PANTHER Gene Information

Gene Symbol(s):

Organism:

lepisosteus oculatus

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Gene Name:

receptor protein-tyrosine kinase

Gene ID:

ENSLOCG00000014152.1

Protein ID:

W5N9Y7

Persistent Id:

PTN002814377

Alternate Ids:

ENSLOCT00000017477(Ensembl_TRS)	W5N9Y7(Synonym)
W5N9Y7_LEPOC(UniProtKB-ID)	ENSLOCP00000017446(Ensembl_PRO)
ENSLOCG00000014152(Ensembl)	AHAT01002265(EMBL)
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PANTHER Classification

PANTHER Family:	TYROSINE-PROTEIN KINASE RECEPTOR (PTHR24416)
PANTHER Subfamily:	PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA (PTHR24416:SF52)
PANTHER GO-slim Molecular Function:	growth factor binding transmembrane receptor protein tyrosine kinase activity
PANTHER GO-slim Biological Process:	transmembrane receptor protein tyrosine kinase signaling pathway chordate embryonic development embryonic organ development positive regulation of kinase activity embryonic morphogenesis animal organ morphogenesis skeletal system development
PANTHER GO-slim Cellular Component:	receptor complex plasma membrane
PANTHER protein class:	transmembrane signal receptor

Pathway Categories:

