PANTHER Gene Information

Gene Symbol(s):

Organism:

Strongylocentrotus purpuratus

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Gene Name:

TGF-beta family profile domain-containing protein

Gene ID:

GeneID_373196

Protein ID:

A0A7M7PRU9

Persistent Id:

PTN000932313

Alternate Ids:

XP_011675185(refSeq)	XM_030998272(Ensembl_TRS)
GeneID_373196(Ensembl)	780100417(GI)
A0A7M7PRU9(Synonym)	XP_030854132(Ensembl_PRO)
A0A7M7PRU9_STRPU(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	TGF-BETA FAMILY (PTHR11848)
PANTHER Subfamily:	PROTEIN DECAPENTAPLEGIC (PTHR11848:SF263)
PANTHER GO-slim Molecular Function:	cytokine activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	growth factor

Pathway Categories:

BMP/activin signaling pathway-drosophila

BMP/activin orthologous ligands

DPP-SCW signaling pathway

decapentaplegic

DPP signaling pathway

decapentaplegic

TGF-beta signaling pathway

Transforming growth factor beta

BMP/activin signaling pathway-drosophila

BMP/activin orthologous ligands

DPP-SCW signaling pathway

decapentaplegic

DPP signaling pathway

decapentaplegic

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	growth factor activity, cytokine activity
GO BP Complete:	-
GO CC Complete:	extracellular space, extracellular region

