HELPY\|EnsemblGenome=HP_0668\|UniProtKB=O25379	Helicobacter pylori	LDO
YERPE\|Gene_OrderedLocusName=YPMT1.30\|UniProtKB=A0A5P8YMT8	Yersinia pestis	LDO