PANTHER Gene Information

Gene Symbol(s):

GDF3

Organism:

Equus caballus

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Gene Name:

Growth differentiation factor 3

Gene ID:

ENSECAG00000017031.3

Protein ID:

F6YWM3

Persistent Id:

PTN001372696

Alternate Ids:

F6YWM3(Synonym)	XP_001493186(refSeq)
100061071(GeneID)	ENSECAG00000017031(Ensembl)
149712676(GI)	F6YWM3_HORSE(UniProtKB-ID)
ENSECAP00000014595(Ensembl_PRO)	ENSECAT00000017924(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	TGF-BETA FAMILY (PTHR11848)
PANTHER Subfamily:	GROWTH_DIFFERENTIATION FACTOR 3 (PTHR11848:SF38)
PANTHER GO-slim Molecular Function:	cytokine activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	growth factor

Pathway Categories:

TGF-beta signaling pathway

Transforming growth factor beta

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	protein kinase binding, growth factor activity, cytokine activity
GO BP Complete:	negative regulation of epidermal cell differentiation, signal transduction, endoderm development, mesoderm development, positive regulation of fat cell differentiation, response to dietary excess, formation of anatomical boundary, negative regulation of BMP signaling pathway, eye development, skeletal system development, notochord development, in utero embryonic development, negative regulation of myoblast differentiation, regulation of cell fate commitment, somite rostral/caudal axis specification, primitive streak formation
GO CC Complete:	extracellular space, cytoplasm, extracellular region

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4218\|UniProtKB=Q9NR23	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000004615.4\|UniProtKB=H2Q5C7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000012422.3\|UniProtKB=G3R9N1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000052679.1\|UniProtKB=A0A5F8A9X7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=95686\|UniProtKB=Q07104	Mus musculus	LDO
RAT\|RGD=1564178\|UniProtKB=A2SY89	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000012171.4\|UniProtKB=F1MKJ7	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000023192.5\|UniProtKB=F1MH37	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000000669.4\|UniProtKB=F1SLW3	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000009940.3\|UniProtKB=M3WCE8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845029730.1\|UniProtKB=A0A8I3Q963	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000018006.3\|UniProtKB=F7AL60	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010028173.1\|UniProtKB=Q98950	Gallus gallus	LDO
XENLA\|Gene=dvr1\|UniProtKB=P09534	Xenopus laevis	O
XENLA\|Gene=gdf1.L\|UniProtKB=Q5EAV2	Xenopus laevis	LDO
XENLA\|Gene=Vg1\|UniProtKB=Q5I9F3	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-481419\|UniProtKB=F6UHX6	Xenopus tropicalis	LDO
XENLA\|Gene=gdf3\|UniProtKB=Q9YGV1	Xenopus laevis	O
ORYLA\|Ensembl=ENSORLG00000010335.2\|UniProtKB=H2M3E4	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-980526-389\|UniProtKB=P35621	Danio rerio	LDO
DANRE\|Gene=gdf3\|UniProtKB=A0A8M9PNK2	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000016443.1\|UniProtKB=W5NI50	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118408791\|UniProtKB=A0A9J7HTR0	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC373488\|UniProtKB=P48970	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=GeneID_373196\|UniProtKB=A0A7M7PRU9	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0000490\|UniProtKB=P07713	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007987\|UniProtKB=A0A1S4GXL4	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC008466\|UniProtKB=D2A252	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347232\|UniProtKB=E9FTU5	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW021631\|UniProtKB=B7Q502	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW023553\|UniProtKB=B7QHX4	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG154960\|UniProtKB=T1ELG7	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g194892\|UniProtKB=A7SZ10	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g168498\|UniProtKB=A7SAY4	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG57057\|UniProtKB=B3S0I2	Trichoplax adhaerens	O