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4221\|UniProtKB=Q6KF10	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000020439.7\|UniProtKB=K7A0F7	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000023170.2\|UniProtKB=G3RVU6	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000065198.1\|UniProtKB=A0A5F7ZJV3	Macaca mulatta	O
MOUSE\|MGI=MGI=95689\|UniProtKB=P43028	Mus musculus	O
RAT\|RGD=620104\|UniProtKB=Q6HA10	Rattus norvegicus	O
BOVIN\|Gene=GDF6\|UniProtKB=P55106	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000007687.6\|UniProtKB=A0A452DKC3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000034943.2\|UniProtKB=A0A287BJW9	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000006902.3\|UniProtKB=F7BWB4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000042626.2\|UniProtKB=M3XCZ1	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845016606.1\|UniProtKB=A0A8I3NQZ9	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000006980.5\|UniProtKB=A0A5F8HDS8	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000049934.1\|UniProtKB=A0A6I8NKE9	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010011423.1\|UniProtKB=A0A1D5P0D7	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000028474.2\|UniProtKB=R4GCR5	Anolis carolinensis	O
XENLA\|Gene=gdf6.S\|UniProtKB=Q9W753	Xenopus laevis	O
XENLA\|Gene=LOC108719358\|UniProtKB=A0A1L8FZP6	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-6454242\|UniProtKB=A0A6I8S6B0	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000007867.2\|UniProtKB=H2LUS7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-980526-442\|UniProtKB=A8E7N9	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000025052.1\|UniProtKB=A0A3B3I4I5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-980526-373\|UniProtKB=P85857	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000002936.1\|UniProtKB=W5M4Z8	lepisosteus oculatus	O
HUMAN\|HGNC=4220\|UniProtKB=P43026	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000013439.2\|UniProtKB=H2QK94	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000015513.3\|UniProtKB=G3RHL0	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000057979.1\|UniProtKB=A0A5F7ZNE0	Macaca mulatta	O
MOUSE\|MGI=MGI=95688\|UniProtKB=P43027	Mus musculus	O
RAT\|RGD=620102\|UniProtKB=M0RAY4	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000004429.6\|UniProtKB=F1MT44	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000023261.3\|UniProtKB=F1S4W8	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000019421.3\|UniProtKB=F7BKJ7	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000037811.3\|UniProtKB=A0A2I2URW3	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845019680.1\|UniProtKB=A0A8I3PHL7	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000001792.5\|UniProtKB=F6WIE9	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000038918.1\|UniProtKB=A0A6I8NDM7	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010021385.1\|UniProtKB=A0A1D5PGR5	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000005716.3\|UniProtKB=G1KEJ5	Anolis carolinensis	O
XENLA\|Gene=gdf5.S\|UniProtKB=A0A1L8EKU9	Xenopus laevis	O
XENLA\|Gene=gdf5.L\|UniProtKB=Q68KG0	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-481784\|UniProtKB=B5BNX6	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000029983.1\|UniProtKB=A0A3B3I498	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-990415-39\|UniProtKB=F1QK08	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000007687.1\|UniProtKB=W5MLS9	lepisosteus oculatus	O
HUMAN\|HGNC=4222\|UniProtKB=Q7Z4P5	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000011697.6\|UniProtKB=H2QHH9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000000225.3\|UniProtKB=G3QDB1	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000050446.1\|UniProtKB=A0A5F8AMZ6	Macaca mulatta	O
MOUSE\|MGI=MGI=95690\|UniProtKB=P43029	Mus musculus	O
RAT\|RGD=620105\|UniProtKB=F1MAE8	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000038224.3\|UniProtKB=F6QT88	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000028931.3\|UniProtKB=I3LB35	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000021083.3\|UniProtKB=F6W325	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000044521.2\|UniProtKB=A0A337SUJ6	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845020009.1\|UniProtKB=A0A8I3P139	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000041132.1\|UniProtKB=A0A5F8GL90	Monodelphis domestica	O
ANOCA\|Ensembl=ENSACAG00000010676.4\|UniProtKB=G1KKE1	Anolis carolinensis	O
XENLA\|Gene=gdf7.L\|UniProtKB=A0A1L8GBP5	Xenopus laevis	O
XENLA\|Gene=gdf7.S\|UniProtKB=Q9DGN4	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-484925\|UniProtKB=F6Z923	Xenopus tropicalis	O
DANRE\|Gene=gdf7\|UniProtKB=A0A8N7TFB7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000017201.1\|UniProtKB=W5NKV5	lepisosteus oculatus	O
BRAFL\|Gene=LOC118417252\|UniProtKB=A0A9J7LB27	Branchiostoma floridae	O
HUMAN\|HGNC=4214\|UniProtKB=P27539	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000050095.1\|UniProtKB=A0A2I3RPQ5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000025662.2\|UniProtKB=G3SG89	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000023290.4\|UniProtKB=F6ZBU9	Macaca mulatta	O
MOUSE\|MGI=MGI=95683\|UniProtKB=P20863	Mus musculus	O
RAT\|RGD=1304678\|UniProtKB=Q1HI69	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000020923.6\|UniProtKB=E1BEK6	Bos taurus	O
HORSE\|Ensembl=ENSECAG00000026851.3\|UniProtKB=F6SFS6	Equus caballus	O
CANLF\|Ensembl=ENSCAFG00845019828.1\|UniProtKB=A0A8I3P0C2	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000049198.1\|UniProtKB=A0A5F8G6L7	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000004569.3\|UniProtKB=F7E542	Ornithorhynchus anatinus	O
HUMAN\|HGNC=4218\|UniProtKB=Q9NR23	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000004615.4\|UniProtKB=H2Q5C7	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000012422.3\|UniProtKB=G3R9N1	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000052679.1\|UniProtKB=A0A5F8A9X7	Macaca mulatta	O
MOUSE\|MGI=MGI=95686\|UniProtKB=Q07104	Mus musculus	O
