PANTHER Gene Information

Gene Symbol(s):

XPB

Organism:

Trypanosoma brucei

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Gene Name:

TFIIH basal transcription factor complex helicase XPB subunit

Gene ID:

Tb927.3.5100

Protein ID:

Q580W5

Persistent Id:

PTN002259168

Alternate Ids:

3656453(GeneID)	XPB(Synonym)
AAZ10541(EMBL-CDS)	62360608(GI)
D6XE64(AltAccession)	XM_839007(refSeq)
3.6.4.12(EC)	XPB_TRYB2(UniProtKB-ID)
XPB{ECO:0000303\|PubMed:17259543}(Symbol)	AC093543(EMBL)
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PANTHER Classification

PANTHER Family:	RAD25/XP-B DNA REPAIR HELICASE (PTHR11274)
PANTHER Subfamily:	TFIIH BASAL TRANSCRIPTION FACTOR COMPLEX HELICASE XPB SUBUNIT (PTHR11274:SF16)
PANTHER GO-slim Molecular Function:	3'-5' DNA helicase activity
PANTHER GO-slim Biological Process:	transcription initiation at RNA polymerase II promoter
PANTHER GO-slim Cellular Component:	transcription factor TFIIH holo complex nucleotide-excision repair complex protein-DNA complex
PANTHER protein class:	DNA helicase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA-binding transcription factor activity, 3'-5' DNA helicase activity
GO BP Complete:	transcription initiation at RNA polymerase II promoter
GO CC Complete:	nucleus, transcription preinitiation complex, cytoplasm, transcription factor TFIIH holo complex, nucleotide-excision repair factor 3 complex, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3435\|UniProtKB=P19447	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000046940.1\|UniProtKB=K7AI54	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000015255.3\|UniProtKB=G3RGX4	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000064234.1\|UniProtKB=H9FR52	Macaca mulatta	O
MOUSE\|MGI=MGI=95414\|UniProtKB=P49135	Mus musculus	O
RAT\|RGD=1307139\|UniProtKB=Q4G005	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000020777\|UniProtKB=Q1RMT1	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000015721.5\|UniProtKB=F1RXZ5	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000006589.4\|UniProtKB=A0A9L0S5D3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000006989.6\|UniProtKB=M3W6V7	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845022679.1\|UniProtKB=A0A8I3PFQ7	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000018695.4\|UniProtKB=F7FQP6	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000046724.1\|UniProtKB=A0A6I8NFW1	Ornithorhynchus anatinus	O
CHICK\|Gene_ORFName=RCJMB04_10e8\|UniProtKB=Q5ZKK7	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010021290.1\|UniProtKB=F1NZ23	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000009919.4\|UniProtKB=H9GFX2	Anolis carolinensis	O
XENLA\|Gene=ercc3.L\|UniProtKB=A0A1L8EVD2	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-1009820\|UniProtKB=F6UIE1	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000004393.2\|UniProtKB=H2LHP6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-3043\|UniProtKB=Q7ZVV1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000010907.1\|UniProtKB=W5MYC3	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000002867.3\|UniProtKB=F6TML4	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_126483\|UniProtKB=C3YBY7	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC105444553\|UniProtKB=A0A7M7STB7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC589434\|UniProtKB=A0A7M7P5G4	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00013441\|UniProtKB=Q95PZ4	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13269\|UniProtKB=A8XHG0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00092190\|UniProtKB=A0A2A6BPJ5	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0001179\|UniProtKB=Q02870	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP028632\|UniProtKB=A0A1S4HDZ5	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003167\|UniProtKB=D6WEU3	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_300803\|UniProtKB=E9G6B4	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW023179\|UniProtKB=B7QGL8	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG155693\|UniProtKB=T1ELK7	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g96883\|UniProtKB=A7RXK7	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG22911\|UniProtKB=B3RTG7	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_32554\|UniProtKB=A9V0A0	Monosiga brevicollis	O
