PANTHER Gene Information   
Gene Symbol(s): DAB2IP
Organism: Equus caballus
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Gene Name: DAB2 interacting protein
Gene ID: ENSECAG00000024868.4
Protein ID: A0A3Q2HBN4
Persistent Id: PTN001303677
Alternate Ids:
ENSECAG00000024868(Ensembl) A0A3Q2HBN4(Synonym)
A0A3Q2HBN4_HORSE(UniProtKB-ID) ENSECAP00000031037(Ensembl_PRO)
ENSECAT00000041005(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: RAS GTPASE-ACTIVATING PROTEINS (PTHR10194)
PANTHER Subfamily: DISABLED HOMOLOG 2-INTERACTING PROTEIN (PTHR10194:SF26)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class: GTPase-activating protein
Pathway Categories: EGF receptor signaling pathway
   GTPase-Activating Protein
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein kinase binding, phosphatidylinositol 3-kinase binding, identical protein binding, phosphatidylinositol 3-kinase regulatory subunit binding, protein homodimerization activity, protein serine/threonine kinase activator activity, signaling adaptor activity, GTPase activator activity, death receptor binding, protein-containing complex binding, phosphatidylinositol-4-phosphate binding, vascular endothelial growth factor receptor 2 binding, SH3 domain binding, phosphatidylinositol-3-phosphate binding, mitogen-activated protein kinase kinase kinase binding, kinase binding, protein phosphatase 2A binding, mitogen-activated protein kinase kinase binding, 14-3-3 protein binding
GO BP Complete: negative regulation of angiogenesis, layer formation in cerebral cortex, negative regulation of cell population proliferation, cell motility involved in cerebral cortex radial glia guided migration, positive regulation of canonical NF-kappaB signal transduction, neuron projection morphogenesis, negative regulation of protein catabolic process, regulation of canonical NF-kappaB signal transduction, negative regulation of canonical NF-kappaB signal transduction, extrinsic apoptotic signaling pathway via death domain receptors, positive regulation of transcription by RNA polymerase II, positive regulation of proteasomal protein catabolic process, negative regulation of transcription by RNA polymerase II, negative regulation of vascular endothelial growth factor signaling pathway, negative regulation of epithelial to mesenchymal transition, negative regulation of DNA-templated transcription, negative regulation of fibroblast proliferation, negative regulation of vascular endothelial growth factor receptor signaling pathway, negative regulation of epithelial cell migration, positive regulation of neuron projection development, cellular response to tumor necrosis factor, regulation of cell cycle, negative regulation of endothelial cell migration, vascular endothelial growth factor receptor-2 signaling pathway, positive regulation of protein-containing complex assembly, intracellular signal transduction, positive regulation of neuron migration, positive regulation of synapse maturation, negative regulation of toll-like receptor 4 signaling pathway, protein catabolic process, regulation of protein-containing complex assembly, positive regulation of protein catabolic process, positive regulation of MAPK cascade, regulation of p38MAPK cascade, positive regulation of dendrite development, negative regulation of canonical Wnt signaling pathway, cellular response to lipopolysaccharide, positive regulation of JNK cascade, negative regulation of ERK1 and ERK2 cascade, positive regulation of apoptotic process, negative regulation of epithelial cell proliferation, cellular response to interleukin-1, cellular response to vascular endothelial growth factor stimulus, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, negative regulation of G0 to G1 transition, tube formation, negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction, positive regulation of apoptotic signaling pathway
GO CC Complete: endocytic vesicle, AIP1-IRE1 complex, cytoplasm, cerebellar mossy fiber, neuronal cell body membrane, neuronal cell body, climbing fiber, plasma membrane, axon, parallel fiber
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: -

Orthologs