RAT\|RGD=1564178\|UniProtKB=A2SY89	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000012171.4\|UniProtKB=F1MKJ7	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000023192.5\|UniProtKB=F1MH37	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000000669.4\|UniProtKB=F1SLW3	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000017031.3\|UniProtKB=F6YWM3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000009940.3\|UniProtKB=M3WCE8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845029730.1\|UniProtKB=A0A8I3Q963	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000018006.3\|UniProtKB=F7AL60	Monodelphis domestica	O
CHICK\|Ensembl=ENSGALG00010028173.1\|UniProtKB=Q98950	Gallus gallus	O
XENLA\|Gene=dvr1\|UniProtKB=P09534	Xenopus laevis	O
XENLA\|Gene=gdf1.L\|UniProtKB=Q5EAV2	Xenopus laevis	O
XENLA\|Gene=Vg1\|UniProtKB=Q5I9F3	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-481419\|UniProtKB=F6UHX6	Xenopus tropicalis	O
XENLA\|Gene=gdf3\|UniProtKB=Q9YGV1	Xenopus laevis	O
ORYLA\|Ensembl=ENSORLG00000010335.2\|UniProtKB=H2M3E4	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-980526-389\|UniProtKB=P35621	Danio rerio	O
DANRE\|Gene=gdf3\|UniProtKB=A0A8M9PNK2	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000016443.1\|UniProtKB=W5NI50	lepisosteus oculatus	O
BRAFL\|Gene=LOC118408791\|UniProtKB=A0A9J7HTR0	Branchiostoma floridae	O
HUMAN\|HGNC=1069\|UniProtKB=P12643	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000013238.4\|UniProtKB=H2QJY1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000022622.2\|UniProtKB=G3RZN8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000064170.1\|UniProtKB=G7N2Y0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=88177\|UniProtKB=P21274	Mus musculus	LDO
RAT\|RGD=2211\|UniProtKB=P49001	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000005111.6\|UniProtKB=A5PJI9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000039442.3\|UniProtKB=A0A286ZZE2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000021201.3\|UniProtKB=A0A9L0SUB3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000037659.3\|UniProtKB=A0A2I2UEZ4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845027004.1\|UniProtKB=A0A8I3QCM6	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000003928.3\|UniProtKB=F7GIY5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000045333.1\|UniProtKB=A0A6I8NNW4	Ornithorhynchus anatinus	LDO
CHICK\|Gene=BMP2\|UniProtKB=Q90751	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010018503.1\|UniProtKB=A0A8V0Z6B6	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000004284.3\|UniProtKB=H9G8Q6	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000044206.1\|UniProtKB=A0A803SPC0	Anolis carolinensis	LDO
XENLA\|Gene=bmp2.S\|UniProtKB=A0A1L8G1N2	Xenopus laevis	O
XENLA\|Gene=bmp2-a\|UniProtKB=P25703	Xenopus laevis	O
XENLA\|Gene=bmp2-b\|UniProtKB=P30884	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-481829\|UniProtKB=Q90YD7	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000028570.1\|UniProtKB=A0A3B3I6L6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-100115-1\|UniProtKB=D2TEB7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014862.1\|UniProtKB=W5NCE2	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000009772.2\|UniProtKB=H2M1H6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-980526-388\|UniProtKB=O13109	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-980526-474\|UniProtKB=O93369	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000016442.1\|UniProtKB=W5NI48	lepisosteus oculatus	LDO
HUMAN\|HGNC=1071\|UniProtKB=P12644	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000051076.1\|UniProtKB=H2Q8B9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000026060.2\|UniProtKB=G3RG26	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000000429.4\|UniProtKB=F7ACJ7	Macaca mulatta	O
MOUSE\|MGI=MGI=88180\|UniProtKB=P21275	Mus musculus	O
RAT\|RGD=2213\|UniProtKB=Q06826	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000003835\|UniProtKB=Q2KJH1	Bos taurus	O
PIG\|Ensembl=ENSSSCG00005024230.1\|UniProtKB=A7LJT9	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000017676.3\|UniProtKB=F6QG82	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000004772.5\|UniProtKB=M3W2U0	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845004370.1\|UniProtKB=A0A8I3MKS3	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000012951.4\|UniProtKB=F7DWN3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000041274.1\|UniProtKB=A0A6I8P6S0	Ornithorhynchus anatinus	O
CHICK\|Gene=BMP4\|UniProtKB=Q90752	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010018174.1\|UniProtKB=A0A8V0Z5C7	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000039001.1\|UniProtKB=A0A803T430	Anolis carolinensis	O
XENLA\|Gene=bmp4.S\|UniProtKB=A0A8J0TPC4	Xenopus laevis	O
XENLA\|Gene=bmp4\|UniProtKB=P30885	Xenopus laevis	O
XENLA\|Gene=bmp4.L\|UniProtKB=A0A8J0TEB6	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-483058\|UniProtKB=Q90YD6	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000013304.2\|UniProtKB=H2MDM6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-980528-2059\|UniProtKB=O57574	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000012132.1\|UniProtKB=W5N2R3	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000019816.1\|UniProtKB=H2XMY6	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118427296\|UniProtKB=A0A9J7N648	Branchiostoma floridae	LDO
DROME\|FlyBase=FBgn0000490\|UniProtKB=P07713	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP007987\|UniProtKB=A0A1S4GXL4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC008466\|UniProtKB=D2A252	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_347232\|UniProtKB=E9FTU5	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW021631\|UniProtKB=B7Q502	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW023553\|UniProtKB=B7QHX4	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG154960\|UniProtKB=T1ELG7	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g194892\|UniProtKB=A7SZ10	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g168498\|UniProtKB=A7SAY4	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG57057\|UniProtKB=B3S0I2	Trichoplax adhaerens	LDO