YEAST\|SGD=S000001405\|UniProtKB=Q00578	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AFR280W\|UniProtKB=Q753N2	Eremothecium gossypii	O
CANAL\|CGD=CAL0000180210\|UniProtKB=A0A1D8PSC6	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_B11726g\|UniProtKB=Q6CEZ1	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_08201\|UniProtKB=C8V766	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G03320\|UniProtKB=Q4WEK4	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU06438\|UniProtKB=Q7RYX9	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_07704\|UniProtKB=A7EQV1	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_11221\|UniProtKB=Q0UAJ3	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC17A5.06\|UniProtKB=O13768	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_03206\|UniProtKB=B6K3L6	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNA05940\|UniProtKB=Q5KNM9	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_04069\|UniProtKB=A0A0D1CMZ9	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_13525\|UniProtKB=E3KTN8	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_33160\|UniProtKB=F4P1G9	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_20761\|UniProtKB=F4PBE6	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_34108\|UniProtKB=F4NVP0	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_077260\|UniProtKB=C4M2T5	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_088430\|UniProtKB=C4MA19	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0280913\|UniProtKB=Q54UP1	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0278729\|UniProtKB=O00835	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_96425\|UniProtKB=F0Z866	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_29_0590\|UniProtKB=E9ADR1	Leishmania major	LDO
GIAIC\|EnsemblGenome=GL50803_5910\|UniProtKB=A8B707	Giardia intestinalis	O
GIAIC\|EnsemblGenome=GL50803_16512\|UniProtKB=A8BMI7	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_044250\|UniProtKB=A2E0I3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_167010\|UniProtKB=A2DEA8	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_1037600\|UniProtKB=Q8IJ31	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00004916001\|UniProtKB=A0BJ26	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016096001\|UniProtKB=A0DDY7	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_33970\|UniProtKB=B8C0Y9	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GAU9_PHYRM\|UniProtKB=H3GAU9	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_06g297016v5\|UniProtKB=A0A2K3DQN1	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00001p00265330\|UniProtKB=W1NLX9	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_42G00800\|UniProtKB=A0A0K9P1V9	Zostera marina	O
MUSAM\|EnsemblGenome=Ma09_g20910\|UniProtKB=A0A804KLX6	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_000506mg\|UniProtKB=K3XF39	Setaria italica	O
SETIT\|EnsemblGenome=SETIT_009434mg\|UniProtKB=K3Y5E6	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3003G264100\|UniProtKB=C5XGX0	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb156220\|UniProtKB=A0A1D6NF15	Zea mays	O
ORYSJ\|EnsemblGenome=Os01g0691600\|UniProtKB=Q0JK78	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_2g47090v3\|UniProtKB=I1HQK0	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0281430\|UniProtKB=F2DNX2	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS3B02G294400\|UniProtKB=A0A077S2D9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G261300\|UniProtKB=A0A3B6EJQ3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3D02G261400\|UniProtKB=A0A3B6GYA5	Triticum aestivum	O
NELNU\|Gene=LOC104610652\|UniProtKB=A0A1U8B7X3	Nelumbo nucifera	O
SPIOL\|Gene=LOC110797073\|UniProtKB=A0A9R0IZD0	Spinacia oleracea	O
SPIOL\|Gene=LOC110797022\|UniProtKB=A0A9R0K521	Spinacia oleracea	O
SPIOL\|Gene=LOC110805197\|UniProtKB=A0A9R0JGG4	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0240871\|UniProtKB=A0A251UF11	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr17g0779301\|UniProtKB=A0A9K3DEG7	Helianthus annuus	O
HELAN\|Gene_ORFName=HannXRQ_Chr17g0533461\|UniProtKB=A0A251RPT0	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C200094730\|UniProtKB=A0A9R1XSY4	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C300104740\|UniProtKB=A0A9R1XNA6	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a001651mg\|UniProtKB=A0A022RI41	Erythranthe guttata	O