PDGF signaling pathway

Platelet-Derived Growth Factor A

Angiogenesis

Platelet-Derived Growth Factor Receptor

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	placental growth factor receptor activity, stem cell factor receptor activity, brain-derived neurotrophic factor receptor activity, macrophage colony-stimulating factor receptor activity, protein tyrosine kinase collagen receptor activity, insulin-like growth factor receptor activity, vascular endothelial growth factor receptor activity, boss receptor activity, GPI-linked ephrin receptor activity, epidermal growth factor receptor activity, platelet-derived growth factor binding, transmembrane-ephrin receptor activity, hepatocyte growth factor receptor activity, platelet-derived growth factor beta-receptor activity, fibroblast growth factor receptor activity, platelet-derived growth factor alpha-receptor activity, ATP binding, protein tyrosine kinase activity, insulin receptor activity, transmembrane receptor protein tyrosine kinase activity, metal ion binding
GO BP Complete:	vascular endothelial growth factor receptor-1 signaling pathway, multicellular organism development, insulin receptor signaling pathway, epidermal growth factor receptor signaling pathway, platelet-derived growth factor receptor-alpha signaling pathway, macrophage colony-stimulating factor signaling pathway, platelet-derived growth factor receptor-beta signaling pathway, vascular endothelial growth factor signaling pathway, insulin-like growth factor receptor signaling pathway, cell surface receptor protein tyrosine kinase signaling pathway, fibroblast growth factor receptor signaling pathway, embryonic cranial skeleton morphogenesis, collagen-activated tyrosine kinase receptor signaling pathway, hepatocyte growth factor receptor signaling pathway, brain-derived neurotrophic factor receptor signaling pathway, ephrin receptor signaling pathway, Kit signaling pathway
GO CC Complete:	receptor complex, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8803\|UniProtKB=P16234	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000016066.4\|UniProtKB=H2QPH4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010615.3\|UniProtKB=G3R4Z2	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=97530\|UniProtKB=P26618	Mus musculus	LDO
RAT\|RGD=3284\|UniProtKB=P20786	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000007173.6\|UniProtKB=F1MX49	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000008841.6\|UniProtKB=A0A287AYB4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000018176.4\|UniProtKB=F7A2X2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000009141.6\|UniProtKB=M3WAV8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845011775.1\|UniProtKB=A0A8I3NAN8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000020670.3\|UniProtKB=F7E5I9	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000003786.3\|UniProtKB=F6V0P7	Ornithorhynchus anatinus	LDO
CHICK\|Gene=PDGFRA\|UniProtKB=Q9PUF6	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010013621.1\|UniProtKB=A0A8V0YKS4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010297.4\|UniProtKB=G1KK54	Anolis carolinensis	LDO
XENLA\|Gene=pdgfra.L\|UniProtKB=A0A1L8HTV1	Xenopus laevis	O
XENLA\|Gene=pdgfra\|UniProtKB=P26619	Xenopus laevis	LDO
XENLA\|Gene=pdgfra.S\|UniProtKB=A0A1L8HLA2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6072920\|UniProtKB=A4IHL2	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000019815.2\|UniProtKB=H2MZV1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-990415-208\|UniProtKB=Q9DE49	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000003493.3\|UniProtKB=F6TLX0	Ciona intestinalis	O
BRAFL\|Gene=LOC118418363\|UniProtKB=A0A9J7MV71	Branchiostoma floridae	O
BRAFL\|Gene=LOC118403946\|UniProtKB=A0A9J7HIK2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118419709\|UniProtKB=A0A9J7LFS0	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC105444281\|UniProtKB=A0A7M7NBJ5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105438002\|UniProtKB=A0A7M7NGH8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC579430\|UniProtKB=A0A7M7NBH9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105437797\|UniProtKB=A0A7M7P5W9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918442\|UniProtKB=A0A7M7NFV5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC575248\|UniProtKB=A0A7M7NGI9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105443986\|UniProtKB=A0A7M7NDD9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC593142\|UniProtKB=A0A7M7PJZ3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105445932\|UniProtKB=A0A7M7NC15	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105444011\|UniProtKB=A0A7M7NDZ4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105443826\|UniProtKB=A0A7M7NBR9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105439256\|UniProtKB=A0A7M7NFB8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100892684\|UniProtKB=A0A7M7NF85	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115921149\|UniProtKB=A0A7M7NC60	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105444275\|UniProtKB=A0A7M7ND25	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC590825\|UniProtKB=A0A7M7NBI9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100888196\|UniProtKB=A0A7M7LL81	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100888329\|UniProtKB=A0A7M7P467	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC579837\|UniProtKB=A0A7M7RCU0	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00017310\|UniProtKB=A0A2C9C3B4	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG19102\|UniProtKB=A8XUS9	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00103469\|UniProtKB=A0A2A6CRG6	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00008599\|UniProtKB=Q19238	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG05239\|UniProtKB=A8WZG4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00107078\|UniProtKB=A0A2A6CZ19	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00002195\|UniProtKB=F3NWW5	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG22767\|UniProtKB=A8Y2V0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00276578\|UniProtKB=A0A2A6B4J7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00015087\|UniProtKB=Q10915	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG11187\|UniProtKB=A8XCN3	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00304683\|UniProtKB=A0A8R1Z946	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00011169\|UniProtKB=Q21868	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00002199\|UniProtKB=P34891	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00011339\|UniProtKB=O18008	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00002200\|UniProtKB=P34892	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG04906\|UniProtKB=A8WYS1	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG13386\|UniProtKB=A8XHW0	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG13385\|UniProtKB=A8XHW1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00020678\|UniProtKB=A0A1I6CMA1	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG01733\|UniProtKB=A8WQZ3	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00021745\|UniProtKB=Q9N4T2	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00003862\|UniProtKB=Q17833	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00002211\|UniProtKB=O17955	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00003863\|UniProtKB=Q23677	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00011168\|UniProtKB=Q21867	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00012270\|UniProtKB=Q95ZK1	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00027499\|UniProtKB=A8WYS2	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG04913\|UniProtKB=A8WYS8	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00027448\|UniProtKB=A8WYM1	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00027500\|UniProtKB=A8WYS3	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00006897\|UniProtKB=Q21041	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00006894\|UniProtKB=G5ED65	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00006896\|UniProtKB=Q21038	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG17535\|UniProtKB=A8XR68	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG17536\|UniProtKB=A8XR69	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG17534\|UniProtKB=A8XR67	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00278186\|UniProtKB=A0A2A6B1V3	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00278185\|UniProtKB=A0A2A6B2E3	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0032006\|UniProtKB=E1JHB7	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008813\|UniProtKB=A0A1S4GZA9	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC007584\|UniProtKB=A0A139WIY2	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_58385\|UniProtKB=E9H5T6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_305264\|UniProtKB=E9GQ40	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_48616\|UniProtKB=E9GD08	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_4284\|UniProtKB=E9GD15	Daphnia pulex	O
DAPPU\|Gene_ORFName=DAPPUDRAFT_44144\|UniProtKB=E9FZB6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_43719\|UniProtKB=E9FZF2	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_308023\|UniProtKB=E9H5G0	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_114299\|UniProtKB=E9HHQ5	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_130278\|UniProtKB=E9HM17	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_110024\|UniProtKB=E9H4Z3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_325477\|UniProtKB=E9H4U6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_331276\|UniProtKB=E9HLZ6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_110251\|UniProtKB=E9H5G3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_61463\|UniProtKB=E9HD20	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_119760\|UniProtKB=E9HZE7	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_302458\|UniProtKB=E9HNF0	Daphnia pulex	O
DAPPU\|Gene_ORFName=DAPPUDRAFT_48631\|UniProtKB=E9GCS3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_108386\|UniProtKB=E9H018	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_53509\|UniProtKB=E9GQD0	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_308030\|UniProtKB=E9H5J0	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_253800\|UniProtKB=E9H5G1	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_58353\|UniProtKB=E9H5T9	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_64428\|UniProtKB=E9HNF3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_302459\|UniProtKB=E9HNF4	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_130102\|UniProtKB=E9HGU7	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW005359\|UniProtKB=B7PKS1	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG133386\|UniProtKB=T1EI07	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG170959\|UniProtKB=T1F3M5	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG75629\|UniProtKB=T1G278	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG141355\|UniProtKB=T1EJ33	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG89500\|UniProtKB=T1G7D9	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g94990\|UniProtKB=A7RVU0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g115371\|UniProtKB=A7SEI8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g94997\|UniProtKB=A7RVT8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g87486\|UniProtKB=A7RN88	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g87445\|UniProtKB=A7RN91	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG50752\|UniProtKB=B3S5N3	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG25090\|UniProtKB=B3RWV1	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_30176\|UniProtKB=A9VD80	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_2692\|UniProtKB=A9UPY9	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_27311\|UniProtKB=A9V4X6	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_34526\|UniProtKB=A9VCA3	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_33842\|UniProtKB=A9V7V7	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_33860\|UniProtKB=A9V7Z4	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_44299\|UniProtKB=A9V2D0	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_44298\|UniProtKB=A9UWK2	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_27155\|UniProtKB=A9V4G9	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_16001\|UniProtKB=A9UW70	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_27552\|UniProtKB=A9V5L8	Monosiga brevicollis	O