PANTHER Gene Information   
Gene Symbol(s): BLM
Organism: Equus caballus
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Gene Name: DNA helicase
Gene ID: ENSECAG00000011405.4
Protein ID: A0A9L0S401
Persistent Id: PTN001415794
Alternate Ids:
A0A9L0S401(Synonym) A0A9L0S401_HORSE(UniProtKB-ID)
ENSECAP00000068873(Ensembl_PRO) ENSECAG00000011405(Ensembl)
ENSECAT00000141442(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: DNA HELICASE RECQ FAMILY MEMBER (PTHR13710)
PANTHER Subfamily: RECQ-LIKE DNA HELICASE BLM (PTHR13710:SF153)  
PANTHER GO-slim Molecular Function: 3'-5' DNA helicase activity
PANTHER GO-slim Biological Process: DNA unwinding involved in DNA replication
double-strand break repair via homologous recombination
PANTHER GO-slim Cellular Component: nucleus
cytoplasm
chromosome
PANTHER protein class: DNA helicase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: helicase activity, four-way junction helicase activity, single-stranded DNA binding, ATP binding, p53 binding, G-quadruplex DNA binding, isomerase activity, ATP-dependent activity, acting on DNA, zinc ion binding, identical protein binding, protein homodimerization activity, double-stranded DNA helicase activity, 8-hydroxy-2'-deoxyguanosine DNA binding, bubble DNA binding, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, Y-form DNA binding, forked DNA-dependent helicase activity, 3'-5' DNA helicase activity, four-way junction DNA binding, telomeric D-loop binding, DNA binding, DNA helicase activity, telomeric G-quadruplex DNA binding, DNA/DNA annealing activity, single-stranded 3'-5' DNA helicase activity, hydrolase activity
GO BP Complete: DNA repair, mitotic G2 DNA damage checkpoint signaling, response to X-ray, DNA double-strand break processing, G-quadruplex DNA unwinding, DNA replication, double-strand break repair via homologous recombination, DNA recombination, protein homooligomerization, telomere maintenance, DNA damage response, telomeric D-loop disassembly, DNA unwinding involved in DNA replication, negative regulation of DNA recombination, positive regulation of DNA-templated transcription, negative regulation of cell division, DNA duplex unwinding, cellular response to ionizing radiation, resolution of DNA recombination intermediates, cellular response to hydroxyurea, replication fork processing, protein complex oligomerization, cellular response to camptothecin, regulation of DNA-templated DNA replication
GO CC Complete: PML body, nuclear chromosome, lateral element, chromosome, nucleolus, nucleoplasm, chromosome, telomeric region, nucleus, cytoplasm, cytosol, nuclear matrix, protein-containing complex, RecQ family helicase-topoisomerase III complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: -

Orthologs