SOLTU\|EnsemblGenome=PGSC0003DMG400026783\|UniProtKB=M1CJL7	Solanum tuberosum	O
TOBAC\|Gene=LOC107807765\|UniProtKB=A0A1S4BFT1	Nicotiana tabacum	O
TOBAC\|Gene=LOC107780339\|UniProtKB=A0A1S3YWE0	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_00255\|UniProtKB=A0A2G3ADW1	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400012332\|UniProtKB=M1AWX3	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc08g081340.3\|UniProtKB=A0A3Q7HUB7	Solanum lycopersicum	O
TOBAC\|Gene=LOC107797856\|UniProtKB=A0A1S4AI24	Nicotiana tabacum	O
TOBAC\|Gene=LOC107817044\|UniProtKB=A0A1S4CAY7	Nicotiana tabacum	O
TOBAC\|Gene=LOC107819093\|UniProtKB=A0A1S4CHR8	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi02g00009\|UniProtKB=F6HUL9	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_E00638\|UniProtKB=A0A059C1U8	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00081897001\|UniProtKB=A0A078I7L0	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C04P48400.1\|UniProtKB=A0A078J769	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00068530001\|UniProtKB=A0A078HPF9	Brassica napus	O
BRACM\|EnsemblGenome=Bra028496\|UniProtKB=M4EI81	Brassica campestris	O
BRACM\|EnsemblGenome=Bra025503\|UniProtKB=M4E9P7	Brassica campestris	O
ARATH\|TAIR=locus=2177891\|UniProtKB=Q9FUG4	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2177901\|UniProtKB=Q38861	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107924629\|UniProtKB=A0A1U8LBW8	Gossypium hirsutum	O
GOSHI\|Gene=LOC107929280\|UniProtKB=A0A1U8LNK1	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_016301\|UniProtKB=A0A061G5Y0	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g010184mg\|UniProtKB=A0A067G9E9	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_001G101300v3\|UniProtKB=A0A2K2BVF1	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_02G021700\|UniProtKB=A0A2C9WCR4	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1687530\|UniProtKB=B9RCF1	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_05G209700\|UniProtKB=I1K6G2	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G016400\|UniProtKB=I1KPD4	Glycine max	O
MEDTR\|EnsemblGenome=MTR_8g098675\|UniProtKB=A0A072TW37	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr09_10770\|UniProtKB=A0A2I4FCA6	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_5G152930\|UniProtKB=A0A0A0KKI0	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_5G104000\|UniProtKB=A0A251P6H7	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_147068\|UniProtKB=D8RGS1	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_230853\|UniProtKB=D8R6I4	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_418040\|UniProtKB=D8S4G6	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_109026\|UniProtKB=D8S5D4	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c6_13890\|UniProtKB=A9T7C2	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0037s0100\|UniProtKB=A0A2R6X496	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000660070\|UniProtKB=A0A1Y1HS32	Klebsormidium nitens	O
KORCO\|EnsemblGenome=Kcr_0606\|UniProtKB=B1L4I0	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO0959\|UniProtKB=Q97ZF9	Sulfolobus solfataricus	O
SACS2\|EnsemblGenome=SSO0473\|UniProtKB=Q97ZV2	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE2446\|UniProtKB=Q8ZV59	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_2403\|UniProtKB=Q8TN90	Methanosarcina acetivorans	O
HALSA\|EnsemblGenome=VNG_6130G\|UniProtKB=O51997	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK0928\|UniProtKB=Q5JI91	Thermococcus kodakaraensis	O
KORCO\|EnsemblGenome=Kcr_1550\|UniProtKB=B1L767	Korarchaeum cryptofilum	O
PYRAE\|EnsemblGenome=PAE1611\|UniProtKB=Q8ZWU9	Pyrobaculum aerophilum	O
HALSA\|EnsemblGenome=VNG_1406G\|UniProtKB=Q9HPZ2	Halobacterium salinarum	O
MYCTU\|Gene_OrderedLocusName=Rv0861c\|UniProtKB=O53873	Mycobacterium tuberculosis	O
DEIRA\|EnsemblGenome=DR_A0131\|UniProtKB=Q9RZ22	Deinococcus radiodurans	O
LEPIN\|EnsemblGenome=LA_2129\|UniProtKB=Q8F4B2	Leptospira interrogans	O
FUSNN\|EnsemblGenome=FN0448\|UniProtKB=Q8RG69	Fusobacterium nucleatum	O
HELPY\|EnsemblGenome=HP_0668\|UniProtKB=O25379	Helicobacter pylori	O
YERPE\|Gene_OrderedLocusName=YPMT1.30\|UniProtKB=A0A5P8YMT8	Yersinia pestis	O