PANTHER Gene Information

Gene Symbol(s):

SESN2

Organism:

lepisosteus oculatus

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Gene Name:

Sestrin-2-like

Gene ID:

ENSLOCG00000005106.1

Protein ID:

W5MCN8

Persistent Id:

PTN002647531

Alternate Ids:

ENSLOCT00000006155(Ensembl_TRS)	W5MCN8_LEPOC(UniProtKB-ID)
ENSLOCP00000006147(Ensembl_PRO)	ENSLOCG00000005106(Ensembl)
AHAT01009602(EMBL)	W5MCN8(Synonym)
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PANTHER Classification

PANTHER Family:	P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN (PTHR12474)
PANTHER Subfamily:	SESTRIN-2 (PTHR12474:SF2)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on peroxide as acceptor amino acid binding
PANTHER GO-slim Biological Process:	positive regulation of macroautophagy negative regulation of TORC1 signaling cellular response to oxygen-containing compound cellular response to amino acid starvation cellular response to organonitrogen compound
PANTHER GO-slim Cellular Component:
PANTHER protein class:	peroxidase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	L-leucine binding, oxidoreductase activity, acting on peroxide as acceptor
GO BP Complete:	positive regulation of macroautophagy, regulation of response to reactive oxygen species, negative regulation of TORC1 signaling, cellular response to L-leucine, cellular response to leucine starvation
GO CC Complete:	nucleus, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=20746\|UniProtKB=P58004	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000000429.5\|UniProtKB=K7CUM5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000014485.3\|UniProtKB=G3REY2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000019993.4\|UniProtKB=F7FNU6	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2651874\|UniProtKB=P58043	Mus musculus	LDO
RAT\|RGD=1566319\|UniProtKB=B2GUV6	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000002363\|UniProtKB=Q58CN8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000029438.4\|UniProtKB=A0A4X1TPR3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000001989.4\|UniProtKB=F6Z2X6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000013396.5\|UniProtKB=A0A5F5XNP8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845010570.1\|UniProtKB=A0A8I3NDS6	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000010846.4\|UniProtKB=F7ARK8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000000634.4\|UniProtKB=F7END0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010016875.1\|UniProtKB=A0A8V0YY05	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010993.4\|UniProtKB=H9GH47	Anolis carolinensis	LDO
XENLA\|Gene=sesn2.S\|UniProtKB=A0A8J1ME70	Xenopus laevis	O
XENLA\|Gene=sesn2.L\|UniProtKB=Q6NU55	Xenopus laevis	LDO
XENTR\|Gene=sesn2\|UniProtKB=A0A8J1J4K5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000011116.2\|UniProtKB=H2M654	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-070108-1\|UniProtKB=A0F081	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000007668.3\|UniProtKB=F6T7E5	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118423082\|UniProtKB=A0A9J7LQS3	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC584902\|UniProtKB=A0A7M7PFI8	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00022279\|UniProtKB=Q9N4D6	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG03915\|UniProtKB=A8WVR0	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00117377\|UniProtKB=A0A2A6BL70	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0034897\|UniProtKB=Q9W1K5	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP007169\|UniProtKB=Q7PTB1	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC003553\|UniProtKB=D6WHQ5	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_200622\|UniProtKB=E9H5P4	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW002773\|UniProtKB=B7P7V9	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG117076\|UniProtKB=T1EGK0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG185938\|UniProtKB=T1FNG7	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g188161\|UniProtKB=A7SCG7	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG25289\|UniProtKB=B3RYA9	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_1017\|UniProtKB=A9UW02	Monosiga brevicollis	LDO
DICDI\|dictyBase=DDB_G0279427\|UniProtKB=Q54WU6	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_98918\|UniProtKB=F0ZUS8	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_18_0650\|UniProtKB=Q4QDX6	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.05.0190\|UniProtKB=Q388Q1	Trypanosoma brucei	LDO
PARTE\|EnsemblGenome=GSPATT00006213001\|UniProtKB=A0C4J8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00023191001\|UniProtKB=A0E401	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00009541001\|UniProtKB=A0CR11	Paramecium tetraurelia	O
PHYRM\|Gene=H3GGE2_PHYRM\|UniProtKB=H3GGE2	Phytophthora ramorum	LDO